Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,175 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2362
- Phase 4321
- Phase 1291
- Phase 3285
- Phase 1/Phase 2142
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona47
- Pennsylvania45
- Illinois42
Recruiting studies4,175 total
- NCT07779720Recruiting
Personalized fluids for emergency sepsis care
This trial tests a personalized approach to giving IV fluids to patients with sepsis in the emergency department. It uses a device to monitor your heart and blood flow to help doctors decide how much fluid you need, which may improve recovery.
Murray, UtahAges 18 years+ - NCT07698600RecruitingPhase 1
Safety test of a new HIV vaccine in adults with or without HIV
This study tests a new RNA-based vaccine called BNT168 to see if it is safe and how the body responds to it. It is for healthy adults with or without HIV, and those with HIV will pause their regular treatment for a while during the study.
Houston, TexasAges 18–50 - NCT07240077RecruitingPhase 4
Adding levofloxacin to beta-lactam for streptococcal blood infection
This trial tests whether adding levofloxacin to standard beta-lactam antibiotics works better for treating streptococcal blood infections. It may help if you have a confirmed strep infection in your blood and are already on or about to start beta-lactam therapy.
BangkokAges 18 years+ - NCT06317662RecruitingPhase 2
Adding venetoclax and blinatumomab to chemo for infant leukemia
This trial tests adding two newer medicines (venetoclax and blinatumomab) to standard chemotherapy for infants with a specific type of leukemia. The goal is to see if this combination helps more babies stay cancer-free.
Birmingham, AlabamaAges Up to 12 months - NCT02140255RecruitingPhase 1/Phase 2
Intensive early HIV treatment in newborns to aim for remission
This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.
La Jolla, CaliforniaAges Up to 2 days - NCT07532941RecruitingPhase 4
Stopping antibiotics early versus completing the full course
This study compares two ways of giving antibiotics to children: stopping when symptoms feel better versus finishing all the prescribed doses. Researchers want to see if stopping early is safe and works just as well, which could help reduce unnecessary antibiotic use.
Melbourne, VictoriaAges 1–17 - NCT07226128Recruiting
Can therapy help HIV patients with depression and insulin resistance?
This study tests if cognitive behavioral therapy (a type of talk therapy) can improve how your body handles sugar (insulin resistance) for people living with HIV who also have depression. You may join if you have HIV, are on stable HIV meds, feel depressed, and do not have diabetes.
Indianapolis, IndianaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT07432113Recruiting
Predicting meningitis and encephalitis causes from spinal fluid
This trial tests a method to quickly identify the cause of meningitis or encephalitis by looking at your symptoms and spinal fluid results. It may help doctors choose the right treatment faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06887036RecruitingPhase 2
Methylene blue for chronic inactive hepatitis B
This trial tests whether a medication called methylene blue can help lower the amount of hepatitis B virus in people with a chronic but inactive infection. It may be an option for people whose virus levels are stable but not fully controlled.
Lugano, Canton TicinoAges 18–79 - NCT06538961Recruiting
Immune registry for BK virus in kidney transplant patients
This study is creating a registry to learn how the immune system responds to BK virus in people who have recently received a kidney transplant from a deceased donor. Researchers hope this information will help improve treatment for BK virus infections.
Richmond, VirginiaAges 18 years+ - NCT07170917RecruitingPhase 2
Testing a new drug for moderate to severe hidradenitis suppurativa
This trial tests a new drug called Brivekimig for people with moderate to severe hidradenitis suppurativa (HS) who have not gotten enough relief from oral antibiotics. The goal is to see if it can reduce abscesses and inflamed bumps.
Phoenix, ArizonaAges 18 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT07306026Recruiting
Testing a toothbrush's bristles on plaque and gums
This trial compares how well different toothbrush bristles remove plaque and affect gum health. It may help find the best toothbrush design for everyday oral care.
Buffalo, New YorkAges 18–70 - NCT07508839Recruiting
Probiotic lozenge study for healthy adults
This trial tests a probiotic lozenge (a dissolvable tablet) to see if it's safe and works well. It's for healthy adults who don't smoke and are between 18 and 70 years old.
Hamilton, OntarioAges 18–70 - NCT07774962Recruiting
Comparing fingertip refill time and blood oxygen use in septic shock
This study looks at two ways to check blood flow and oxygen use in people with septic shock, a severe infection-related condition. It aims to see if a simple bedside test (fingertip refill) and a blood measure (oxygen extraction ratio) agree, which could help guide treatment.
IstanbulAges 18 years+ - NCT07772791Recruiting
Online study on digital tools for HIV prevention and treatment in Brazil
This study tests online programs to help people who are at higher risk for HIV get prevention or treatment. It aims to see if digital tools can improve access to and use of HIV medications.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06137118RecruitingPhase 1/Phase 2
Study of AZD0486 for relapsed or refractory B-cell ALL
This trial tests a new investigational drug (AZD0486) given alone to see if it is safe and effective for people with B-cell acute lymphoblastic leukemia (ALL) that has come back or hasn't responded to treatment. It specifically targets a protein called CD19 found on leukemia cells.
Birmingham, AlabamaAges 12 years+ - NCT04567771Recruiting
Proton vs IMRT radiation after surgery for uterine or cervical cancer
This study compares two types of radiation therapy (proton and IMRT) given after surgery for endometrial or cervical cancer. It aims to see which treatment is better at reducing side effects while still being effective.
Scottsdale, ArizonaAges 18 years+ - NCT05082519RecruitingPhase 2
Calorie restriction and exercise to improve leukemia treatment in young patients
This study tests whether a special diet (calorie restriction) and increased physical activity can make chemotherapy work better for young people with B-ALL. Participants will follow a monitored diet and exercise plan during their first month of treatment.
Los Angeles, CaliforniaAges 7–25 - NCT07249463RecruitingPhase 2
Testing a new drug for cryptosporidium infection in healthy adults
This trial tests a new drug, EDI048, to see how well it works and how safe it is for treating cryptosporidium infection. It is for healthy volunteers who will be intentionally exposed to the infection under controlled conditions.
Baltimore, MarylandAges 18–50 - NCT06632600RecruitingPhase 2
Study of LXE408 for people with chronic Chagas disease
This trial tests a new drug called LXE408 for people with chronic Chagas disease. It aims to see if the drug is safe and effective, and participants will also receive standard treatment with benznidazole.
Sylmar, CaliforniaAges 18–60 - NCT07290439Recruiting
Fast STI testing for pregnant women
This study tests a quick way to check for STIs during pregnancy or labor at Grady Memorial Hospital. It aims to improve health for mothers and babies by finding infections early.
Atlanta, GeorgiaAges Any age - NCT07214311RecruitingPhase 2/Phase 3
A trial of PLG0206 to prevent knee joint infection after surgery
This trial tests if a new drug called PLG0206 can stop a knee joint infection from coming back after a surgery called DAIR. DAIR cleans the infected area and keeps the artificial knee in place, and this study wants to see if adding PLG0206 helps prevent the infection from returning.
Sarasota, FloridaAges 18–80
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,175 recruiting infectious disease studies from the U.S. registry right now, out of 7,037 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.