Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT07109128Enrolling by invitation
T1D talks: a support study for type 1 diabetes
This study tests a virtual program where people with type 1 diabetes talk with peers and a coach. It aims to help you manage daily life and feel supported.
Orlando, FloridaAges 12–14 - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT07107087Recruiting
Combined therapy for weight loss and muscle weakness in kidney dialysis
This study tests a program combining exercise, nutritional support, and omega-3 supplements to help kidney dialysis patients who have lost weight and muscle strength. It aims to improve appetite, energy levels, and physical function.
Antrim, County AntrimAges 18 years+ - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07111351Recruiting
Studying hormones and genes in adrenal gland conditions
This study looks at the genes and molecules in people with primary aldosteronism (a condition where the adrenal glands make too much of the hormone aldosterone), primary hypertension (high blood pressure), and healthy volunteers. The goal is to better understand these conditions and find better ways to diagnose and treat them.
Beijing, Beijing MunicipalityAges 18–80 - NCT07115082RecruitingPhase 1/Phase 2
Stem cells from amniotic fluid for early menopause
This study tests whether stem cells from the fluid around a baby (amniotic membrane) can help women with premature ovarian insufficiency improve their chances of getting pregnant. It is designed for women under 40 who have not had a period for months and have high FSH levels.
ShanghaiAges 20–40 - NCT05917587RecruitingEarly Phase 1
Metformin for blood-vessel function after pregnancy diabetes
This early study tests whether metformin can improve how small blood vessels work after gestational diabetes (pregnancy diabetes). It may help some people who feel long-term effects after delivery by improving blood-vessel-related function.
Iowa City, IowaAges 18–45 - NCT06332274RecruitingPhase 3
Tislelizumab for cancer patients with minimal residual disease
This trial is for people who have completed standard cancer treatments (like surgery, chemo or radiation) and have no visible cancer on scans, but may still have very small amounts of cancer DNA in their blood. The study tests whether the drug tislelizumab can help prevent the cancer from coming back.
Villejuif, Val De MarneAges 18 years+ - NCT06341699Recruiting
Hormones in severe obesity
This study looks at hormone levels in people with severe obesity to understand how they differ from others. It may help explain how obesity affects the body.
Oggebbio, VerbaniaAges 18–80 - NCT06969209Recruiting
Brain aging in adults with PKU
This study looks at how the brain ages in adults with PKU. It uses an MRI scan to compare brain changes between people with PKU and healthy volunteers.
BernAges 18 years+ - NCT06937060RecruitingPhase 3
Semaglutide for psoriasis and obesity
This trial tests if semaglutide, a medicine used for diabetes and weight loss, can help people with both psoriasis and obesity. You may qualify if you have moderate to severe psoriasis, a high body weight, and are of Chinese descent.
Hong KongAges 18–75 - NCT06968234Recruiting
Liver disease breath test study
This study uses a special breath test to learn about chronic liver disease. If you have liver disease or cirrhosis, you may be able to help by providing a breath sample.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06969391Recruiting
Diet and type 2 diabetes in migrant patients
This study looks at how diet affects type 2 diabetes in people who moved to France. It aims to understand your eating habits and help manage your blood sugar better.
Saint-DenisAges 18 years+ - NCT06966635RecruitingPhase 4
Potassium citrate for gout treatment
This study tests whether a potassium citrate tablet can help people with gout lower uric acid and prevent flares. It is for adults on stable gout medication who are not having a current flare.
ShanghaiAges 18–70 - NCT07098598RecruitingPhase 2/Phase 3
Using FAPI-PET to diagnose pancreatic cancer
This trial uses a special imaging scan called FAPI-PET to help doctors better diagnose pancreatic cancer. If you are suspected of having pancreatic cancer or a recurrence, this study may help confirm or clarify your diagnosis.
TurkuAges 18–85 - NCT07098780RecruitingPhase 4
Tranexamic Acid to Prevent Bleeding in Weight Loss Surgery
This trial tests whether a medicine called tranexamic acid (TXA) can reduce bleeding during weight loss surgery. If you are having a sleeve gastrectomy or mini-gastric bypass, taking TXA may lower your risk of hemorrhagic events.
Karachi, SindhAges 18–60 - NCT07102043Enrolling by invitation
Glucose study in cystic fibrosis related diabetes
This study looks at how the body handles sugar in people with cystic fibrosis related diabetes. Researchers want to learn more about glucose metabolism to improve care for people with CFRD.
Birmingham, AlabamaAges 21–75 - NCT07096908RecruitingPhase 4
Tirzepatide for weight loss in type 1 diabetes
This study tests a medication called tirzepatide for people with type 1 diabetes who also have overweight or obesity. Tirzepatide may help with weight loss and blood sugar control, and you'll use a continuous glucose monitor throughout the study.
Kuwait City, SharqAges 21 years+ - NCT07100288Recruiting
Study of the ovary ligament in ovarian cancer patients
This trial looks at a specific ligament near the ovary in patients with epithelial ovarian cancer to better understand the disease. It is for people who had surgery with no cancer left behind.
Las Palmas de Gran CanariaAges 18 years+ - NCT07104812RecruitingPhase 2
Testing low-dose osilodrostat for mild cortisol excess
This study tests whether a low dose of the drug osilodrostat can help people with mild cortisol excess (MACS) caused by benign adrenal tumors. It may improve related health problems like high blood pressure, diabetes, or bone thinning.
Rochester, MinnesotaAges 18 years+ - NCT07102264Recruiting
Ultrasound test for thyroid stiffness before surgery
This study tests a new, non-invasive ultrasound method to measure how compressible (squishy) your thyroid gland is, before you have surgery to remove it. The goal is to see if this safe, painless measurement can help surgeons plan better.
BernAges 18 years+ - NCT07096934RecruitingPhase 1/Phase 2
Testing a new cell treatment for stubborn diabetic foot ulcers
This trial tests a new treatment using special skin cells grown into tiny spheres (spheroids) to help heal diabetic foot ulcers that have not healed with standard care. It aims to see if this treatment is safe and works better than usual care.
Coffs Harbour, New South WalesAges 18–80 - NCT07099456Recruiting
Fertility and sexual health in adrenal gland disorder
This study looks at fertility and sexual function in people with congenital adrenal hyperplasia (CAH), a condition affecting hormone production. It aims to understand how CAH impacts these areas.
Rome, ItalyAges 18–65
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.