Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT07036614Enrolling by invitation
New light tool for airway exams
This trial tests a special light device used during a lung airway exam (bronchoscopy) to help doctors see and biopsy growths more clearly. It might help people who are already scheduled for a bronchoscopy because of a spot on their chest x-ray or CT scan.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07034391RecruitingPhase 2
PD-1 inhibitor with denosumab and chemo for advanced lung cancer
This trial tests a combination of an immunotherapy drug (PD-1 inhibitor), a bone-strengthening drug (denosumab), and chemotherapy for people with advanced or spread non-squamous non-small cell lung cancer that does not have certain genetic changes. The goal is to see if this combination helps shrink tumors and control the disease.
Shenyang, LiaoningAges 18–75 - NCT07037836RecruitingPhase 2
Inhaled treprostinil for COPD with low oxygen
This trial tests an inhaled medication called treprostinil (Tyvaso) to see if it can help people with COPD who have low blood oxygen levels. You may qualify if you have chronic bronchitis, use oxygen at rest or during exercise, and meet specific lung function criteria.
Durham, North CarolinaAges 40 years+ - NCT07034326RecruitingPhase 2/Phase 3
Acupuncture plus immunotherapy after lung cancer surgery
This trial explores whether adding electroacupuncture (a gentle needle treatment with mild electric pulses) to standard immunotherapy after lung cancer surgery can help prevent the cancer from coming back. It is designed for people with early-stage non-small cell lung cancer who have already had chemotherapy.
TianjinAges 18–80 - NCT07035743Recruiting
Lung response to exercise after double lung transplant
This study looks at how your lungs respond to exercise after a double lung transplant. It aims to understand normal recovery patterns and may help improve care for other transplant recipients.
TaoyuanAges 20 years+ - NCT07043920Recruiting
Smoking and physical activity in young adults
This study looks at how smoking affects physical activity levels in healthy young adults who are studying health sciences. It may help you understand if smoking changes your daily movement.
IstanbulAges 18–30 - NCT07042035Recruiting
A study of once-daily tacrolimus for new lung transplant patients
This trial tests a special form of tacrolimus (Envarsus) taken once daily to prevent organ rejection in people who recently received a first lung transplant. The study will follow patients for at least 12 months.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07041320Recruiting
Oral chemo and immunotherapy for older adults with lung cancer
This trial is testing a combination of an oral chemotherapy pill (vinorelbine) and an immunotherapy drug (PD-1 inhibitor) for people aged 65 and older with advanced non-small cell lung cancer who have not had treatment before. The goal is to see if this approach can help control the cancer with fewer side effects.
Hefei, AnhuiAges 65 years+ - NCT07040202Recruiting
Immune system study for dengue, flu, and sepsis patients
This study looks at how the immune system responds to dengue, flu, and sepsis. It may help doctors understand these illnesses better and improve future treatments.
Kampong SpeuAges 2 years+ - NCT07040332Recruiting
Understanding allergic bronchopulmonary aspergillosis
This study looks at why some people with asthma get a lung infection from mold called aspergillus. It will help doctors better understand the condition and how to treat it.
Jinan, ShandongAges 18 years+ - NCT07039019RecruitingEarly Phase 1
Prednisone for Non-Specific Pleuritis
This trial tests if a short course of the steroid prednisone can help people with nonspecific pleuritis—inflammation of the lung lining without a known cause. If you haven't responded to other treatments, this study aims to see if prednisone is a safe and effective option.
New York, New YorkAges 18 years+ - NCT07039656RecruitingPhase 2
Toripalimab plus chemo after NSCLC surgery
This trial tests adding the immunotherapy drug toripalimab to chemotherapy after surgery for non-small cell lung cancer (NSCLC). It is for patients who either had no treatment before surgery or had chemo-immunotherapy before surgery and still have signs of cancer in their lymph nodes. The goal is to see if this combination helps prevent cancer from coming back.
Guangzhou, GuangdongAges 18–75 - NCT06629558Recruiting
A less invasive treatment for severe emphysema
This trial tests a bronchoscopic procedure to reduce lung volume in patients with severe emphysema that is patchy (not spread evenly). The goal is to help you breathe better without the need for surgery.
Al MansurahAges 40–75 - NCT06992583RecruitingPhase 1
CAR-T cell therapy for advanced CEA-positive lung cancer
This trial tests a new type of immune therapy called CAR-T cells that are designed to attack lung cancer cells with a specific marker called CEA. It may be an option for people with advanced lung cancer who have already tried other treatments.
Nanjing, JiangsuAges 18 years+ - NCT04377490Recruiting
Study of blood clots in hospitalized COVID-19 patients
This study looks at how often blood clot–related problems happen in people hospitalized with serious COVID-19 lung illness. It may help doctors understand risks and improve care for patients in the hospital.
AmiensAges 18 years+ - NCT04711746Recruiting
Clonal blood changes after certain lung blood clots
This study looks at whether a specific kind of blood-cell change (“clonal hematopoiesis”) is linked to a lung blood clot (pulmonary embolism) that happened without a clear trigger. It compares people with unprovoked clots to people with provoked clots, after checking for inherited clotting risk factors.
AmiensAges 18–65 - NCT06598527RecruitingPhase 3
Radiation and immunotherapy before surgery for lung cancer
This trial tests adding targeted radiation before standard immunotherapy and chemotherapy for people with stage 2-3 non-small cell lung cancer that can be surgically removed. The goal is to see if the radiation helps shrink the tumor more before surgery.
Guangzhou, GuangdongAges 18–75 - NCT06715280RecruitingPhase 4
Switching from sildenafil to riociguat for CTEPH
This trial tests switching from sildenafil to a newer medicine called riociguat for people with CTEPH (a type of lung blood pressure problem) who still have symptoms after a balloon procedure. The goal is to see if the switch helps them feel better.
Hong KongAges 18 years+ - NCT06720818Recruiting
Infection-fighting cells in severe lung injury
This study looks at a type of immune cell (MAIT cell) in patients with severe lung problems caused by infections, pancreatitis, head injury, burns, or major surgery. It aims to understand how these cells change during illness, which may lead to better treatments.
ToursAges 18 years+ - NCT07030881Recruiting
Spacer use in older adults with COPD or asthma on triple therapy
This trial tests whether using a spacer with your inhaler can lower the risk of serious flare-ups for people over 65 who have COPD or asthma and are already on triple therapy.
Hefei, AnhuiAges 65 years+ - NCT06808464Recruiting
Heart rate changes during sleep in severe sleep apnea
This study looks at how your heart rate changes during sleep in people with severe sleep apnea compared to healthy people. It uses a simple overnight recording to measure your nervous system activity.
LilleAges 18–64 - NCT07027514RecruitingPhase 1
Combination treatment for advanced lung cancer
This study tests a new drug called tolododekin alfa combined with an approved immunotherapy drug for people with advanced non-small cell lung cancer. The goal is to see if this combination is safe and effective.
Coral Gables, FloridaAges 18 years+ - NCT07030257RecruitingPhase 1/Phase 2
Study of CP-383 for advanced solid tumors
This study tests a new drug called CP-383 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if it can shrink tumors or slow cancer growth, especially for certain cancers with genetic changes.
Denver, ColoradoAges 18 years+ - NCT07028489Recruiting
Studying a standard-care comparison group for advanced EGFR-mutant lung cancer
This trial collects information from people with a specific type of advanced lung cancer to create a comparison group. It helps researchers understand how well new treatments work without giving any experimental medicine.
Monterey, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.