Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,228 recruiting studies in this area right now.
By phase
- Not applicable3,145
- Phase 21,063
- Phase 1819
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis140
- Type 1 Diabetes133
- Atopic Dermatitis129
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California491
- Maryland195
- Alabama175
- Florida144
- Arizona142
- New York123
- Massachusetts119
- Texas118
- Illinois81
- Colorado77
Recruiting studies6,228 total
- NCT06064695Recruiting
Electrical muscle stimulation exercise for myasthenia gravis
This study tests if whole-body electrical muscle stimulation exercise can help adults with generalized myasthenia gravis. It also enrolls healthy controls for comparison. If you have MG and can stand for about 15 minutes, this may be an option.
Fairway, KansasAges 18 years+ - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06066203RecruitingPhase 1/Phase 2
Study of GNC-035 for lymphoma that returned or didn't respond to treatment
This trial tests a new drug, GNC-035, for people with non-Hodgkin's lymphoma that has come back (relapsed) or stopped responding to standard treatments (refractory). The goal is to see if GNC-035 can help when other options haven't worked.
Beijing, Beijing MunicipalityAges 18–75 - NCT06066346RecruitingPhase 2
Talquetamab for multiple myeloma after CAR T-cell therapy
This study tests a drug called talquetamab for people with multiple myeloma who have already had a type of immunotherapy called CAR T-cell therapy (ide-cel). The goal is to see if talquetamab can help control the cancer after the CAR T cells have had time to work.
Basking Ridge, New JerseyAges 18 years+ - NCT06068179RecruitingPhase 2/Phase 3
Can a new combo help Graves' disease go into remission?
This trial tests a combination of two medicines (methimazole and mycophenolate) to see if they can help people with newly diagnosed Graves' disease go into remission faster and more safely. If you are newly diagnosed and haven't had treatment yet, this study might offer a way to get better control of your condition.
Xiamen, FujianAges 18–60 - NCT06068114Recruiting
Stomach function study in people with diabetes
This study looks at how diabetes affects stomach function by measuring stomach activity with special tests. It may help doctors better understand and treat stomach problems in people with diabetes.
OstravaAges 18–70 - NCT06068335Recruiting
Understanding immunity in allergic asthma
This study looks at how the immune system works in people with allergies or asthma compared to healthy people. It may help find new ways to treat these conditions.
Orlando, FloridaAges 18 years+ - NCT06068582Recruiting
Keep your memory sharp and stay at work with MS
This study tests a program of physical and mental exercises designed to slow down memory and thinking problems in people with multiple sclerosis, and help them stay employed longer.
AmsterdamAges 18–67 - NCT06069492Recruiting
Wheat oral immunotherapy for children with wheat allergy
This trial tests whether a controlled, gradual treatment called oral immunotherapy can help children with wheat allergy eat wheat safely. It involves a supervised wheat challenge first, then daily wheat doses for 12 months.
Hong KongAges 1–17 - NCT06069583Recruiting
Support program for adults with type 1 diabetes
This trial tests an online support platform to help adults with type 1 diabetes manage their condition. If you live in Canada, have internet access, and can read English or French, you may be able to join.
Montreal, QuebecAges 18 years+ - NCT06072131RecruitingPhase 3
Comparing belinostat or pralatrexate with chemotherapy for PTCL
This trial tests whether adding belinostat or pralatrexate to standard chemotherapy (CHOP) works better than CHOP alone for people newly diagnosed with peripheral T-cell lymphoma (PTCL). It aims to find a more effective first treatment option.
Clovis, CaliforniaAges 18 years+ - NCT06072443Recruiting
Study to help people stick with their PrEP
This study tests ways to help people stick with their PrEP (the medicine that prevents HIV). If you're getting PrEP through West Virginia Health Right and have a smartphone, you may be able to join.
