Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,505 recruiting studies in this area right now.
By phase
- Not applicable2,822
- Phase 2562
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4195
- Phase 2/Phase 359
Top conditions
- Prostate Cancer651
- Bladder Cancer192
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer105
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer56
- Lupus Nephritis53
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Head and Neck Cancer46
- Prostate Cancer (Adenocarcinoma)46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong34
- Novartis Pharmaceuticals34
- AstraZeneca29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama111
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,505 total
- NCT05334979Recruiting
Study oxalate and citrate in people with and without kidney stones
This study compares urine levels of oxalate and citrate in adults who have had calcium kidney stones and adults who have never had stones. It may help researchers understand how these urine chemicals relate to stone risk.
Chicago, IllinoisAges 18–70 - NCT05337189Recruiting
Urine DNA test study for possible bladder cancer
This trial looks at how a urine DNA test may help find bladder cancer (or clues that it might be present), especially in people with symptoms or higher risk. You may be asked to provide urine and also complete standard tests like imaging, a cystoscopy, or pathology checks.
Beijing, Beijing MunicipalityAges Any age - NCT05337397Recruiting
Outpatient laser treatment for repeat low-grade bladder tumors
This trial tests an outpatient laser procedure to remove recurring low-grade, non-solid bladder tumors. It may help prevent or control tumor growth with treatment done outside the hospital, if you meet the tumor and health criteria.
AarhusAges 18 years+ - NCT05339139RecruitingPhase 3
Testing citrate blood-thinning during kidney dialysis in adults
This study tests how safe a specific blood thinner called “citrate” is when used during continuous kidney dialysis (CRRT) for people with AKI or kidney failure. If you qualify, your care team will compare citrate safety against standard approaches to see if it’s tolerable and safe.
Little Rock, ArkansasAges 18 years+ - NCT05344235Recruiting
Study of very short radiation schedules for prostate cancer
This observational study looks at how well men with localized prostate cancer do when treated with an unusually short radiation approach. It may help doctors understand which patients benefit most by tracking outcomes and imaging over time.
Leuven, Vlaams BrabantAges Any age - NCT05344573Recruiting
Testing better blood-flow rhythms during heart bypass surgery
This trial studies ways to control the “pulsatility” (how the blood pressure pulses during circulation) while you are on a heart-lung bypass machine. It may help improve safety and heart function during planned heart surgery.
Aurora, ColoradoAges 50–70 - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT05346848RecruitingPhase 2
Darolutamide plus radiation for intermediate-risk prostate cancer
This trial tests whether adding darolutamide to standard radiation can better control intermediate-risk prostate cancer. It includes men whose cancer has spread nowhere else and who are newly diagnosed with “unfavorable intermediate risk” or progress to that risk group.
AvignonAges 18 years+ - NCT05349227Recruiting
After-cancer digital coaching and wearable tracking outcomes study
This study tests a digital health coaching program (using phone/tablet check-ins and wearable data) to understand health and quality-of-life outcomes after cancer treatment. It may help you learn healthy habits and track progress over time.
Gainesville, FloridaAges 18 years+ - NCT05348876RecruitingPhase 4
Darolutamide plus standard hormone therapy for high-risk prostate cancer
This trial studies how safe darolutamide is and how well it works when added to standard hormone therapy for men with high-risk, non-metastatic prostate cancer that is no longer responding to hormone treatment. It may help slow prostate cancer growth and reduce prostate-specific antigen (PSA) rises in real-world care.
Vijayawada, Andhra PradeshAges 18 years+ - NCT05349292Recruiting
Check hemodilution’s effect on urine kidney stress markers
This study tests a technique used during planned heart bypass surgery to see whether it changes substances measured in urine that reflect kidney stress or injury. If you have upcoming elective bypass surgery, your team may collect blood and urine samples to study how your kidneys respond.
Baltimore, MarylandAges 18–70 - NCT05349955Recruiting
Primary care diabetes guideline program for older adults
This trial tests whether a diabetes treatment plan (based on published guidelines) delivered by primary care doctors in the community is safe and helpful for older adults. It focuses on people with type 2 diabetes who also have kidney problems and/or higher heart and blood-vessel risk.
