Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,068 recruiting studies in this area right now.
By phase
- Not applicable3,005
- Phase 21,062
- Phase 1794
- Phase 1/Phase 2441
- Phase 3435
- Phase 4233
- Phase 2/Phase 398
Top conditions
- Multiple Sclerosis330
- Multiple Myeloma328
- Asthma194
- Lymphoma179
- Rheumatoid Arthritis131
- Type 1 Diabetes131
- Atopic Dermatitis123
- Systemic Lupus Erythematosus121
- Acute Lymphoblastic Leukemia118
- HIV Infections106
- Chronic Lymphocytic Leukemia96
- Autoimmune Diseases79
- Follicular Lymphoma70
- Rheumatoid Arthritis (RA)68
- Hodgkin Lymphoma64
- Diabetes Mellitus, Type 163
- Leukemia63
- Type 1 Diabetes Mellitus63
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)97
- Institute of Hematology & Blood Diseases Hospital, China85
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris65
- AstraZeneca64
- M.D. Anderson Cancer Center58
- Novartis Pharmaceuticals58
- Mayo Clinic50
- City of Hope Medical Center49
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California498
- Maryland198
- Alabama179
- Florida152
- Arizona150
- Massachusetts118
- New York116
- Texas112
- Illinois82
- Colorado81
Recruiting studies6,068 total
- NCT06923202Recruiting
Studying alloknesia in atopic dermatitis
This study looks at a condition called alloknesia (a feeling that a light touch is painful) in people with atopic dermatitis (a type of eczema). It aims to understand how common this is and what it feels like.
AngersAges 18 years+ - NCT06930976Recruiting
Tracing sugar use in immune cells
This study uses a special sugar (glucose) to see how your immune cells use energy. You drink a labeled sugar, then give blood samples so researchers can track it.
Nashville, TennesseeAges 18 years+ - NCT06927466RecruitingPhase 1
B019 for relapsed or refractory B-cell acute lymphoblastic leukemia
This trial tests a new treatment called B019 for people whose B-cell acute lymphoblastic leukemia has come back or not responded to standard therapy. The treatment targets specific proteins on the cancer cells to help your immune system fight the leukemia.
BeijingAges 3–25 - NCT06929299RecruitingPhase 1/Phase 2
Testing STSA-1301 for immune thrombocytopenia (ITP)
This trial tests a new drug called STSA-1301 for people with immune thrombocytopenia (ITP), a condition where the immune system attacks platelets. The study has two parts: one for healthy volunteers to check safety, and one for ITP patients to see if the drug can raise platelet counts and reduce bleeding risk.
Bengbu, AnhuiAges 18–75 - NCT06927999RecruitingPhase 2
Experimental medicine for chronic hives
This trial tests an experimental medicine for chronic hives (called chronic spontaneous urticaria). It is for people whose hives still bother them about once or twice a month despite daily treatment, and who do not have heart problems.
Glenview, IllinoisAges 18–65 - NCT06742671Recruiting
Fast-track pathway for giant cell arteritis diagnosis
This trial tests a fast-track process to quickly diagnose giant cell arteritis (GCA), a condition that causes blood vessel inflammation. It may help patients get the right care faster.
La RochelleAges 50 years+ - NCT04183101RecruitingPhase 2
Aliskiren vs enalapril for C3 kidney inflammation
This trial tests whether aliskiren works better or as well as enalapril to treat C3 glomerulopathy/dense deposit disease confirmed by a kidney biopsy. It may help by improving kidney outcomes in people with this specific kidney condition.
GothenburgAges 6 years+ - NCT05780099Recruiting
Study of patients treated in internal medicine clinics
This observational study follows people receiving care in Internal Medicine at San Raffaele Hospital to better understand what kinds of conditions they have. It does not test a new treatment, but your information may help improve future care.
MilanAges 18 years+ - NCT06918002RecruitingPhase 3
Comparing elranatamab with standard care for newly diagnosed multiple myeloma
This trial tests if adding the immunotherapy drug elranatamab (with or without lenalidomide) after initial treatment works better than the usual care for people with newly diagnosed multiple myeloma who are eligible for a stem cell transplant.
