Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,051 recruiting studies in this area right now.
By phase
- Not applicable2,997
- Phase 21,057
- Phase 1792
- Phase 1/Phase 2437
- Phase 3436
- Phase 4234
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma327
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis132
- Type 1 Diabetes130
- Atopic Dermatitis125
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia95
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Diabetes Mellitus, Type 163
- Hodgkin Lymphoma63
- Leukemia63
- Mantle Cell Lymphoma62
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic49
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California496
- Maryland200
- Alabama178
- Florida149
- Arizona147
- Massachusetts116
- New York116
- Texas112
- Illinois83
- Colorado82
Recruiting studies6,051 total
- NCT05681975Recruiting
Test whether antibodies relate to food reaction symptoms
This study looks at adults who have symptoms they believe are caused by reactions to foods. Researchers will test immune blood markers (antibodies) to better understand what may be driving these symptoms and whether that information could help people in the future.
MadridAges 18–80 - NCT04924998Recruiting
Study for AL-CM treatment in adults at one hospital
This study is looking at a treatment approach for people diagnosed with AL-CM at a specific hospital. It may help researchers understand whether the treatment is safe and effective for patients like you.
Hangzhou, ZhejiangAges 18–80 - NCT03215836Recruiting
Study obesity and metabolism in adults with asthma
This study looks at how weight and blood-sugar/fat changes in the body may affect the airways in people with asthma. You may be asked to complete breathing tests and possibly an airway procedure (bronchoscopy) to help researchers compare groups.
Aurora, ColoradoAges 18–65 - NCT02883335Recruiting
MS registry for people living in Lorraine
This study is a registry that collects information from people who have multiple sclerosis (MS). It helps researchers better understand MS in the Lorraine region and may guide future care.
NancyAges Any age - NCT04657783Recruiting
French cohort study of people with type 1 diabetes
This study follows people with type 1 diabetes in France to better understand the condition over time. It may help researchers improve future care, especially for how type 1 diabetes starts and is managed from early diagnosis onward.
ParisAges 6–100 - NCT02653079Recruiting
Blood testing and low-dose radiation for painful joint conditions
This study collects blood samples and treats certain painful joint/soft-tissue problems with low-dose local radiation therapy. It aims to understand disease features and how patients may respond to this treatment.
Erlangen, BavariaAges 18 years+ - NCT05036850Recruiting
Kidney patient research network follow-up study
This trial is for people with a primary (main) kidney disease who can regularly see a kidney doctor. It sets up and includes patients for possible interventional (active) research studies, which may help improve kidney care for future patients.
Beijing, Beijing MunicipalityAges 2 years+ - NCT05643092Recruiting
Testing scans and biomarkers for CAR T neurotoxicity risk
This study uses blood tests and brain imaging to better understand and predict nerve-system side effects that can happen after CAR T-cell treatment. It may help doctors spot people at higher risk sooner and guide safer care.
Shijiazhuang, HebeiAges 18–80 - NCT05648019RecruitingPhase 2
CD19 CAR T-cell therapy for tough B-cell blood cancers
This Phase 2 study tests a one-time CAR T-cell treatment aimed at CD19, a target found on many B-cell leukemias and lymphomas. It’s for people whose disease has come back or hasn’t responded to prior treatments, or who can’t have a stem cell transplant.
SingaporeAges birth–70 years - NCT05772611Recruiting
Study of immune responses in brain autoimmune and nerve syndromes
This study looks at how the immune system works in certain neurological conditions, including autoimmune encephalitis and related nerve disorders. Researchers may use blood and/or spinal fluid samples, especially when antibodies are present or can’t be found, to better understand what’s driving the illness.
LyonAges 18 years+ - NCT03048201Recruiting
Total Knee Replacement Registry Study for a Specific Knee Implant
This study tracks outcomes for people getting a total knee replacement using a specific knee implant system. It may help doctors understand which patients do best and how the implant performs over time.
Rancho Mirage, CaliforniaAges 22 years+ - NCT05521802RecruitingPhase 1/Phase 2
Testing a new CAR-T therapy for relapsed myeloma
This Phase 1/2 study tests C-CAR088, a lab-made immune therapy, in people with multiple myeloma that has come back or did not respond. It is for patients who have already had several standard treatments and whose disease is still measurable.
