Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,230 recruiting studies in this area right now.
By phase
- Not applicable3,146
- Phase 21,063
- Phase 1820
- Phase 1/Phase 2442
- Phase 3425
- Phase 4238
- Phase 2/Phase 396
Top conditions
- Multiple Sclerosis343
- Multiple Myeloma332
- Asthma194
- Lymphoma183
- Rheumatoid Arthritis140
- Type 1 Diabetes134
- Atopic Dermatitis130
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia122
- HIV Infections113
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Rheumatoid Arthritis (RA)66
- Leukemia64
- Type 1 Diabetes Mellitus63
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)73
- Assistance Publique - Hôpitaux de Paris70
- M.D. Anderson Cancer Center63
- Novartis Pharmaceuticals60
- AstraZeneca57
- City of Hope Medical Center47
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center44
Where studies are running
- California494
- Maryland195
- Alabama176
- Florida145
- Arizona141
- New York122
- Massachusetts119
- Texas118
- Illinois81
- Colorado76
Recruiting studies6,230 total
- NCT06985576Enrolling by invitation
Long-term safety follow-up for GF-CART01
This study is a long-term follow-up for people who have already received the GF-CART01 treatment in a previous study. It checks how safe the treatment stays over time and how long the effects last.
TaipeiAges Any age - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06971445Enrolling by invitation
Omega-3 supplements for pregnant women with HIV
This trial tests whether taking omega-3 supplements can improve pregnancy outcomes and reduce inflammation in pregnant women living with HIV who are on antiretroviral therapy. If you are between 20 and 29 weeks pregnant with a single baby, you may be eligible to join.
Mexico City, Mexico CityAges 18 years+ - NCT06957444Enrolling by invitation
Allergic skin reactions and scar appearance after joint replacement
This study looks at how often patients have an allergic skin reaction to the stitches used after knee or hip replacement, and how their scar looks. If you are having a first-time replacement, you may be able to join.
Morgantown, West VirginiaAges 18–80 - NCT06955962Enrolling by invitation
Mandala art therapy for multiple sclerosis symptoms and quality of life
This trial tests whether creating mandala art can help improve symptoms and quality of life for people with multiple sclerosis. You would participate in art sessions while continuing your regular MS care.
TrabzonAges 18–65 - NCT06947252Enrolling by invitation
Food allergy test for kids with eczema avoiding certain foods
This trial tests if children with eczema who avoid certain foods actually have a food allergy. It uses a supervised oral food challenge to confirm.
BangkokAges Up to 6 years - NCT06940869Enrolling by invitation
Reproductive health registry for rheumatic conditions
This study creates a registry to better understand pregnancy outcomes in people with autoimmune or rheumatic conditions. If you are aged 12 to 55, can become pregnant (or are currently pregnant or planning a pregnancy), and receive care at Duke Health, you may be eligible to join.
Durham, North CarolinaAges 12–55 - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06931613Enrolling by invitationPhase 2
STEM CELL TRANSPLANT FOR HODGKIN LYMPHOMA AFTER NIVOLUMAB
This trial tests a stem cell transplant using your own cells for children and teens with Hodgkin lymphoma that has come back or not gotten better after multiple treatments. It involves using a medicine called nivolumab before the transplant to help your body fight the cancer.
MoscowAges 2–18 - NCT06916104Enrolling by invitation
Allergies and biotherapy in severe asthma
This study looks at whether having a respiratory allergy affects how well biotherapy works for people with severe asthma. It includes adults already on biotherapy and followed at Poitiers University Hospital.
PoitiersAges 18 years+ - NCT06908083Enrolling by invitationPhase 1
Stopping HIV treatment with antibody therapy
This trial tests whether a combination of powerful antibodies (bNAbs) can help control HIV after stopping standard HIV treatment. Participants will pause their daily HIV medications while receiving these antibodies, and doctors will closely monitor their immune system and virus levels. It's for people who are already well-controlled on HIV treatment and have participated in a specific earlier study.