BrusselsAges 18–69 - NCT06919003RecruitingPhase 2
Improving kidney transplant with a single injection of a protective protein
This trial tests whether a single injection of C1 esterase inhibitor into a donated kidney during preservation can improve transplant outcomes. It is for adults on dialysis waiting for a deceased-donor kidney who meet specific blood and tissue matching requirements.
Los Angeles, CaliforniaAges 18–75 - NCT06918990RecruitingPhase 1
CarBel for antibody-mediated rejection after kidney transplant
This study tests a new drug called CarBel to treat antibody-mediated rejection in kidney transplant patients. The goal is to see if it can help stop the rejection and protect your new kidney.
Birmingham, AlabamaAges 18–75 - NCT06860750RecruitingPhase 3
SHR-1314 injection for active non-radiographic axial spondyloarthritis
This trial tests a new injection called SHR-1314 for people with active non-radiographic axial spondyloarthritis (a type of inflammatory arthritis that doesn't show on X-rays but causes back pain and stiffness). It may help reduce inflammation and improve symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06917742RecruitingPhase 1
Study of CPTX2309 for rheumatoid arthritis and lupus
This trial tests an investigational drug called CPTX2309, given intravenously, for people with moderate to severe rheumatoid arthritis or systemic lupus erythematosus. It aims to see if the drug is safe and effective.
Herston, QueenslandAges 18–65 - NCT06915246RecruitingPhase 2
Carmustine with or without ethanol for lymphoma transplant
This trial tests a chemotherapy drug called carmustine, with or without ethanol (alcohol), to see if it works better for people with lymphoma who are getting a stem cell transplant. You may be eligible if you have Hodgkin or Non-Hodgkin lymphoma, have responded well to treatment, and are healthy enough for a transplant.
Goodyear, ArizonaAges 18 years+ - NCT06918808RecruitingPhase 2
Stem cell therapy for Crohn's fistula healing
This trial tests if a special stem cell treatment (called DB-3Q bmMSC-EVs) can help heal fistulas caused by Crohn's disease. It's for people who have already tried other treatments and still have actively draining fistulas.
Aurora, ColoradoAges 18–75 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Duarte, CaliforniaAges 18–55 - NCT06920199RecruitingEarly Phase 1
Donor Treg cells plus IL-2 for stubborn chronic GVHD
This trial tests whether injecting special immune cells (Treg cells) from your transplant donor, along with a protein called IL-2, can help control chronic graft-versus-host disease (cGVHD) that hasn't responded well to steroids. It is for people who have had a stem cell transplant and still have moderate to severe cGVHD.
ShanghaiAges 18–70 - NCT06915831Recruiting
Type 1 diabetes and sleep apnea study
This study looks at how sleep apnea affects blood sugar control in adults with type 1 diabetes. It may help researchers understand if treating sleep apnea improves diabetes management.
Chicago, IllinoisAges 18–50 - NCT06921239Recruiting
HLA antibodies in lupus patients
This study looks for certain immune markers (HLA antibodies) in stored blood samples from people with lupus. It may help doctors understand how the immune system behaves in lupus.
AmiensAges 18 years+ - NCT06916104Enrolling by invitation
Allergies and biotherapy in severe asthma
This study looks at whether having a respiratory allergy affects how well biotherapy works for people with severe asthma. It includes adults already on biotherapy and followed at Poitiers University Hospital.
PoitiersAges 18 years+ - NCT06921980Recruiting
Cell therapy and brain function in AIHA
This trial looks at how cell therapy may affect your brain function and mood if you have autoimmune hemolytic anemia. It aims to help doctors understand the psychological changes that can happen during treatment.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT06919900Recruiting
Learning fall-resistant skills in multiple sclerosis
This trial tests if practicing slips and trips can help people with multiple sclerosis learn to prevent falls. You will be exposed to controlled slips and trips to improve your balance and walking safety.
Atlanta, GeorgiaAges 45–89 - NCT06920251RecruitingPhase 2
Preventing CMV Infection During Elranatamab Treatment for Myeloma
This trial tests whether giving letermovir (a medication to prevent CMV infection) is safe and effective for people with relapsed/refractory multiple myeloma who are starting elranatamab therapy. It is for patients who have already had several prior treatments and have been exposed to CMV in the past.
SeoulAges 19 years+
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,068 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,217 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.