Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06358222Recruiting
Lung cancer trial testing blood test and PET scan for spread
This trial studies if a blood test that looks for tumor DNA combined with a PET-CT scan can better predict if lung cancer has spread to lymph nodes. It may help guide treatment decisions for people with non-small cell lung cancer that hasn't been treated yet.
ShanghaiAges 18–75 - NCT06360627Recruiting
Low-dose CT with contrast for lung checks
This study tests a special low-radiation CT scan with a contrast dye called Iomeron 400 to see if it works well for checking lung nodules or pneumonia.
ZurichAges 18 years+ - NCT06360393Recruiting
Checking inhaler use with a smart spacer for severe asthma on biologics
This trial tests if a smart spacer can help people with severe asthma use their inhaler correctly and stick to their medication schedule. It’s for adults already taking biologic drugs for asthma.
Zwolle, OverijsselAges 18 years+ - NCT06360822Recruiting
Making lung cancer screening fair for everyone
This trial is testing a program to make lung cancer screening more fair and available. If you're eligible, you may be offered a free or low-cost screening to check for lung cancer early, which could improve treatment options.
Indianapolis, IndianaAges 50–80 - NCT06362343Recruiting
Personalized dosing study for Xa inhibitor blood thinners
This study looks at how the body processes a certain type of blood thinner (Xa factor inhibitors) to help doctors find the right dose for each person. If you have a blood clot in your lungs and are on long-term treatment, this trial might help improve your care.
Beijing, Beijing MunicipalityAges 18–120 - NCT06362122Recruiting
Severe nasal polyps: links between symptoms, tissue, and blood
This study looks at people with severe nasal polyps that need surgery (ethmoidectomy) for the first time. Researchers want to understand the connection between your symptoms, nasal tissue, and blood tests.
PoitiersAges 18 years+ - NCT06362369RecruitingPhase 1/Phase 2
Oral 7HP349 with immunotherapy for advanced solid tumors
This trial tests an experimental oral drug (7HP349) combined with two immunotherapy drugs (ipilimumab and nivolumab) for people with advanced solid tumors. It aims to see if the combination is safe and effective in shrinking tumors.
Aurora, ColoradoAges 18 years+ - NCT06362382Recruiting
Home rehab via smartphone for pulmonary hypertension
This study tests whether a home-based exercise program, guided by a smartphone app, can improve your daily life and heart function if you have pulmonary hypertension. You will use a wearable device to track your activity and receive remote support from a medical team.
Beijing, Beijing MunicipalityAges 18–60 - NCT06362746RecruitingPhase 3
Staphylokinase for intermediate high-risk pulmonary embolism
This trial tests a new drug, staphylokinase, to see if it can break up blood clots in the lungs in people with a moderate-high risk pulmonary embolism. The goal is to improve blood flow and reduce the chance of complications.
Barnaul, Altayskiy KrayAges 18 years+ - NCT06363734RecruitingPhase 2
Targeted drug combo for EGFR-mutant lung cancer after resistance
This trial tests a combination of two targeted drugs (osimertinib and dalpiciclib) for people with advanced lung cancer whose tumors have a specific EGFR mutation and a change in the CDK4/6 pathway, and whose cancer has stopped responding to a third-generation EGFR targeted therapy. The goal is to see if this combination can help shrink tumors or slow cancer growth.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06364176RecruitingPhase 2
Adding losartan to improve Trikafta response in CF
This study tests whether adding the blood pressure medication losartan can help the standard CF drug Trikafta work better by reducing inflammation. It's for people with CF who still have high sweat chloride levels despite taking Trikafta.
Kansas City, KansasAges 12 years+ - NCT06364514Recruiting
Antibiotic course study for kids with complex medical needs
This study looks at how long children with complex medical conditions need to take antibiotics for pneumonia. The goal is to find a patient-centered approach to treatment that works best for each child.
Boston, MassachusettsAges 2–25 - NCT06364917RecruitingPhase 2
Comparing two immunotherapy options for PD-L1 negative lung cancer
This trial tests whether using two immunotherapy drugs together works better than a single drug for people with advanced non-small cell lung cancer that does not have the PD-L1 protein. The study aims to find a more effective treatment for this specific type of lung cancer.
Birmingham, AlabamaAges 18–89 - NCT06366113Recruiting
Morning vs. afternoon exercise for COPD rehab
This study tests whether the time of day you exercise (morning vs. afternoon) affects how much you improve during a COPD rehabilitation program. It may help you get the most benefit from your rehab sessions.
LilleAges 18–85 - NCT06366724RecruitingPhase 2
Life Improvement Trial for ME/CFS
This trial tests a new treatment for ME/CFS (chronic fatigue syndrome) that includes symptoms like dizziness when standing. It uses a smartphone app to track your progress and aims to see if the treatment can improve your daily life.
Boston, MassachusettsAges 18–70 - NCT06367400Recruiting
Validating a Sleep Questionnaire for Swedish Children
This study tests a sleep questionnaire designed to help diagnose sleep-related breathing problems in children. It aims to see if the questionnaire works well for Swedish children, making it easier for doctors to spot these issues early.
UppsalaAges 1.5 years–15 years - NCT06367946Recruiting
Why ventilators can hurt older lungs
This study looks at how mechanical ventilation affects the lungs of elderly people. Researchers will study lung tissue and blood samples from patients having surgery to find ways to prevent lung injury.
ShanghaiAges Any age - NCT06368804RecruitingPhase 2
Comparing two antibiotics for early PA infection in bronchiectasis
This trial tests two different antibiotic treatments for adults with bronchiectasis who have a new or recent infection with Pseudomonas aeruginosa (PA) bacteria in their airways. The goal is to see which regimen works better to clear the infection early.
AmiensAges 18 years+ - NCT06369181Recruiting
Study on cell changes in lung cancer with RB1/TP53 gene changes
This trial looks at what happens when certain types of non-small cell lung cancer—those with changes in the RB1 and TP53 genes—start to change into another type of lung cancer after treatment. It may help find better ways to treat this specific kind of cancer in the future.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06370832Recruiting
Breathing muscle training for people waiting for a lung transplant
This study tests if a special breathing exercise (inspiratory muscle training) can strengthen your breathing muscles while you wait for a lung transplant. You'd do the training alongside your regular pulmonary rehab sessions.
Edmonton, AlbertaAges 18 years+ - NCT06370962Recruiting
Sleep study for children with cystic fibrosis on Kaftrio-Kalydeco
This study looks at sleep and daily activity rhythms in children with cystic fibrosis who are taking a medication called Kaftrio-Kalydeco. It aims to understand if the medication affects sleep patterns and how to improve them.
BronAges 2–17 - NCT06372249RecruitingPhase 2
Fiber drink for asthma in kids
This trial tests whether a liquid fiber drink can help children with asthma by reducing airway inflammation. Participants will drink either fiber or a placebo and be followed for about 4–6 weeks to see if their asthma improves.
Phoenix, ArizonaAges 6–17 - NCT06372730Recruiting
Predicting blood clot return after stopping blood thinners
This study uses a special 3D lung scan (V/Q SPECT/CT) to see if leftover blockages in your lungs can predict if another blood clot will come back. You may be eligible if your doctor has decided it's safe to stop your blood thinners after 3 to 6 months of treatment for a first blood clot.
Amiens, FranceAges 18 years+ - NCT06372847Recruiting
Sleep apnea nerve stimulation study
This trial tests a nerve-stimulation implant for sleep apnea when other treatments haven't worked. It may help if you have moderate to severe apnea, a BMI under 32, and have tried CPAP and a mouth device without success.
Edegem, AntwerpenAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.