TianjinAges 18 years+ - NCT05785793Recruiting
Autoimmune hepatitis study for people in China
This study follows people with autoimmune hepatitis (a condition where the immune system attacks the liver) and requires key blood test results at diagnosis. It may help doctors better understand this disease and how it progresses in patients in China.
Shanghai, Shanghai MunicipalityAges 14 years+ - NCT05259904RecruitingPhase 2
L-citrulline supplement for deployment-related asthma symptoms
This trial studies whether an L-citrulline supplement can improve asthma control in people who developed persistent asthma symptoms after military deployment. If you qualify, you may be asked to track symptoms and breathing test results to see if the supplement helps.
Denver, ColoradoAges 18–70 - NCT05231135Recruiting
Registry study for lymphoma in people living with HIV
This study keeps a registry (a protected health record database) of adults with lymphoma who also have HIV. The goal is to better understand lymphoma in people with HIV and how they’re diagnosed and followed over time.
Munich, Select One OptionAges 18 years+ - NCT04920617RecruitingPhase 2
Vaccine plus pembrolizumab, with or without low-dose chemo
This Phase 2 study tests whether a cancer vaccine called DPX-Survivac, along with pembrolizumab (an immune medicine), can help shrink diffuse large B-cell lymphoma (DLBCL) that has come back or not responded. It also looks at whether adding intermittent low-dose cyclophosphamide (a low-dose chemotherapy) improves results.
Fountain Valley, CaliforniaAges 18 years+ - NCT02169518Recruiting
Testing blood fat markers in diabetes and heart health
This study measures how certain blood “fat” markers relate to blood sugar control and inflammation. It may help researchers understand risk factors for heart disease in people with type 1 or type 2 diabetes, pre-diabetes, and people preparing for weight-loss surgery.
Manchester, LancashireAges 20–75 - NCT05797272Recruiting
In-utero stem cell treatment for Bart’s hydrops
This trial studies whether giving hematopoietic (blood-forming) stem cells while the baby is still in the womb can treat fetuses with Bart’s hydrops fetalis syndrome. It aims to improve outcomes after prenatal intervention in carefully selected pregnancies.
ShatinAges 18 years+ - NCT04096794Recruiting
Smartphone-based research study for people with type 1 diabetes
This study is a multi-site project designed for people who have type 1 diabetes and can use a smartphone app (WeChat or a similar app). It aims to collect research information in a way that’s easier to follow day to day, which may help improve future care for type 1 diabetes.
Changsha, HunanAges Any age - NCT05834855RecruitingPhase 3
Rituximab versus ocrelizumab for relapsing multiple sclerosis
This Phase 3 trial compares two similar immune therapies—rituximab and ocrelizumab—to see if rituximab works about as well for relapsing multiple sclerosis. It may help you and researchers understand which option is equally effective and safe for preventing relapses and disease activity.
AmsterdamAges 18 years+ - NCT04654923Recruiting
Survey of allergic reactions around anesthesia
This study collects information about people who had an allergic-type reaction around surgery or anesthesia. It aims to understand how often these reactions happen and to improve future care. You may be able to join if your reaction fits the time window and you agree to use your records.
StrasbourgAges 7 years+ - NCT05848570Recruiting
Digital program for reducing HIV risk in SGM youth
This trial tests a digital health program (available with limited in-person contact) to help SGM young people reduce their risk of HIV. You may be a good fit if you’re in the right age range and have had certain types of sex in the last 6 months.
Chicago, IllinoisAges 13–34 - NCT04629586Recruiting
T1D Exchange registry for people with type 1 diabetes
This trial registry collects information about people living with type 1 diabetes to help researchers better understand the condition. It may help by allowing future studies and improving how care is studied and planned.
Boston, MassachusettsAges Any age - NCT05840575Recruiting
Study of thinking changes in young people during cancer treatment
This study looks at how thinking and memory may change in children and young adults after a new cancer diagnosis, especially around chemotherapy. It may help doctors better understand and track brain-related side effects early.
CopenhagenAges 7–29
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,051 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,083 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.