Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,062 recruiting studies in this area right now.
By phase
- Not applicable3,004
- Phase 21,058
- Phase 1794
- Phase 1/Phase 2439
- Phase 3436
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis329
- Multiple Myeloma328
- Asthma193
- Lymphoma178
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis124
- Systemic Lupus Erythematosus119
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases77
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca63
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center48
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California497
- Maryland199
- Alabama177
- Florida152
- Arizona148
- Massachusetts117
- New York116
- Texas112
- Colorado82
- Illinois82
Recruiting studies6,062 total
- NCT07143617Recruiting
Safety study of STR-P004 for lupus and inflammatory muscle disease
This trial tests the safety of a new treatment called STR-P004 for people with systemic lupus erythematosus (SLE) or certain inflammatory muscle diseases that have not improved with standard therapies. It may be an option if your condition is hard to control.
BeijingAges 18 years+ - NCT07137494RecruitingPhase 1
CAR T-cell therapy for CNS lymphoma
This trial tests a new type of CAR T-cell therapy (MB-CART19.1) for people with central nervous system lymphoma (CNSL) that has come back or not responded to treatment. It aims to see if this therapy can help treat the lymphoma in the brain or spinal fluid.
Basking Ridge, New JerseyAges 18 years+ - NCT07135583Recruiting
Breathing recovery after spinal cord injury
This study tests non-invasive treatments to help people with chronic spinal cord injury improve their breathing. It may be a good fit if you have had a spinal cord injury for at least a year and have weak breathing muscles.
Philadelphia, PennsylvaniaAges 18–70 - NCT07138729Recruiting
Imaging test for rheumatoid arthritis inflammation
This trial tests a new imaging scan (SPECT) that uses a special tracer (99mTc-TCR-FAPI) to see inflammation in the joints of people with rheumatoid arthritis. It aims to help doctors better understand and track disease activity.
Beijing, Beijing MunicipalityAges 18–75 - NCT07142681Recruiting
How adults' diets change when caring for a child with new type 1 diabetes
This study looks at how the eating habits of adults change when they care for a child newly diagnosed with type 1 diabetes. The goal is to understand what you go through and find better ways to support families.
BarcelonaAges 18 years+ - NCT07142473Recruiting
Mastocytosis Registry from Childhood to Adulthood
This registry collects information from people with mastocytosis (a condition where too many mast cells build up in the skin or organs) who are treated at a specific clinic in Italy. The goal is to better understand how the disease changes over time from childhood to adulthood.
Pavia, PaviaAges 6 years+ - NCT07139899Recruiting
Mucus Plugs and Lung MRI in Severe Asthma
This study is looking at how mucus plugs in the airways affect lung function in people with severe asthma. If you are about to start a new injectable asthma treatment (dupilumab, tezepelumab, or benralizumab), you may be able to join and get a special type of lung MRI to see how your lungs are doing.
Durham, North CarolinaAges 18–65 - NCT07137624Recruiting
Can thinking about walking help MS patients?
This study tests whether imagining or watching walking movements can improve walking ability in people with multiple sclerosis. It focuses on low-risk, non-invasive mental exercises that may help retrain the brain and muscles.
AnkaraAges 18 years+ - NCT07144696Recruiting
Study to improve metabolic health in type 1 diabetes
This study offers a structured education course and regular checkups to help adults with type 1 diabetes better manage their blood sugar and overall health. Participants will learn about their condition and receive support to improve metabolic indicators.
BeijingAges 18 years+ - NCT07136025Recruiting
Finding treatable traits in severe asthma for personalized care
This study aims to identify specific treatable traits in people with severe asthma and build a personalized treatment plan. It will help doctors understand which treatments might work best for you based on a detailed evaluation.
Beijing, Beijing MunicipalityAges 18–80 - NCT06959732RecruitingPhase 2
Zanubrutinib with G-CVP for untreated follicular lymphoma
This trial tests a combination of targeted therapy (zanubrutinib) and chemotherapy (G-CVP) for people with follicular lymphoma who have not had treatment before. It aims to see if this combination is safe and effective.
Beijing, Beijing MunicipalityAges 18–80 - NCT06693479Recruiting
Using a feedback device to help manage shoulder pain at work
This study tests whether a feedback device can help people with work-related shoulder pain manage their symptoms. You may qualify if you have shoulder pain from rotator cuff issues, arthritis, or rheumatoid arthritis and work full-time.