Bethesda, MarylandAges 18–70 - NCT06900244Enrolling by invitation
Metabolic Imaging for MS and Stroke
This study uses a special type of MRI scan to look at how energy is used in the brain. It may help researchers better understand neurological diseases like multiple sclerosis (MS) and stroke.
OxfordAges Up to 99 years - NCT06888973Enrolling by invitationPhase 1/Phase 2
Stem cell infusion for autoimmune diseases
This clinical trial is testing if infusions of special stem cells (called mesenchymal stem cells) can help people with certain autoimmune diseases where standard treatments have not worked well enough. It is an early-phase study in Pakistan for adults (and some children for one condition) with rheumatoid arthritis, lupus, systemic sclerosis, ankylosing spondylitis, or dermatomyositis/polymyositis.
RawalpindiAges 18–50 - NCT06881654Enrolling by invitation
Teeth whitening with a softer tray vs. a rigid tray
This trial compares two types of trays used for at-home teeth whitening with a 16% carbamide peroxide gel: a soft tray versus a rigid tray. The goal is to see if one works better and feels more comfortable.
Alcorcón, MadridAges 18 years+ - NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06877403Enrolling by invitation
Fatigue study in myasthenia gravis patients
This study looks at how common and how severe fatigue is in people with myasthenia gravis. It aims to understand the impact of fatigue on daily life and may help improve care for patients with this condition.
Clermont-FerrandAges 18 years+ - NCT06874764Enrolling by invitation
Training with a wireless system for thinking and reaction in MS
This study tests whether a special wireless reaction training system can help improve thinking and reaction speed in people with multiple sclerosis (MS). It compares this training to standard exercises to see which works better for your brain health.
Izmir, BornovaAges 18–55 - NCT06873464Enrolling by invitation
Brain stimulation to reduce fatigue in multiple sclerosis
This trial tests if a gentle brain stimulation technique (tDCS) can help reduce fatigue and improve quality of life for people with multiple sclerosis. You would receive either real or placebo stimulation over several sessions to see if it helps you feel less tired.
MadridAges 18–75 - NCT06864598Enrolling by invitation
New immune cells to help stem cell transplant success
This trial tests whether a special type of immune cell (called CD8 regulatory precursors) can help prevent the body from rejecting a stem cell transplant from a donor. It is for patients receiving a stem cell transplant from a related donor.
Beijing, Beijing MunicipalityAges 18–60 - NCT06851403Enrolling by invitation
Dupilumab for children with asthma in China
This study looks at how well and how safely the medicine Dupilumab works for children whose asthma is not well-controlled with their current inhalers. The goal is to see if it can help reduce asthma attacks and improve daily life.
Guangzhou, GuangdongAges 4–16 - NCT06849960Enrolling by invitation
Reliability and validity of the Two-minute Test for Multiple Sclerosis
This study tests whether a simple two-minute walking test is a reliable way to measure function in people with multiple sclerosis. It aims to help doctors and patients understand the true value of this quick, easy test.
Şehitkamil, GaziantepAges 18–65 - NCT06848738Enrolling by invitation
Faster biopsy for lung cancer or lymphoma near the esophagus
This trial tests a faster way to get a tissue sample from lung cancer or lymphoma tumors that are near the esophagus or stomach. The goal is to start your treatment sooner by using a special ultrasound scope to do a biopsy right away.
NæstvedAges 18 years+ - NCT06831331Enrolling by invitation
Diet and nutrition for newly diagnosed rheumatoid arthritis
This study tests whether a special diet can help manage symptoms of newly diagnosed rheumatoid arthritis. It aims to see if eating certain foods can reduce inflammation and improve your overall health.
GothenburgAges 18–85 - NCT06827782Enrolling by invitationPhase 1
Cord blood CAR-NK cells for relapsed CNS lymphoma
This trial tests a new treatment using specially engineered immune cells from cord blood to target and kill cancer cells in the brain or spine. It is for people whose central nervous system lymphoma has not responded to or has returned after previous treatments.
Hangzhou, ZhejiangAges 18–75
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,230 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,786 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.