Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,391 recruiting studies in this area right now.
By phase
- Not applicable2,721
- Phase 2568
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 355
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong35
- Novartis Pharmaceuticals33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California358
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,391 total
- NCT04106115RecruitingPhase 1/Phase 2
Durvalumab vaccine trial for high-risk bladder cancer after BCG
This early-phase trial tests durvalumab given with an experimental bladder cancer vaccine to help stop or slow high-risk bladder cancer that did not respond to or cannot be treated with BCG. It also evaluates safety and how well the treatment works in this setting.
CambridgeAges 18 years+ - NCT04038619RecruitingPhase 1
Fecal transplant for immune-therapy diarrhea or bowel inflammation
This early-phase study tests whether stool/fecal microbiota transplant (a fecal transplant) can help people who develop significant diarrhea or colitis after immune-checkpoint therapy. It aims to reduce bowel inflammation and improve symptoms, while carefully checking for infections.
Houston, TexasAges 18 years+ - NCT04133675Recruiting
Emsella chair test for stress urine leakage
This study compares the Emsella chair treatment to a fake (sham) treatment to see which works better for stress urinary incontinence—leaking urine with coughing, laughing, or exertion. If you qualify, you may get the real chair, and you will complete questionnaires and follow specific rules about other treatments.
Royal Oak, MichiganAges 18–80 - NCT04095156Recruiting
Study of immune B cells in membranous nephropathy
This study looks at immune “B cells” in people with membranous nephropathy (a kidney disease). It includes people who have received or are being considered for B-cell–depleting treatment, aiming to better understand what drives the disease and how it may respond.
Ranica, BGAges 18 years+ - NCT03949855RecruitingPhase 2
Belimumab plus rituximab for primary membranous nephropathy
This study tests whether adding belimumab to rituximab helps people with primary membranous nephropathy (a kidney disease) that has the right blood test marker and specific protein levels. The goal is to improve kidney outcomes and reduce disease activity while keeping treatment safe.
Birmingham, AlabamaAges 18–75 - NCT03972657RecruitingPhase 1/Phase 2
Testing a new prostate and kidney cancer drug with immunotherapy
This early trial tests whether REGN5678 (nezastomig) is safe and how well it works, either by itself or with an immunotherapy drug (cemiplimab). It targets adults with metastatic castration-resistant prostate cancer and certain metastatic kidney cancers that have already been treated.
Gilbert, ArizonaAges 18 years+ - NCT03994471RecruitingPhase 3
Testing a new peritoneal dialysis fluid for kidney failure
This Phase 3 trial studies how well a new peritoneal dialysis solution works and whether it is safe. It’s meant for adults with kidney failure who already do a specific type of at-home dialysis.
AalborgAges 18 years+ - NCT03969329RecruitingPhase 3
Etelcalcetide for children on dialysis with high parathyroid hormone
This Phase 3 trial tests etelcalcetide to lower a hormone called parathyroid hormone (PTH) in children who have kidney disease and secondary hyperparathyroidism while on hemodialysis. It may help control bone/mineral problems, but the study also checks heart rhythm safety and medication stability.
GhentAges 2–17 - NCT03955445RecruitingPhase 3
Study for long-term iptacopan in C3G or IC-MPGN
This Phase 3 trial looks at how well and how safely iptacopan works over the long term for people with C3G or IC-MPGN. You may be able to join if you already finished a specific earlier study and you’re currently healthy enough for long-term treatment.
Aurora, ColoradoAges 12–100 - NCT03880422Recruiting
Exercise and nutrition for weight and frailty after prostate cancer treatment
This study tests whether a structured exercise and nutrition program can improve obesity-related frailty and overall function in people with advanced prostate cancer who are taking hormone therapy (ADT). It may help with strength, mobility, and healthier body weight during/after ADT.
Buffalo, New YorkAges 18 years+ - NCT03979534Recruiting
Protecting Kidneys With a Low-Protein Diet
This study tests whether a step-by-step low-protein diet can help protect your kidneys if you have advanced chronic kidney disease (stages 4 or 5) or stage 3 that is getting worse quickly. The goal is to see if this diet approach can slow down kidney damage.
La FlècheAges 18 years+ - NCT03952299RecruitingPhase 3
Oxybutynin patch after bladder surgery for children’s urgency pain
This study tests whether an oxybutynin skin patch after bladder surgery can reduce bladder pain and urgent, frequent urination in children. It compares symptoms after surgery to see if the patch helps more than the control plan.