Québec, QuebecAges 18 years+ - NCT07135466RecruitingPhase 1/Phase 2
Anti-CD22 CAR T-cell therapy for B-cell blood cancers
This trial tests a new treatment using your own immune cells (T-cells) that are modified to find and attack cancer cells with a marker called CD22. It is for people with B-cell blood cancers that have come back or not responded to at least two prior treatments, including a type of immunotherapy called CAR T-cell therapy.
Ramat Gan, GAges 1–80 - NCT07128966Recruiting
Collect biospecimens and health data for research
This study collects blood, saliva, or other biospecimens and health information from people with certain medical conditions. Your samples and data will help researchers better understand diseases and develop new treatments.
Lexington, MassachusettsAges 18–90 - NCT07132112RecruitingEarly Phase 1
GT719 injection for moderate to severe autoimmune disease
This trial tests an experimental cell therapy (GT719) for people with autoimmune diseases like lupus, inflammatory myositis, or systemic sclerosis that have not responded well to other treatments. It aims to see if this therapy can help control the disease.
Nantong, JiangsuAges 18–65 - NCT07132567Recruiting
Studying safety and effectiveness of Poteligeo for certain skin lymphomas
This study is tracking the safety and effectiveness of a drug called Poteligeo (mogamulizumab) for adults with mycosis fungoides or Sézary syndrome who have already tried at least one body-wide treatment. It is a post-market surveillance study, meaning the drug is already approved, and doctors are gathering real-world information about how well it works and any side effects.
Busan, Busan Metropolitan CityAges 19 years+ - NCT06035328Recruiting
Comparing different maintenance doses for wheat allergy oral immunotherapy
This study tests whether taking a maintenance dose of wheat oral immunotherapy once or twice a week is more effective for children with wheat allergy. It aims to find the best schedule to keep them protected from allergic reactions.
Bangkoknoi, BangkokAges 5–18 - NCT07127926RecruitingPhase 1
Belumosudil pill vs crushed pill study for chronic GVHD
This trial tests whether crushing belumosudil tablets changes how the drug works in people with chronic graft-versus-host-disease (GVHD), a complication after a stem cell transplant. It helps doctors know if taking crushed pills is as effective as whole tablets.
Houston, TexasAges 18 years+ - NCT07126431Recruiting
Study of hard-to-treat rheumatoid arthritis
This study is observing people with a hard-to-treat form of rheumatoid arthritis (RA). Researchers want to understand what treatments and outcomes are like for people whose RA doesn't get better with standard medications like methotrexate.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07126028Enrolling by invitation
Quality of life in kids after MIS-C
This study looks at how children feel and live their daily lives after recovering from MIS-C (a severe inflammatory condition linked to COVID-19). It compares them to healthy children of the same age and gender to see if there are any lasting effects.
Rijeka, Primorje-Gorski Kotar CountyAges 1 month–18 years - NCT07127835Recruiting
Comparing nurse-led and allergist-led penicillin allergy testing
This study compares two ways of evaluating penicillin allergies: one where a nurse works with an allergist, and another where only an allergist does the evaluation. If you have a penicillin allergy on record, this trial may help find out which approach works better.
Hong KongAges 18 years+ - NCT07134686Recruiting
Combined lung and ear-nose-throat care for asthma and sinusitis
This trial tests if seeing a lung specialist and an ear-nose-throat doctor together in one visit helps people with asthma and chronic sinusitis (with nasal polyps) feel better than seeing each specialist separately. You may qualify if your asthma or sinusitis is not well-controlled and you've used steroid pills in the past year.
MarseilleAges 18 years+ - NCT07135219Enrolling by invitationEarly Phase 1
Study of cizutamig for IgA nephropathy
This trial tests a new drug called cizutamig for people with IgA nephropathy who still have high protein in their urine despite trying other treatments. It aims to see if the drug can help protect kidney function.
BeijingAges 18–75 - NCT07133659RecruitingPhase 4
New starting dose of avatrombopag for immune thrombocytopenia
This study tests a modified starting dose of avatrombopag, a medication that helps raise platelet counts, in adults with immune thrombocytopenia (ITP) who have not responded well to first-line steroid treatments. The goal is to see if this new dosing is effective and safe.
BaghdadAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,062 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,151 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.