Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,022 recruiting studies in this area right now.
By phase
- Not applicable7,998
- Phase 2485
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure565
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)144
- Acute Ischemic Stroke141
- Pulmonary Hypertension102
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama198
- Massachusetts181
- Arizona176
- New York165
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,019 total
- NCT06809686Recruiting
ECG and patient experience study for heart failure
This study collects detailed ECG data and feedback from people with heart failure to better understand the condition and improve care. It involves noninvasive monitoring and a discussion of your symptoms and daily life.
London, LondonAges 45–80 - NCT06810661Recruiting
Mobilizing patients with heart disease to reduce frailty
This study tests whether a gentle movement program helps people with heart disease stay stronger and more independent during their hospital stay. If you are staying in a specific unit at the Vitalité Health Network and have a heart condition, you may be able to join.
Moncton, New BrunswickAges 18 years+ - NCT06810726RecruitingPhase 2
Platelet-rich fibrin gel for diabetic foot ulcers
This trial tests a special gel made from your own blood (platelet-rich fibrin, or PRF) to help heal diabetic foot ulcers that are not getting better with standard care. It may be an option if you have a mild-to-moderate ulcer on the bottom of your foot with good blood flow and no infection.
Corpus Christi, TexasAges 18–80 - NCT06810817Recruiting
Brain stimulation and talk therapy for post-stroke fatigue
This trial tests whether a combination of gentle brain stimulation (tDCS) and a talking therapy program can help reduce fatigue after a stroke. It aims to find a safe, non-drug way to improve energy and quality of life for stroke survivors.
Hong KongAges 50–80 - NCT06811519Recruiting
AI predicts heart function from ultrasound and body scans
This study uses artificial intelligence to predict how well your heart is pumping by looking at your heart ultrasound results and body composition (like body fat and muscle). The goal is to see if adding body composition data makes the AI predictions more accurate.
Yongin, Gyeonggi-doAges 20 years+ - NCT06811896Recruiting
Stress management for heart health in women with HIV
This study tests a stress management program designed to help reduce the risk of heart disease in women with HIV. Researchers want to see if learning stress reduction skills can improve heart health.
Birmingham, AlabamaAges 18 years+ - NCT06812455RecruitingPhase 4
Rivaroxaban for blood clot after heart catheterization
This trial tests if a blood thinner called Rivaroxaban can treat a blood clot that forms in the wrist artery after a heart catheterization. If you have this clot, taking Rivaroxaban may help reopen the artery and improve blood flow.
ThessalonikiAges 18 years+ - NCT06812520Recruiting
Education to Help With Compression for Vein Ulcers
This study tests whether an educational program helps people with a grade 2 vein ulcer stick with compression treatment (bandages or stockings). It focuses on Spanish-speaking adults who have already started compression therapy.
Hualpén, BiobioAges 20 years+ - NCT06813443Recruiting
Studying cardiomyopathy to find who needs a heart transplant
This study is looking at people with cardiomyopathy to understand which patients are most in need of a heart transplant. By joining, you will help doctors learn more about critical cases and improve care for heart muscle disease.
Bologna, Emilia-Romagna/BolognaAges 12 years+ - NCT06813534Recruiting
IVUS-guided stent placement for kidney disease patients
This trial tests whether using a special ultrasound camera inside the artery (IVUS) to guide stent placement can improve outcomes for people with serious kidney disease. The goal is to use less contrast dye and protect the kidneys better.
Créteil, CreteilAges 18 years+ - NCT06813651RecruitingPhase 2
TBO-309 for stroke with tandem blockage
This trial tests whether adding TBO-309 to standard treatment helps people having a stroke caused by two blockages (one in the neck, one in the brain). It may limit brain damage and improve recovery.
