Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT04234724Recruiting
Study of how ANGPTL3 gene variants affect body functions
This study looks at how different ANGPTL3 gene versions may change normal body measurements (such as blood and metabolism). It may help researchers understand why these genetic differences affect health, especially related to fats (lipids) in the body.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05009082RecruitingPhase 3
Niraparib alone or with bevacizumab for advanced ovarian cancer
This trial studies whether niraparib works better when combined with bevacizumab after chemotherapy and surgery for advanced ovarian, fallopian tube, or peritoneal cancer. If you qualify, you may help researchers find a treatment plan that controls the cancer for longer.
AmbergAges 18 years+ - NCT06256614Recruiting
Washed stool transplant for type 1 diabetes
This trial tests if a washed microbiota transplant (a processed stool transplant from healthy donors) can help people with type 1 diabetes. It aims to see if this treatment can improve blood sugar control or reduce the need for insulin.
Nanjing, JiangsuAges 3–100 - NCT06455371Recruiting
Personalized Levothyroxine Dosing After Thyroid Removal
This study tests a personalized way to dose levothyroxine (thyroid hormone) after total thyroid removal. It aims to find the right dose for each patient, improving energy and well-being.
BergenAges 18 years+ - NCT06469281RecruitingPhase 1
A new immune cell therapy for recurring ovarian cancer
This early-phase trial tests a new immune cell therapy called 27T51, which targets a protein called MUC16 found on ovarian cancer cells. The study is for people with recurrent or treatment-resistant ovarian, primary peritoneal, or fallopian tube cancer to see if the therapy is safe and works when given alone or with other treatments.
Boston, MassachusettsAges 18 years+ - NCT06463028RecruitingPhase 2
Targeted pills plus chemo for advanced endometrial cancer
This trial tests a combination of two targeted pills (sapanisertib and serabelisib) with standard chemo (paclitaxel) for endometrial cancer that has come back or spread. A substudy also looks at combining these drugs with a special diet that lowers insulin levels.
La Jolla, CaliforniaAges 18 years+ - NCT06465810Recruiting
Observational study for ATTR amyloidosis patients
This study follows patients with ATTR amyloidosis over time to understand how the disease affects them. It does not test a new treatment—instead, it asks you to fill out questionnaires about your health and symptoms to help doctors learn more about the condition.
La Jolla, CaliforniaAges 18–130 - NCT06466135RecruitingPhase 2
Study of WAL0921 for glomerular kidney diseases
This study tests a new drug called WAL0921 for people with certain types of kidney disease. The goal is to see if it can help protect kidney function.
Los Angeles, CaliforniaAges 18–75 - NCT06464510RecruitingPhase 3
Treating sepsis with norepinephrine plus early vasopressin
This trial tests whether giving a second medicine called vasopressin early (along with norepinephrine) helps people with sepsis and low blood pressure better than waiting to use vasopressin only if norepinephrine doesn't work. It may improve blood pressure control and reduce the need for strong medicines.
Caxias do Sul, Rio Grande do SulAges 18 years+ - NCT06463483Recruiting
Automated Insulin Delivery for People with Advanced Kidney Disease
This trial tests an automated insulin pump system for people with diabetes who also have advanced kidney disease. It may help manage blood sugar more easily.
LondonAges 18–70 - NCT06470295RecruitingEarly Phase 1
C-peptide's effect on low blood sugar response
This study tests whether C-peptide (a substance made by the pancreas) can help your body respond better to low blood sugar (hypoglycemia). It's a very early trial for people without certain health conditions.
Cincinnati, OhioAges 18–40 - NCT06476184RecruitingPhase 3
Adjusted chemo dosing for hard-to-treat ovarian cancer
This trial tests a different way of giving chemotherapy to people with advanced ovarian cancer that didn't respond well to initial treatment. The goal is to see if changing the dose and schedule can improve outcomes.
AngersAges 18 years+ - NCT06464497Recruiting
Whole foods for teens with obesity pilot study
This study tests whether replacing processed foods with whole foods (like fruits, vegetables, and whole grains) for 8 weeks can help reduce body fat in teens with obesity. Both the teen and a parent or caregiver will learn to prepare and eat healthier meals together.
Nashville, TennesseeAges 10 years+ - NCT06469437Recruiting
Geriatric check for older adults with type 2 diabetes
This study looks at how a full health check for older adults with type 2 diabetes can help doctors choose the best treatment plan. It aims to improve care for people 60 and older.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT06462170Recruiting
Measuring insulin production in type 2 diabetes
This study tests how well your body makes insulin by having you drink a Boost shake and checking your blood. It's designed for people with type 2 diabetes who are not yet on insulin.
Ottawa, OntarioAges 18 years+ - NCT06474598RecruitingPhase 2
Test of MTX228 for type 1 diabetes with some insulin
This study tests a new medication, MTX228, to see if it can help people with type 1 diabetes who still make some insulin. It may slow the loss of your own insulin production and improve blood sugar control.
Edmonton, AlbertaAges 18–65 - NCT06466161Recruiting
Testing a new blood pressure measurement method in pregnant patients
This study is testing a new way to measure blood pressure on your forearm and upper arm. It aims to see if this method works well for pregnant patients, especially those with high blood pressure conditions.
Chicago, IllinoisAges 18 years+ - NCT06461208RecruitingPhase 3
Fecal transplant for people with cirrhosis
This trial tests whether transplanting healthy gut bacteria (from donor stool) can improve outcomes in people with cirrhosis. If you have mild to moderate cirrhosis, you may be able to join.
BasildonAges 18 years+ - NCT06463223Enrolling by invitation
Liver imaging study for children with obesity
This study uses MRI scans to look at the livers of children with obesity, to find early signs of liver problems. It may help doctors understand how to protect the liver in children.
Gothenburg, Västra Götaland CountyAges 9–14 - NCT06471582Recruiting
How meal timing affects your menstrual cycle
This study looks at how the timing of energy from food affects your menstrual cycle in women who exercise regularly. It may help understand how to support healthy periods for active women.
Colorado Springs, ColoradoAges 18–40 - NCT06473584Recruiting
Diabetes & Pre-diabetes Study in Réunion Island
This study checks how many people on Réunion Island have diabetes or early signs of it (pre-diabetes). It aims to learn more about these conditions in your community to improve care and prevention.
Saint-DenisAges 18–75 - NCT06461065Recruiting
Brain development in children with type 1 diabetes using an automated insulin system
This study looks at how an automated insulin delivery system affects brain development in young children with type 1 diabetes. It may help understand if better glucose control early on benefits thinking and learning.
ParisAges 5–8 - NCT06468215Recruiting
Fertility-sparing treatment for early stage 2 endometrial cancer
This study tests a way to treat early-stage endometrial cancer without removing the uterus, so you can still have a chance to carry a pregnancy. It’s for women under 45 with a grade 2 tumor that hasn’t grown into the womb muscle.
Beijing, Beijing MunicipalityAges Up to 45 years - NCT06476795Recruiting
Grape pomace from chardonnay for heart and gut health in postmenopausal women
This study tests if consuming a powder made from chardonnay grape pomace (the leftover skins and seeds from winemaking) can improve gut and heart health in postmenopausal women. You may be a good fit if you are between 45-70, have gone through menopause, and have higher levels of blood fats called triglycerides.
Davis, CaliforniaAges 45–70
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.