Sacramento, CaliforniaAges 4–8 - NCT03954678Recruiting
Exercise program during hospital care for urologic surgery
This study looks at whether doing an exercise routine around the time of urologic (urinary tract) surgery is safe and helpful for recovery. It asks you to do daily steps, answer questionnaires, and allow routine bloodwork.
Atlanta, GeorgiaAges 18 years+ - NCT03901521Enrolling by invitation
Biobank for people with autosomal dominant polycystic kidney disease
This study collects samples and health information from adults with autosomal dominant polycystic kidney disease (ADPKD) who are having their own kidney removed. It helps researchers learn more about ADPKD and its genetic changes to support future treatments.
New York, New YorkAges 18–100 - NCT03943238RecruitingPhase 1
Kidney transplant with immune therapy to prevent rejection
This trial tests a combination of low-dose radiation, chemotherapy, and donor immune cells to help your body accept a living donor kidney without long-term anti-rejection drugs.
Palo Alto, CaliforniaAges 18–65 - NCT03933670RecruitingPhase 2
MRI scan with special sugar to monitor prostate cancer on surveillance
This study uses a special MRI scan using “hyperpolarized” labeled pyruvate (a sugar-like substance) to see how prostate cancer may be behaving in people who are on active surveillance. It may help researchers monitor cancer without immediate treatment, by spotting changes earlier.
San Francisco, CaliforniaAges 18 years+ - NCT03981497Recruiting
Microwave treatment for small, hard-to-remove liver and kidney tumors
This trial tests using a “microwave ablation” procedure to destroy small liver or kidney tumors when surgery isn’t an option or can’t remove everything. It may help patients avoid major surgery by targeting tumors directly with heat.
MilanAges 18 years+ - NCT03977571Recruiting
Surgery plus cancer drugs for kidney cancer that spread
This trial studies whether removing the kidney tumor with “deferred cytoreductive nephrectomy” (surgery at a later time) works best for people whose metastatic kidney cancer is already present. It compares a standard treatment approach using either immunotherapy (nivolumab/ipilimumab) or a targeted pill plus immunotherapy (TKI/IO), with planned surgery afterward.
Aarhus, Central Region of DenmarkAges 18 years+ - NCT03866382RecruitingPhase 2
Immunotherapy plus a targeted drug for rare genitourinary tumors
This Phase 2 study tests whether nivolumab and ipilimumab (immunotherapy drugs) plus cabozantinib (a targeted anti-cancer drug) can shrink or control rare cancers of the urinary/reproductive system that have spread. It may help by boosting the immune system and blocking cancer growth signals at the same time.
Birmingham, AlabamaAges 18 years+ - NCT03805919Recruiting
Study for men with high inherited risk of prostate cancer
This study is for men who have a known inherited gene change that raises their prostate cancer risk. It aims to help prevent or detect prostate cancer earlier, and you may be asked to undergo MRI and other study steps.
Bethesda, MarylandAges 30–75 - NCT03836482Recruiting
SCD test for people with heart and kidney failure awaiting LVAD
This study looks at whether a treatment called SCD is safe and workable in people who have worsening heart failure along with kidney problems, and who are waiting to get an LVAD (a mechanical heart pump). It is mainly a feasibility study, meaning the researchers want to see if this approach can be used in real hospital care and monitor effects on key health measures.
Ann Arbor, MichiganAges 18 years+ - NCT03767595Recruiting
Study of ProACT implant for long-term urine leak control
This study follows men who have urine leakage from stress (leakage with movement/coughing) after prostate surgery and receive a ProACT device. It looks at long-term outcomes over 5 years and checks safety, including for those who may need device removal or other treatments.
Los Angeles, CaliforniaAges 50 years+ - NCT03873259Recruiting
Testing a new way to check kidney stones during surgery
This trial tests a method called burst wave lithotripsy (BWL) to help doctors assess and treat kidney stones during a planned ureteroscopy procedure. It may help surgeons confirm how well the stone is being broken while you are on the operating table.
Carmel, IndianaAges 18 years+ - NCT03784924Recruiting
Prostate MRI study to find blood and urine cancer signals
This study enrolls men who may have prostate cancer but do not yet have a diagnosis. It uses prostate MRI along with blood and urine tests to see if specific signals can help identify prostate cancer sooner.
Ann Arbor, MichiganAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,391 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,874 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.