Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06247631Recruiting
Sleep apnea risk before chest surgery
This study uses a simple questionnaire (STOP-Bang) to check if patients having chest surgery might have undiagnosed sleep apnea or face breathing challenges during surgery. It helps doctors plan safer care.
Ankara, KeçiörenAges 18–65 - NCT06247605RecruitingPhase 3
Study of AL8326 for advanced small cell lung cancer
This trial tests a new oral drug called AL8326 for people with advanced small cell lung cancer who have already tried at least two other treatments. The goal is to see if the drug can shrink tumors and help patients live longer.
Changchun, JilinAges 18 years+ - NCT06247826Recruiting
Why amivantamab stops working in certain lung cancers
This study looks at how and why lung cancers with a specific EGFR mutation (exon 20 insertion) become resistant to the drug amivantamab. It collects blood and tumor samples from patients whose cancer has progressed on amivantamab to better understand resistance.
BordeauxAges 18 years+ - NCT06247800Recruiting
Virtual reality to help during chest drain placement
This trial tests whether using a virtual reality (VR) headset during a chest drain procedure can help you feel less anxious or uncomfortable. The VR shows calming scenes to distract you while the doctor inserts a small tube to drain fluid or air from around your lung.
Kuala Lumpur, Kuala LumpurAges Any age - NCT06248151Recruiting
Exercise and heart health after COVID-19
This study looks at how a single exercise session affects the heart and blood vessels in people with lasting COVID-19 symptoms. It may help understand if exercise is safe and helpful for recovery.
São PauloAges 18 years+ - NCT06248606RecruitingPhase 2
Adagrasib with brain radiation for KRAS G12C lung cancer with brain mets
This study tests a targeted pill (adagrasib) combined with focused radiation to the brain (SRS) for people with KRAS G12C-mutated lung cancer that has spread to the brain. The goal is to see if this combination can control brain tumors while treating the rest of the body.
Columbus, OhioAges 18 years+ - NCT06249282RecruitingPhase 1
Carfilzomib and sotorasib for KRAS G12C lung cancer
This trial tests a combination of two drugs: carfilzomib and sotorasib, for people with a specific type of advanced lung cancer (KRAS G12C mutation) who have already tried a KRAS-targeting drug that stopped working. The goal is to see if this new combination can shrink tumors or slow the cancer.
Duarte, CaliforniaAges 18 years+ - NCT06249373Recruiting
Low-intensity ultrasound to help new fistula mature
This study tests whether low-intensity ultrasound (LIPUS) can help a new arteriovenous fistula (AVF) in the wrist mature faster and work better for dialysis. It may be a good fit if you are an adult with a new fistula that hasn't been used yet.
Suzhou, JiangsuAges 18–75 - NCT06251310RecruitingPhase 1
Testing SW-682 in Advanced Solid Tumors
This trial tests a new drug (SW-682) for people with advanced solid tumors that have stopped responding to standard treatments. It focuses on cancers with specific gene changes (NF2 or Hippo pathway) and aims to see if the drug can shrink tumors or slow their growth.
Scottsdale, ArizonaAges 18 years+ - NCT06251687Recruiting
Cryobiopsy for diagnosing progressive pulmonary fibrosis
This trial is testing a new, less invasive way to take a lung tissue sample (called transbronchial cryobiopsy) to help diagnose progressive pulmonary fibrosis (PPF). It may help doctors find the cause of your lung scarring without needing a larger surgery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06252129Recruiting
Improving Lymph Node Removal During Lung Cancer Surgery
This trial studies a better way to remove and examine lymph nodes from lung cancer surgery specimens. It aims to improve how doctors check for cancer spread, which may help guide your treatment after surgery.
Boston, MassachusettsAges 18 years+ - NCT06252233Recruiting
Better quality of life with regular check-ins for lung cancer
This study tests whether having regular check-ins on your quality of life (like symptoms and daily well-being) can help you feel better during lung cancer treatment. It's for patients recently diagnosed with lung cancer who are getting care at select hospitals in Bavaria.
BambergAges 18 years+ - NCT06253013Recruiting
CHARM-COPD program of care after a flare-up
This study tests a program of care called CHARM-COPD for people who recently left the hospital after a COPD flare-up. It offers virtual pulmonary rehab or remote monitoring to help you recover and manage your condition at home.
Toronto, OntarioAges 40 years+ - NCT06253715RecruitingPhase 3
Shorter TB treatment for children
This trial tests a shorter treatment for children with tuberculosis (TB) that is not drug-resistant. It aims to find out if a shorter regimen works as well as the standard longer one, making treatment easier for children and their families.
ChennaiAges birth–9 years - NCT06253871RecruitingPhase 1
Study of IAM1363 for HER2 Cancers
This trial tests a new oral drug called IAM1363 for people with HER2-altered cancers that have stopped responding to previous treatments. The goal is to see if the drug is safe and how well it works against these cancers.
La Jolla, CaliforniaAges 18 years+ - NCT06254313Recruiting
Studying neutrophils in flu-related lung injury
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
BordeauxAges 18 years+ - NCT06255197Recruiting
Study of lung cancer surgery patients and their outcomes
This study looks at the characteristics, treatments, and results of people who have had surgery to remove lung cancer. It aims to help doctors understand what happens after surgery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06255626RecruitingPhase 1/Phase 2
New COVID-19 booster vaccine study
This trial tests a new type of COVID-19 booster vaccine that targets a protein to help your immune system. It's for people who already had a primary vaccine series and at least one mRNA booster, with the last booster at least 6 months ago.
CréteilAges 18–84 - NCT06256237RecruitingPhase 2
Immunotherapy plus chemo before surgery for limited-stage small cell lung cancer
This trial tests whether adding two immunotherapy drugs (toripalimab and JS004) to standard chemotherapy before surgery can help shrink limited-stage small cell lung cancer. The goal is to find better ways to treat this cancer before surgery.
ShanghaiAges 18 years+ - NCT06258642Recruiting
Irinotecan liposome plus anlotinib for SCLC after first chemo
This trial tests a combination of two drugs—irinotecan liposome (a chemotherapy) and anlotinib (a targeted therapy)—as a second treatment for small cell lung cancer that returned quickly after initial chemo. The goal is to see if this combo can work better than standard options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06259292Recruiting
HHT patient registry tracking long-term outcomes
This registry collects health information from people with HHT over time to better understand the disease and improve care. Joining does not involve any experimental treatment, but your data will help researchers learn more about HHT.
Birmingham, AlabamaAges Any age - NCT06259877Recruiting
Breathing, balance, and function after a stroke
This study tests how breathing muscle strength, balance, and trunk control relate to daily function after a stroke. It aims to help you recover better.
KirikkaleAges 18 years+ - NCT06261034Recruiting
How sex affects blood pressure control
This study looks at how the nervous system controls blood pressure differently in men and women. It may help researchers understand why some heart conditions affect men and women differently.
Rochester, MinnesotaAges 20–70
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.