Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06341231Recruiting
Personalized blood thinners for lung clots
This study tests personalized blood thinner treatments for people with blood clots in their lungs. It looks for patients who are older, have kidney problems, or have cancer, to see if adjusting the treatment helps them more.
Changsha, HunanAges 18 years+ - NCT06341972Recruiting
Recovering after breathing support: a self-help program
This study tests a self-management program to help people who felt anxious after being on a breathing machine in the ICU. It aims to improve emotional recovery and quality of life.
Baltimore, MarylandAges 18 years+ - NCT06341933Recruiting
Kidney risk after lung cancer surgery (VATS)
This study looks at why some people develop kidney problems after lung cancer surgery using small incisions (VATS). By tracking your recovery, the doctors hope to find ways to protect your kidneys during and after surgery.
Ankara, KeçiörenAges 18–65 - NCT06342752Recruiting
Breath test for early lung disease in premature babies
This trial studies a breath test to predict lung disease in very premature babies. It could help doctors start treatment earlier to prevent serious breathing problems.
Edegem, AntwerpAges birth–3 days - NCT06343064RecruitingPhase 1/Phase 2
Vebreltinib plus PLB1004 for EGFR-mutant lung cancer with MET changes
This trial tests a combination of two targeted drugs (Vebreltinib and PLB1004) for people with advanced non-small cell lung cancer that has a specific EGFR mutation and has developed MET amplification or overexpression after previous EGFR-targeted therapy. The goal is to see if this combination can help shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06344000Recruiting
Nutrition and disease progression in bronchiectasis
This study looks at how nutrition affects the course of bronchiectasis, a lung condition that causes coughing and frequent infections. It may help find ways to slow the disease down.
Wuhan, HubeiAges 18–100 - NCT06345729RecruitingPhase 3
Study of Calderasib and Pembrolizumab for Advanced Lung Cancer
This trial tests a new combination of two drugs (Calderasib and Pembrolizumab) in people with a specific type of advanced lung cancer (non-small cell lung cancer) that has a KRAS G12C mutation and high PD-L1 levels. It aims to see if this treatment can help shrink or control the cancer.
Bakersfield, CaliforniaAges 18 years+ - NCT06346938Recruiting
CT scan markers for bronchiectasis classification and outlook
This study looks at whether CT scan features can help doctors better classify bronchiectasis and predict how the disease may progress. It aims to improve understanding of the condition to guide treatment decisions.
Wuhan, HubeiAges 18–100 - NCT06347536RecruitingPhase 3
Support pack after hospital stay for COPD flare-up
This study tests whether giving a 'rescue pack' with medications after leaving the hospital helps people with COPD avoid another flare-up. It is for patients recently discharged after a COPD worsening that required a hospital stay.
BarnsleyAges 40 years+ - NCT06347939Recruiting
Lung lymph node biopsy study
This study tests a new way to take tissue samples from swollen lymph nodes in the chest using a thin tube passed through the mouth. It aims to see if this method is safe and effective.
LundAges 18 years+ - NCT06348459Recruiting
Catheter treatment for severe pulmonary embolism
This study looks at how well a catheter (a thin tube) works to treat a serious type of blood clot in the lungs. It is for people who have a large clot that is causing problems like fast heart rate or low blood pressure.
Madrid, MadridAges 18 years+ - NCT06348927RecruitingPhase 2
Sunvozertinib plus anlotinib for first-line EGFR-mutant lung cancer
This trial tests a combination of two oral drugs (sunvozertinib and anlotinib) as a first treatment for advanced lung cancer with certain EGFR mutations plus other gene changes. It aims to see if this combination works better than standard treatments.
Changsha, HunanAges 18 years+ - NCT06349174Recruiting
Lung valve treatment for severe COPD
This study tests whether placing tiny valves in the airways can help people with severe COPD breathe easier. It is for people who still have trouble breathing despite quitting smoking and completing pulmonary rehab.
Beijing, Beijing MunicipalityAges 40–85 - NCT06349642Recruiting
Testing a live tumor test for immune therapy response
This trial uses a special test on live tumor samples to see if it can predict how well immune checkpoint inhibitors (a type of immunotherapy) will work for different cancers. It may help doctors choose the best treatment for you.
Phoenix, ArizonaAges 18 years+ - NCT06350032RecruitingPhase 3
Testing treprostinil safety in children with PAH
This trial tests a medicine called treprostinil in children with severe pulmonary arterial hypertension (high blood pressure in the lungs). The study aims to see if it is safe and tolerable for kids who need this kind of therapy.
Vienna, State of ViennaAges Up to 18 years - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06351345RecruitingPhase 2
Xenon imaging study for pulmonary hypertension patients on sotatercept
This trial uses a special imaging technique (xenon MRI) to see how well the lungs are functioning in people with pulmonary arterial hypertension (PAH) who are being treated with the drug sotatercept. It aims to understand if the drug improves lung function.
Durham, North CarolinaAges 18–75 - NCT06352008RecruitingPhase 2
Anlotinib for lung cancer patients with incomplete response after chemo-immunotherapy
This trial tests if anlotinib (a targeted therapy) can help prevent lung cancer from returning after surgery for patients whose tumors did not completely disappear after chemotherapy plus immunotherapy before surgery.
TianjinAges 18 years+ - NCT06354959Recruiting
Prehab program before lung or esophageal cancer surgery
This program helps you get stronger and healthier before your lung or esophageal cancer surgery. It's called 'prehab' and aims to improve your recovery after the operation.
Halifax, Nova ScotiaAges 18 years+ - NCT06355232RecruitingPhase 1
Oral vaccine for COVID-19 and flu
This study tests an experimental oral vaccine that may protect against both COVID-19 and the flu. Researchers want to see if it's safe and how the body responds.
Adelaide, South AustraliaAges 18 years+ - NCT06355609RecruitingPhase 2
Targeted therapy for advanced EGFR-mutant lung cancer
This trial tests a combination of two targeted pills (sunvozertinib and anlotinib) as a first treatment for people with advanced lung cancer that has a specific EGFR mutation. It aims to see if this combination works better than current standard treatments.
Changsha, HunanAges 18 years+ - NCT06356246Recruiting
Oral health survey for adults with cystic fibrosis
This study uses an online survey to learn about the oral health of adults with cystic fibrosis. Your answers can help doctors understand and improve dental care for people like you.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT06357403Recruiting
Predicting blood clots in ICU patients with a blood test
This study looks at whether a blood test measuring a substance called anti-factor Xa activity can help predict dangerous blood clots in critically ill patients. If you join, researchers will follow you to see if the test results can prevent clots.
Graz, StyriaAges 18 years+ - NCT06357780Recruiting
Comparing two breath-timing methods for breathing masks in adults
This study compares two ways of timing a breathing mask's support to match your own breaths. If you're in the ICU or ER and need help breathing for at least 2 more hours, this trial may test which method works better.
IzmirAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.