Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07222696Recruiting
Health coaching for rheumatoid arthritis to improve mental wellbeing
This study tests if working with a health coach (a trained peer) can help people with rheumatoid arthritis feel better emotionally, especially if they are dealing with depression or anxiety. You would meet with a coach remotely using your phone or computer.
New York, New YorkAges 18 years+ - NCT07230015Recruiting
Imagery and balance training for MS
This study tests if combining mental practice of movements with balance exercises helps people with relapsing-remitting MS who have mild balance problems and dizziness. It aims to improve stability and reduce vertigo.
Istanbul, Beykoz/İstanbulAges 18–45 - NCT07225868Recruiting
Coaching to boost cognitive rehab in MS
This trial tests if coaching in goal-directed behavior can improve cognitive rehabilitation for people with relapsing-remitting or secondary progressive MS. It aims to help patients better manage daily tasks and thinking challenges.
Buffalo, New YorkAges 18–65 - NCT07222111Recruiting
Dried plums for immune health in postmenopausal women
This study tests whether eating dried plums every day can improve immune function in women after menopause. Participants will eat dried plums and provide stool samples at four times during the study.
Indianapolis, IndianaAges 60–75 - NCT07224100RecruitingPhase 2
Chemo plus targeted drug for newly diagnosed Ph+ ALL
This trial tests a combination of chemotherapy drugs (EPOCH) plus a targeted therapy (ponatinib) for patients with a specific type of acute lymphoblastic leukemia (Ph+ ALL). Some participants also get rituximab if their leukemia cells have a certain marker (CD20). The goal is to see how well this treatment works as a first therapy.
Seattle, WashingtonAges 18 years+ - NCT07221643Recruiting
Carotenoids, skin health and immune aging study
This study looks at how natural compounds in the skin called carotenoids relate to immune changes as we age. It compares younger and older healthy adults to understand aging better.
Redwood City, CaliforniaAges 18 years+ - NCT07222579RecruitingPhase 2
Study of blinatumomab injection for a rare leukemia type
This trial tests a new way to give blinatumomab (a drug that helps your immune system fight cancer) as a shot under the skin for a rare leukemia called MPAL. It includes three different groups of patients depending on their treatment history.
Morgantown, West VirginiaAges 18 years+ - NCT06910527Recruiting
Testing blood and urine for kidney rejection signs
This study is for people with a kidney transplant who are in the hospital for a biopsy because their doctor suspects rejection. Researchers want to see if a simple blood or urine test can detect rejection, which might make future biopsies less necessary.
RouenAges 18 years+ - NCT06907056RecruitingPhase 4
A study on a simpler HIV medication combination
This study tests if a two-drug HIV regimen (darunavir/cobicistat plus lamivudine) works as well as a standard three-drug regimen in men whose HIV is already well-controlled. If effective, this could mean taking fewer medications.
Mexico City, Mexico CityAges 18–70 - NCT07224373RecruitingPhase 1
A study of AZD0120 for multiple sclerosis
This trial tests an experimental drug called AZD0120 in adults with multiple sclerosis. It is designed for people with relapsing or progressive forms of MS who have not responded well to other treatments or have active disease.
Tucson, ArizonaAges 18–60 - NCT07228026Recruiting
Device to Monitor Asthma by Measuring Nitric Oxide in Breath
This trial tests a handheld device that measures nitric oxide in your breath to see if it can help monitor asthma. You may qualify if you have uncontrolled asthma and can use the device at home.
Stockton, CaliforniaAges 5–100 - NCT07225504RecruitingPhase 3
Study of remibrutinib for secondary progressive multiple sclerosis
This trial tests an oral medication called remibrutinib to see if it can slow disability progression in people with secondary progressive multiple sclerosis (SPMS). You might join if you have had MS for a while, your symptoms have worsened over the past year, and you haven't had any recent relapses.
Birmingham, AlabamaAges 18–65 - NCT07229950RecruitingPhase 2
Experimental tablet for moderate to severe Ulcerative Colitis
This trial tests an experimental tablet, HRS-7085, for people with moderate to severe Ulcerative Colitis who haven't gotten enough help from standard treatments. The goal is to see if the drug can reduce inflammation and improve symptoms.
Chengdu, SichuanAges 18–75 - NCT07227311RecruitingPhase 2
Belantamab mafodotin combinations for relapsed multiple myeloma
This trial tests a new drug called belantamab mafodotin (a targeted antibody therapy) combined with standard treatments for multiple myeloma that has come back or stopped responding. It looks at three different drug combinations to see which works best for people who have had 1 or 2 prior treatments.
Los Alamitos, CaliforniaAges 18 years+ - NCT07221838RecruitingPhase 4
Steroid Tapering Study for Myasthenia Gravis on Ravulizumab
This study is for people with generalized myasthenia gravis who are already on ravulizumab and a daily steroid. It aims to see if the steroid dose can be safely lowered over time.
Chicago, IllinoisAges 18 years+ - NCT07221500RecruitingPhase 2
Study of NX-5948 for advanced CLL or SLL
This trial tests an experimental drug called NX-5948 for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or not responded to prior treatments. It's for those who have already tried a BTK inhibitor and a BCL-2 inhibitor.
Phoenix, ArizonaAges 18 years+ - NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Los Angeles, CaliforniaAges 6–17 - NCT07221565Enrolling by invitationPhase 1/Phase 2
Immune mapping trial for autoimmune conditions
This trial is testing a new way to map the immune system using electromagnetic signals and forecast how your body's immune system will respond. It may help people with autoimmune conditions like lupus or rheumatoid arthritis find new treatment options.
New York, New YorkAges Any age - NCT07224672RecruitingPhase 2
Study of a drug combo for newly diagnosed AL amyloidosis
This trial tests a combination of four drugs (belantamab mafodotin, cyclophosphamide, bortezomib, and dexamethasone) for people newly diagnosed with AL amyloidosis who cannot have a stem cell transplant. The goal is to see if this combination is safe and effective at stopping the abnormal proteins from damaging your organs.
Rochester, MinnesotaAges 18 years+ - NCT07228325Enrolling by invitationPhase 1/Phase 2
Comparing a new epinephrine injector to EpiPen in adults with allergies
This study tests a new epinephrine auto-injector (FMXIN002) compared to the standard EpiPen in people with a history of hay fever or seasonal allergies. The goal is to see if the new device works just as well and is safe in a controlled clinic setting.
MississaugaAges 18–55 - NCT07226843RecruitingPhase 1
Study of a new drug for adults with certain blood cancers
This trial tests a new drug, LY4584180, for adults with several types of non-Hodgkin lymphoma who have already had at least two prior treatments. The goal is to see if the drug can help shrink tumors and stop the cancer from growing.
Scottsdale, ArizonaAges 18 years+ - NCT07229742RecruitingPhase 2
Study of SHR-2173 for active lupus nephritis
This trial tests a new medicine called SHR-2173 for people with active lupus nephritis, a kidney inflammation caused by lupus. The goal is to see if it is safe and effective.
Nanjing, JiangsuAges 18–70 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Santa Barbara, CaliforniaAges 1–35 - NCT07222332RecruitingPhase 3
Baricitinib for new type 1 diabetes to save insulin-making cells
This trial tests if baricitinib, a pill that calms the immune system, can protect the remaining insulin-making cells in people newly diagnosed with type 1 diabetes. If it works, you might keep making some of your own insulin longer.
Aurora, ColoradoAges 1–35
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.