Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06837103Recruiting
Continuous glucose monitor and coaching for type 2 diabetes
This real-world study tests whether using a continuous glucose monitor (isCGM) with or without pharmacist coaching helps people with type 2 diabetes who are not on insulin improve their blood sugar control. It compares these approaches to standard blood sugar checking and looks for better HbA1c results after three months.
Toronto, OntarioAges 18 years+ - NCT06951386Recruiting
Can a daily drink improve heart and metabolic health?
This trial tests whether taking a daily drink containing short-chain fatty acids can improve risk factors for metabolic syndrome, like belly fat, high blood sugar, or high blood pressure. It might help if you are at risk but not yet taking medications for these conditions.
Leuven, Vlaams-BrabantAges 18–65 - NCT07151443Recruiting
Comparing two ways to numb the arm for hand surgery in people with obesity
This study compares two ways of numbing the arm for forearm or hand surgery in people who are obese. One method places the numbing medicine near the collarbone from the front, and the other from behind the collarbone. The goal is to see which way works better.
Yenimahalle, AnkaraAges 18–80 - NCT07145229RecruitingPhase 2
Testing a new drug for acute gout flares
This trial tests a new medication, ABP-745, for people having an acute gout flare. It aims to see if the drug is safe and helps reduce pain and inflammation.
Peoria, ArizonaAges 18–70 - NCT07151001Recruiting
AI test for early diabetic eye disease (retinopathy)
This trial uses an AI system to test if it can find early signs of diabetic eye disease (diabetic retinopathy) in people with diabetes. If you have diabetes but no known eye problems, the AI might help catch issues early.
Richmond Hill, New YorkAges 22 years+ - NCT07145255RecruitingPhase 1/Phase 2
Study of MBRC-201 for advanced solid tumors
This trial tests a new drug, MBRC-201, for people with advanced solid tumors that have not responded to standard treatments. The goal is to find the best dose and see if it helps shrink tumors or slow their growth.
San Francisco, CaliforniaAges 18 years+ - NCT07146347RecruitingPhase 1
Comparing a new long-acting insulin for type 2 diabetes
This study tests a new once-daily insulin (GZR4) against an approved insulin (degludec) in people with type 2 diabetes to see how well it controls blood sugar. You may qualify if you are already using a stable dose of background insulin.
NeussAges 18–70 - NCT07154238Enrolling by invitation
Semaglutide for weight management: a real-world study
This study looks at the experiences of people using injectable semaglutide for weight loss, as well as the doctors who prescribe it. It aims to understand how the treatment works in everyday life.
Bad OeynhausenAges 18 years+ - NCT07148128RecruitingPhase 1/Phase 2
Testing the safety of WEF-001 for KRAS-mutant cancers
This trial studies a new drug called WEF-001 for people with advanced cancers that have a KRAS mutation. It aims to see if the drug is safe and shrinks tumors when used alone.
Dallas, TexasAges 18 years+ - NCT07149064Recruiting
Effect of Nextida GC-B on Blood Sugar in Prediabetes
This study tests whether a nutritional supplement called Nextida GC-B helps control blood sugar in people who either have normal blood sugar or prediabetes. It looks at how the supplement affects blood sugar levels over time using a continuous glucose monitor.
London, OntarioAges 18 years+ - NCT07145151RecruitingPhase 2
Studying UBT251 for MASH liver disease
This trial tests a new medication called UBT251 for people with MASH, a type of liver disease linked to weight and metabolism. It aims to see if the medicine can reduce liver damage and scarring.
Beijing, Beijing MunicipalityAges 18–75 - NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT07150962RecruitingPhase 1
Testing a new version of an obesity treatment pill
This trial compares two versions of the study drug HRS9531 in people with overweight or obesity to see which one works better in the body. It may help find a more effective treatment for weight management.
Hefei, AnhuiAges 18–55 - NCT07153172RecruitingPhase 1
Safety follow-up for people who got INV-347
This study checks on the long-term safety of people who already received the study drug INV-347 in a previous trial. You'll have your blood tested to see how much of the drug is still in your system.
QuébecAges 18 years+ - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04255264Recruiting
Study of fat inflammation in people after gastric bypass
This study looks at “fat inflammation” and diabetes in people who had gastric bypass surgery. It may help doctors understand why some people develop diabetes and how weight-related body changes affect health.
Gothenburg, Västra Götaland CountyAges 18–60 - NCT07154381Recruiting
Hybrid PET/MRI for heart amyloidosis imaging
This study uses a hybrid PET/MRI scanner to take detailed images of the heart in people with amyloidosis. The goal is to see how well this scan shows the buildup of amyloid protein, which could help doctors better diagnose and manage the condition.
Essen, North Rhine-WestphaliaAges 40 years+ - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months - NCT07145567Recruiting
Study of small blood vessel disease in type 1 diabetes
This study looks at small blood vessel disease (microangiopathy) in people with type 1 diabetes. It will use special devices to examine your skin and blood vessels to understand how diabetes affects them.
Danderyd, Stockholm CountyAges 18–60 - NCT07148921Recruiting
Pain perception during gender affirming hormone therapy
This study looks at how starting gender affirming hormone therapy may change your experience of pain. If you are an adult assigned female at birth planning to start testosterone, or an adult assigned male at birth planning to start estradiol, and you have not taken any sex hormones in the past six months, this trial wants to measure your pain perception over time.
Vienna, State of ViennaAges 18 years+ - NCT07154251Recruiting
Community health workers as diabetes tech coaches for kids
This trial tests whether a community health worker can help Black children with type 1 diabetes use their automated insulin delivery system (a combination of a continuous glucose monitor and an insulin pump) more effectively. Children who are already using or have used this system in the past 3 months may qualify.
Cleveland, OhioAges 5–17 - NCT07149142Recruiting
AI eye screening for children with type 1 diabetes
This study tests if an artificial intelligence (AI) system can effectively screen for eye problems related to diabetes (retinopathy) in children. The goal is to find a faster, easier way to protect your child's vision.
Prague, Prague 5Ages 11–19 - NCT07151105Recruiting
Vitamin C for gut health in adults with obesity
This trial tests whether taking vitamin C supplements helps improve gut barrier function in adults with obesity. You'll follow a low-fruit-and-vegetable diet for two, two-week periods.
Columbus, OhioAges 18–50
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.