Charleston, West VirginiaAges 18 years+ - NCT06072703Recruiting
Brain stimulation for bladder control in MS
This study tests whether a type of brain stimulation can improve bladder control in women with multiple sclerosis. If you have bladder symptoms like urgency or frequent urination, this trial may help find new ways to manage them.
Houston, TexasAges 18 years+ - NCT06072768RecruitingPhase 2
Testing ways to safely lower steroid doses in rheumatoid arthritis
This study compares two different schedules for reducing prednisone (a steroid) in people with rheumatoid arthritis who are also taking another standard arthritis medicine. The goal is to find the safest and most effective way to taper off steroids without causing a flare-up.
Ann Arbor, MichiganAges 18 years+ - NCT06074354Recruiting
MY-RIDE app for HIV prevention and substance use in homeless youth
This study tests a smartphone app called MY-RIDE to help homeless youth prevent HIV and reduce substance use. The app sends helpful tips at the right time to support healthier choices.
Houston, TexasAges 18–25 - NCT06073938Recruiting
Compassionate Use of NHWD-870 for NUT-Positive Tumors
This trial offers early access to an experimental drug called NHWD-870 for people with advanced solid tumors or lymphomas that have a specific genetic change called a NUT rearrangement. The goal is to see if this drug can help shrink or slow the growth of these cancers.
Changsha, HunanAges 18–75 - NCT06074666Recruiting
Parent training to boost medication adherence in pediatric leukemia
This study tests a new parenting program to help improve how well children with leukemia take their oral medications at home. The program focuses on building helpful skills for giving daily medicine.
Buffalo, New YorkAges 3–9 - NCT06078098Recruiting
Autoimmune Hepatitis Database and Biobank Study
This study is building a database and collection of samples from people with autoimmune hepatitis in Italy. It aims to learn more about the disease and improve care.
Monza, MBAges 1 year+ - NCT06079294Recruiting
Autoimmune encephalitis and brain glucose metabolism
This study looks at how autoimmune encephalitis affects brain metabolism using a special PET scan. It aims to better understand the condition in people who were recently diagnosed.
ParisAges 18 years+ - NCT06080191RecruitingPhase 1
Donor CAR T cells for pediatric B-ALL relapse
This trial uses a one-time infusion of specially grown immune cells (CAR T cells) from a healthy donor to attack leukemia that has come back or not responded to prior treatments. It is for children and young adults with B-cell acute lymphoblastic leukemia that still shows the CD19 marker.
Rome, ItalyAges 1–35 - NCT06081231Recruiting
Open-source artificial pancreas study for type 1 diabetes in China
This study looks at how well an open-source artificial pancreas system (a do-it-yourself insulin pump and continuous glucose monitor that talk to each other) works for people with type 1 diabetes in China. You can join if you already use this system and are willing to share your data.
Guangzhou, GuangdongAges 3–75 - NCT06081439Recruiting
Immune markers and mental fatigue in Graves' disease
This study looks at whether certain immune system markers are linked to mental fatigue (feeling tired or foggy in the mind) in people with newly diagnosed Graves' disease. If you join, you'll help researchers understand how your immune system might affect your energy and thinking.
GothenburgAges 18–72 - NCT06081478RecruitingPhase 2
Targeted CAR-T cell therapy for advanced lymphoma or leukemia
This trial tests a new type of immune cell therapy (CAR-T) that targets two proteins on cancer cells—CD19 and CD22—to treat lymphoma or leukemia that has come back or not responded to standard treatment. It aims to see if this two-target approach works better.
Beijing, Beijing MunicipalityAges 14–85 - NCT06082102RecruitingPhase 3
Comparing orelabrutinib and lenalidomide with rituximab for MZL
This study tests two different drug combinations for people with marginal zone lymphoma that has come back or stopped responding to previous treatment. One group gets orelabrutinib plus rituximab, and the other gets lenalidomide plus rituximab, to see which works better and has fewer side effects.
Bengbu, AuhuiAges 18 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,228 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,761 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.