Newcastle, New South WalesAges 18 years+ - NCT06813911RecruitingPhase 3
Testing pelacarsen for high Lp(a) in heart disease patients
This trial tests a new medicine called pelacarsen for people with very high Lp(a) (a type of cholesterol) and existing heart or blood vessel disease. It aims to see if adding pelacarsen to your current cholesterol treatment can lower your Lp(a) levels further.
Birmingham, AlabamaAges 18–80 - NCT06814509Recruiting
HOPE program for pregnant women
This study tests a program called HOPE that helps pregnant women get the support they need for a healthy pregnancy. It is designed to make prenatal care more fair and accessible.
Corning, ArkansasAges 16–44 - NCT06814574Recruiting
Pacemaker after tricuspid valve replacement
This study looks at whether people who need a new tricuspid heart valve also need a pacemaker soon after. Researchers want to learn more about heart rhythm changes after valve replacement.
München, BavariaAges Any age - NCT06814587Recruiting
New imaging for heart muscle damage after a heart attack
This study uses special imaging scans (MRI and PET) to look at the health of the heart muscle in people with advanced heart failure caused by blocked arteries. The goal is to better predict recovery after bypass surgery.
Dallas, TexasAges 20–80 - NCT06815159Recruiting
Tissue markers for early AV fistula narrowing
This study looks at tissue samples from people getting or fixing an AV fistula for dialysis. The goal is to find markers that might predict early narrowing (stenosis) of the fistula, so doctors can prevent problems in the future.
BolognaAges 18 years+ - NCT06816485Recruiting
New balloon safety in TAVI for severe aortic stenosis
This trial studies a new balloon used during a TAVI procedure to replace your aortic valve without open-heart surgery. It aims to see if the balloon is safe and works well for people with severe aortic stenosis.
BarcelonaAges 18 years+ - NCT06816641Recruiting
Surgery for spontaneous brain bleed: outcomes and factors
This trial studies how well surgery works for people who have a spontaneous brain bleed (not from injury) and looks at factors that might affect recovery. It may help doctors better predict who benefits from surgery.
SohagAges 20–70 - NCT06817148Recruiting
TAVR vs surgery for bicuspid aortic valve disease
This study compares two treatments for severe aortic stenosis in people with a bicuspid aortic valve: transcatheter aortic valve replacement (TAVR, a less invasive procedure) and surgical aortic valve replacement (SAVR, open-heart surgery). The goal is to see which approach works better for this specific condition.
Los Angeles, CaliforniaAges 50 years+ - NCT06817252Recruiting
Mediterranean diet with potatoes for pre-diabetes
This study tests whether adding potatoes to a Mediterranean diet can improve heart health and blood sugar control in adults with pre-diabetes. You'll follow a specific meal plan and be monitored over time.
Las Vegas, NevadaAges 45–80 - NCT06817434Recruiting
Statin treatment for Moyamoya disease study
This study tests if statins (cholesterol-lowering drugs) can help people with Moyamoya disease. The trial will follow patients who receive either surgery or standard care to see if adding a statin improves outcomes.
Beijing, ChinaAges 18–60 - NCT06817642Recruiting
Language recovery in stroke patients in intensive care
This study tests a new language assessment tool to predict how well stroke patients may recover their ability to speak and understand language. It may help identify who could benefit from early speech therapy.
CréteilAges 18–85 - NCT06818084RecruitingPhase 4
TAVR for severe aortic regurgitation using VitaFlow Liberty
This trial tests the VitaFlow Liberty device, a catheter-based treatment for people with severe aortic regurgitation (a leaky heart valve). If you have symptoms or your heart is starting to weaken, this procedure might help avoid open-heart surgery.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06818149Recruiting
Studying heart inflammation from immunotherapy in lung cancer
This study looks for specific markers in the blood that can help doctors better understand and treat heart inflammation (myocarditis) caused by immunotherapy in people with lung cancer. If you join, you will help find ways to improve care for other patients.
ShanghaiAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,022 recruiting cardiology studies from the U.S. registry right now, out of 15,398 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.