Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07152366RecruitingPhase 4
Hormone and tetuzumab for active thyroid eye disease
This trial tests a new sequence of hormone therapy followed by a targeted drug (tetuzumab) for people with moderate to severe thyroid eye disease that is still active after steroid treatment didn't help enough.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07147790Enrolling by invitation
Silver spray and wound vacuum for diabetic foot wounds
This trial compares a special wound vacuum that adds silver nanoparticle spray to a standard wound vacuum. It's for people with diabetic foot wounds after a procedure to restore blood flow to their leg.
Kafr ash Shaykh, Kafrelshaykh GovernorateAges 40–80 - NCT07150000Recruiting
Rheumatic disease research study for patients and healthy volunteers
This study is for people with certain rheumatic conditions (like arthritis, lupus, or vasculitis) and for healthy volunteers. It aims to learn more about these diseases and improve how they are treated.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07154251Recruiting
Community health workers as diabetes tech coaches for kids
This trial tests whether a community health worker can help Black children with type 1 diabetes use their automated insulin delivery system (a combination of a continuous glucose monitor and an insulin pump) more effectively. Children who are already using or have used this system in the past 3 months may qualify.
Cleveland, OhioAges 5–17 - NCT07154719RecruitingPhase 4
Testing a weight loss drug's effect on muscle and bone
This study tests a medication called tirzepatide (a type of GLP-1 drug) to see how it affects muscle and bone health during weight loss. It is for people with obesity who are not menopausal and do not have diabetes or bone disease.
Baton Rouge, LouisianaAges 18–50 - NCT07149610Recruiting
Connected care for type 2 diabetes self-management
This study tests a connected care program to help people with type 2 diabetes manage their condition better using a smartphone. It may help you if your blood sugar is not well controlled and you live in the Marche region of Italy.
Ancona, AnconaAges 18 years+ - NCT07154134Recruiting
Blood markers in preterm babies with breathing problems
This study looks at two substances in the blood (endocan and copeptin) to see if they can help doctors understand breathing problems in premature babies. It may lead to better ways to care for these infants.
Tanta, El-GharbiaAges 6 months–8 months - NCT07154394Recruiting
Heart amyloid and function in Alzheimer's disease
This study examines whether amyloid plaques in the heart affect heart function in people with Alzheimer's disease. It uses brain amyloid PET and MRI scans to explore a potential link.
Essen, North Rhine-WestphaliaAges 18 years+ - NCT07151222Recruiting
Red blood cells and heart disease in type 2 diabetes
This study looks at the role of red blood cells in heart disease risk for people with type 2 diabetes. It may help us understand how to better prevent heart problems.
Stockholm, SwsdenAges 25–80 - NCT07152392RecruitingPhase 4
Testing IBI311 for inactive thyroid eye disease symptoms
This trial tests a medication called IBI311 for people with inactive thyroid eye disease that still causes bothersome symptoms like double vision or trouble closing the eyes. The goal is to see if it helps improve these problems safely.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT04776824Recruiting
Swiss registry for people with amyloidosis and possible heart involvement
This trial is a registry that collects health information from people with amyloidosis, including cases where the heart may be involved. Sharing your medical details can help researchers learn how this condition affects patients and may guide future care.
BaselAges 18 years+ - NCT06582875RecruitingPhase 2
GLP-1 drug for polycystic kidney disease and weight
This study tests a GLP-1 receptor agonist (a type of medicine that helps with weight and metabolism) in people with polycystic kidney disease who are overweight. It aims to see if this drug can help slow kidney disease progression.
Aurora, ColoradoAges 18–65 - NCT06958302Recruiting
Diabetes Nerve Damage and Muscle Mass in Type 2 Diabetes
This study examines how nerve damage from diabetes (diabetic neuropathy) relates to muscle loss in people with type 2 diabetes. It aims to help understand and possibly prevent muscle weakness.
Cairo, AbbassiaAges 45 years+ - NCT06318585Recruiting
Building a database for motor neuron disease research
This study collects information from people with ALS or other motor neuron diseases to better understand how these conditions vary. By joining a database, you help researchers find patterns that could improve care.
Milan, MIAges 18 years+ - NCT06318598Recruiting
ALS and motor neuron disease biomarker study
This study looks for biological markers in people with ALS or other motor neuron diseases to better understand the different types of the disease. It may help find new ways to treat or manage these conditions.
Milan, MIAges 18 years+ - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
San Francisco, CaliforniaAges 8–45 - NCT07142707RecruitingPhase 1
Testing a new obesity drug for safety and effects
This study tests an investigational medication called MBX 4291 for adults with obesity. It aims to see if the drug is safe and how it works in the body, which could lead to a new weight-loss treatment option.
Doral, FloridaAges 18–65 - NCT07142291RecruitingPhase 2
Cromolyn inhaler for early ALS
This trial tests if an inhaled drug called cromolyn can help people with early-stage ALS. It is for people who can still breathe well and are not yet using a ventilator.
Scottsdale, ArizonaAges 18–75 - NCT07135570Recruiting
My Eyes, My Light: Amar Chokh, Amar Alo
This trial is studying people living in Char Fasson, Bangladesh, to see who might have undiagnosed eye problems. It's a local screening program to catch eye issues early.
Char Fasson, BholaAges 35 years+ - NCT07140783RecruitingPhase 3
Eye drops to improve night vision after laser eye surgery
This study tests an eye drop that may help people who had laser eye surgery before 2010 and now have trouble seeing in dim light, such as glare, halos, or starbursts at night. The drops are given at home and may improve vision in low light.
Chandler, ArizonaAges 18 years+ - NCT07144098RecruitingPhase 1
GZR18 injection study for people with and without liver problems
This study tests a new drug called GZR18 to see how it works in people with different levels of liver function. It aims to help find the right dose and check safety.
BeijingAges 18–75 - NCT07140809RecruitingPhase 1/Phase 2
Study of JMT202 for people with high triglycerides
This trial tests a new injectable drug, JMT202, for people with high triglycerides (a type of fat in the blood). The goal is to see if it safely lowers triglycerides and may reduce heart risk.
Beijing, Beijing MunicipalityAges 18–75 - NCT07141030RecruitingPhase 1
Study of GZR18 in people with and without kidney problems
This trial tests how a new drug called GZR18 (given as an injection) affects the body in people with different levels of kidney function. It aims to find the right dose and check for side effects, which could help guide treatment for people with kidney issues.
BeijingAges 18–75 - NCT06960746Recruiting
Lifestyle change for sleep apnea, metabolic syndrome, and impotence
This trial tests whether changing your lifestyle can help men with sleep apnea, metabolic syndrome, and erectile dysfunction. It studies how improving diet and exercise might improve these conditions together.
Giza, DokkiAges 40–50
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.