Suzhou, JaingsuAges 65 years+ - NCT05351424Recruiting
Spanish-language cancer care support for breast or prostate radiation
This study tests an educational and communication support program to help Spanish-speaking people stay on track with treatment when they’re getting radiation for non-spread (non-metastatic) breast or prostate cancer. It may help by improving understanding through interpreter-supported visits.
Miami Beach, FloridaAges 18 years+ - NCT05352178RecruitingPhase 3
Targeted treatment for few-spread prostate cancer spots
This Phase 3 trial tests whether treating only a small number of prostate cancer metastases can help people with “oligorecurrent” (limited repeat) prostate cancer. It may reduce cancer activity while avoiding broader whole-body treatment for some patients.
LeuvenAges 18 years+ - NCT05353946Recruiting
Rotational atherectomy elective vs emergency for heavily calcified blockages
This trial compares doing a special procedure (rotational atherectomy) before an emergency is needed versus using it as a rescue during a heart artery procedure. It is designed for people with very hard, calcified artery blockages and long-term kidney impairment, to see which approach works better and is safer.
MadridAges 18–100 - NCT05353660Recruiting
Study diet and muscle loss in people with kidney disease
This trial is for adults with chronic kidney disease and low muscle strength (sarcopenia). It aims to find ways to improve outcomes, especially if you have a higher risk of complications.
Guangzhou, GuangdongAges 18–80 - NCT05356000Recruiting
Testing how oxalate is absorbed to help prevent kidney stones
This study looks at how your body absorbs oxalate, a natural chemical that can contribute to calcium kidney stones. If you’ve had calcium stones—especially with high urine oxalate—it may help researchers find ways to reduce future stone risk.
Chicago, IllinoisAges 18–70 - NCT05359263RecruitingPhase 2
Dapagliflozin for kidney disease to improve heart structure
This Phase 2 study tests whether dapagliflozin can improve heart structure and function in people with chronic kidney disease (CKD). Dapagliflozin is a kidney-heart medicine that may affect how the heart changes over time, measured by heart scans.
CopenhagenAges 18 years+ - NCT05360914Recruiting
Hospital care at home for older adults with acute illnesses
This trial tests whether it is safe and helpful to manage certain sudden (acute) infections and medical problems with hospital-level care delivered at home or in a nursing home. It may help you avoid unnecessary hospital stays while still getting close medical follow-up.
SilkeborgAges 65 years+ - NCT05362292RecruitingPhase 4
Treating bladder leakage to support mind and body health
This study tests medicines to reduce “urgency” urine leakage (when you suddenly feel you must go) and to see whether improving bladder control also helps overall mental and physical health. You may be eligible if you have had these symptoms for at least 3 months and can follow the study plan.
Palo Alto, CaliforniaAges 60 years+ - NCT05363280RecruitingPhase 2
Second-treatment study for lung or kidney cancer after initial therapy
This Phase 2 study tests a new treatment for people with small cell lung cancer, non-small cell lung cancer, or kidney cancer after they have finished their first main treatment. It may help shrink tumors or control the cancer further.
Birmingham, AlabamaAges 18 years+ - NCT05363657Recruiting
Registry study for kidney tumor treatment choices
This study is a registry that collects information on how people with localized kidney tumors are treated (either active treatment or watchful waiting). It may help doctors better understand which approaches work best for different patients.
Los Angeles, CaliforniaAges 18 years+ - NCT05366881Recruiting
Blood test study to spot early cancer signal and cancer leftovers
This observational study checks whether a blood test (a “cfDNA” test) can detect early signs of cancer or small amounts of cancer left after treatment. It may help doctors use a simple blood sample to improve cancer detection and follow-up.
Duarte, CaliforniaAges 40 years+ - NCT05370014Recruiting
Study for COVID survivors and their unpaid carepartners in South Carolina
This study looks at how to improve health and support for African American adults who had COVID-19 severe enough to need urgent care or hospitalization, along with the unpaid carepartner who helps them at home. It may be helpful if you and your carepartner live in a medically underserved or rural area and share daily support needs.
Columbia, South CarolinaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,505 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,180 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.