Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,627 recruiting studies in this area right now.
By phase
- Not applicable5,353
- Phase 2607
- Phase 1557
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida166
- Texas158
- Massachusetts151
- New York144
- Colorado115
- Pennsylvania114
Recruiting studies7,627 total
- NCT06976658RecruitingPhase 2
Glucokinase Activator for GCK-MODY Diabetes
This trial tests an experimental pill (a glucokinase activator) in adults with a specific genetic form of diabetes called GCK-MODY. The study aims to see if the pill can help control blood sugar without causing dangerously low sugar levels.
Hong KongAges 18–74 - NCT06981663Recruiting
Fibers and probiotics for uric acid levels
This study looks at how certain fibers and probiotics might affect uric acid levels in your body. You'll provide a stool sample, and it will be tested in a lab to see if these ingredients can help lower uric acid.
ÖrebroAges 18–80 - NCT06972719Recruiting
Hormone therapy after ovary removal for BRCA mutation carriers
This study looks at giving hormone therapy after ovary and fallopian tube removal in women with a BRCA mutation. The goal is to help manage menopause symptoms while you are still premenopausal.
Chapel Hill, North CarolinaAges 19–50 - NCT06980103Recruiting
Decision aid for RAI in thyroid cancer
This trial offers a decision aid to help you choose whether to have radioactive iodine (RAI) treatment after thyroid cancer surgery. You may qualify if you have intermediate-risk thyroid cancer and haven't yet made a decision about RAI.
Washington D.C., District of ColumbiaAges 18 years+ - NCT03298334RecruitingPhase 1/Phase 2
Testing vaginal bacteria transfer to newborns after C-section
This study looks at whether they can safely place “healthy vaginal bacteria” from the mother into the newborn after a scheduled C-section, and whether it improves the baby’s health. It only enrolls certain mothers and babies based on infection testing and other health factors.
Falls Church, VirginiaAges birth–50 years - NCT04246944Recruiting
Induced membrane bone repair study in critical defects
This study looks at how a specific bone-repair technique (called induced membrane reconstruction) works in people with large “critical-sized” bone defects. It may help doctors understand the results and properties of this method in both children and adults.
AmiensAges 9 months–60 years - NCT06858683Recruiting
Time-restricted eating study for people with obesity
This study tests if eating only within a certain time window each day can improve immune function in people with obesity who are planning bariatric surgery. You would follow a time-restricted eating plan for 10-12 weeks before your surgery to see how it affects your health.
BarcelonaAges 18–64 - NCT06264570Recruiting
Personalized supplements for high homocysteine and cholesterol
This study tests a personalized approach based on your genes to choose the right natural supplements for people with high homocysteine and high LDL cholesterol. It aims to help lower these levels safely.
Novosibirsk, Novosibisk RegionAges 18–80 - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Birmingham, AlabamaAges 18–50 - NCT06970106RecruitingPhase 1/Phase 2
Study of PYC-001 eye injections for people with a type of inherited optic nerve disease
This trial tests a new medicine called PYC-001, given as an injection into the eye, for people with a specific genetic form of vision loss called autosomal dominant optic atrophy (ADOA). It aims to see if the treatment is safe and could help protect or improve vision.
Sydney, New South WalesAges 18 years+ - NCT06454617Recruiting
Comparing bone density measures from routine CT scans
This study looks at simpler ways to measure bone density from routine CT scans of the lower back or abdomen. If you are already getting a CT scan, the researchers will use those images to check your bone health without extra tests or radiation.
Bologna, BoAges 18 years+ - NCT06963268RecruitingPhase 3
Testing sentinel lymph node surgery for early ovarian cancer
This study tests a way to check for cancer spread in the lymph nodes of the pelvis during surgery for early-stage ovarian cancer. It uses a special dye and tracer to find the first lymph node that drains from the tumor.
Valencia, ValenciaAges 18 years+ - NCT06969833Recruiting
Study of Ovarian, Peritoneal, or Fallopian Tube Cancer
This study will collect medical information from people with advanced ovarian, peritoneal, or fallopian tube cancer. The goal is to learn more about these cancers and improve future treatments.
LilleAges 18 years+ - NCT06964009RecruitingPhase 1
New drug plus paclitaxel for resistant ovarian cancer
This trial tests a new drug called DT2216 combined with the chemotherapy drug paclitaxel for ovarian cancer that has stopped responding to platinum-based chemo. The goal is to see if this combination can shrink or slow the cancer, and to find a safe dose.
Boston, MassachusettsAges 18 years+ - NCT06969235Recruiting
Family weight loss program for teens
This study tests a family-based weight loss program for teens ages 13-17 who have overweight or obesity. It looks at how thinking skills (like planning and focus) affect the program's success.
Columbia, MissouriAges 13–17 - NCT06967558RecruitingPhase 2
GLP-1 hormone role in prediabetes
This study looks at how a hormone called GLP-1, made in the pancreas, affects blood sugar levels in people with borderline high blood sugar (prediabetes). It may help find new ways to prevent diabetes.
Rochester, MinnesotaAges 25–70 - NCT06968936Recruiting
Long-term outcomes of pre-surgery iron therapy
This study looks at long-term results of giving iron before major heart surgery to people with low iron levels. It aims to see if this treatment helps recovery and outcomes.
Hangzhou, ZhejiangAges 18–85 - NCT06970353RecruitingPhase 2
Study of tunlametinib for NRAS-mutant advanced thyroid cancer
This trial tests a targeted drug (tunlametinib) for advanced thyroid cancer that has a specific genetic change called NRAS mutation. It may help people whose cancer is not responding to standard treatments like radioactive iodine.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06971952Recruiting
Tuberculosis study in rural malnourished communities
This study looks at how TB affects people in rural areas who may also be malnourished. It aims to understand and improve TB care for these communities.
Haydom, Manyara RegionAges Any age - NCT06966258Recruiting
Heart health program for Black women in Birmingham
This trial tests a program called Inspire HER, which aims to improve heart and emotional health for Black women with early-stage cardiovascular-kidney-metabolic syndrome. You may qualify if you have this condition and live in the Birmingham area.
Birmingham, AlabamaAges 30–79 - NCT06971146Recruiting
Nurse-led telehealth for gout management
This trial tests whether nurse-led telehealth visits can help people with gout maintain healthy urate levels. If you have gout and are already on medication like allopurinol, this study may offer a convenient way to manage your condition from home.
AarhusAges 18 years+ - NCT06969807RecruitingPhase 2
Stem cells for diabetic kidney disease
This trial tests whether a type of stem cell called mesenchymal stromal cells (Amimestrocel) can help people with diabetic kidney disease. It aims to see if the treatment is safe and can improve kidney function.
Beijing, Beijing MunicipalityAges 18–80 - NCT06966934Recruiting
Nasal airway and oxygen for stomach scope in obesity
This trial tests whether a breathing tube placed in the nose (nasopharyngeal airway) combined with high-flow oxygen can improve safety during painless gastroscopy in people with obesity. It may help you breathe better while sedated.
NanjingAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,627 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,981 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.