Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06987214RecruitingPhase 1
Regenerative stem cell therapy for bronchiectasis
This trial tests whether transplanting your own lung stem cells can repair damaged airways caused by bronchiectasis. It is for people with moderate to severe breathing impairment and aims to improve lung function.
Qionghai, HainanAges 25–80 - NCT06992739RecruitingPhase 2
Trilaciclib with chemotherapy for EGFR-mutant advanced lung cancer
This study tests whether adding trilaciclib to a new chemotherapy (sacituzumab tirumotecan) can help people with EGFR-mutant lung cancer that keeps growing after certain targeted treatments. The goal is to see if it slows the cancer and reduces side effects.
Xiamen, FujianAges 18–75 - NCT06992440RecruitingPhase 2
Empagliflozin for better right heart function in pulmonary hypertension
This trial tests if a diabetes drug can help people with pulmonary arterial hypertension whose right heart function is reduced. Participants take empagliflozin or a placebo for 24 weeks to see if heart function improves.
Baltimore, MarylandAges 18 years+ - NCT06989385Recruiting
Studying breathing support failure in respiratory failure
This study looks at why some patients with acute respiratory failure do not improve with non-invasive breathing support like high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV). It aims to find patterns that might predict when these treatments are not enough.
ModenaAges 18 years+ - NCT06986343Enrolling by invitation
Palatal expansion and activator device for sleep in children
This trial tests if a palatal expander combined with an Up-Locker activator can improve sleep and open up the airway in children with sleep-disordered breathing. It may help kids who snore and have a narrow upper jaw.
Medellín, AntioquiaAges 6–8 - NCT06983821RecruitingPhase 3
Low-dose steroids for kidney disease from vasculitis
This trial tests lower steroid doses for people with certain types of vasculitis that have newly affected their kidneys. The goal is to find out if a lower dose works just as well with fewer side effects.
Hamilton, OntarioAges 18 years+ - NCT06988579Recruiting
AI-assisted lung cancer screening study
This trial tests whether using AI to help radiologists read lung CT scans can find cancer earlier and lower healthcare costs. You may qualify if you are at risk for lung cancer and have not been screened recently.
Guangzhou, GuangdongAges 40–74 - NCT06983366Recruiting
Lung sliding index for diagnosing lung conditions
This study uses an ultrasound-based measurement called the Lung Sliding Index to help tell different lung diseases apart. Researchers want to see if it can be a useful and simple tool for doctors.
AsyutAges 18 years+ - NCT06992661RecruitingPhase 1
Inhaled RJ026 study for interstitial lung disease patients
This trial tests a single inhaled dose of RJ026 in patients with interstitial lung disease (ILD), including idiopathic pulmonary fibrosis (IPF) or connective tissue disease-related ILD (CTD-ILD). It helps see how the drug moves through the body and if it's safe.
Shanghai, Shanghai MunicipalityAges 40 years+ - NCT06985225Recruiting
Study of mucus plugs and lung function in mucus-related lung disease
This study looks at how mucus plugs affect air flow in the lungs. It may help find new ways to treat people with lung conditions like cystic fibrosis, severe asthma, COPD, or bronchiectasis.
Kansas City, KansasAges 18–65 - NCT06991361RecruitingPhase 1
Expanded immune cells and low-dose IL-2 for chronic GVHD
This trial tests whether giving special immune cells (regulatory T cells) grown in a lab, along with a low dose of interleukin-2, can help people with chronic graft-versus-host disease (GVHD) that hasn't improved with steroids. GVHD is a complication after a stem cell transplant where donor cells attack the patient's body.
Boston, MassachusettsAges 2 years+ - NCT06987890Recruiting
Geriatric assessment for older adults with lung cancer getting SBRT
This study looks at how a geriatric assessment can help older adults with early-stage lung cancer who are getting a precise type of radiation therapy called SBRT. The goal is to understand their needs and improve care.
Boston, MassachusettsAges 65 years+ - NCT06986148Recruiting
Comparing antibiotics for childhood pneumonia in clinics
This trial compares different antibiotic strategies for children with pneumonia who are being treated as outpatients. The goal is to find the best approach to treat the infection and help your child recover.
Atlanta, GeorgiaAges 1 year–5.9 years - NCT06984679Recruiting
Physical function study for kids with cystic fibrosis
This trial compares physical abilities between children with cystic fibrosis and healthy children. It aims to find differences that could lead to better care and therapies.
IzmirAges 6–18 - NCT06990477Recruiting
EIT-guided breathing machine settings for ARDS
This trial tests a special monitoring technique called EIT (electrical impedance tomography) to help doctors set the best breathing machine pressure for people with ARDS. It may help improve oxygen levels and protect the lungs.
Hefei, AnhuiAges 19–90 - NCT06983899Recruiting
Exercise to boost immunity during lung cancer immunotherapy
This trial tests whether a supervised exercise program can help improve immune activity and treatment outcomes for people with non-small cell lung cancer who are already on immunotherapy. It is designed for people who are not currently very active.
Seattle, WashingtonAges 18 years+ - NCT06987266Recruiting
Study of lung and airway disease diagnosis
This study aims to improve how doctors diagnose and classify lung conditions that affect both the air sacs and airways, such as COPD and pulmonary fibrosis. By participating, you may help advance medical knowledge and better understand your own condition.
Changsha, HunanAges 40–80 - NCT06986187Recruiting
Predicting difficult airways in heart surgery patients
This study measures how often difficult airways occur during heart or blood vessel surgery and builds a way to predict them beforehand. It may help your care team prepare for safer airway management during your procedure.
AnkaraAges 18 years+ - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT06988111Recruiting
Breathing support after major surgery
This trial tests two types of non-invasive breathing help (NIV and HVNI) for patients who develop serious breathing problems within two days after major surgery. It aims to see which method works better to avoid needing a breathing tube.
Asyut, AssuitAges 18 years+ - NCT06986993RecruitingPhase 4
Semaglutide for smoking and weight in people with obesity
This study tests whether the medication semaglutide (similar to Ozempic/Wegovy) can help people who smoke and have obesity cut down on cigarettes, even if they aren't ready to quit. Participants will receive the drug and be monitored for changes in smoking habits and health.
Oklahoma City, OklahomaAges 18–65 - NCT06983769Recruiting
CPAP vs Mouthpiece for Sleep Apnea in Patients with Memory Issues
This study compares two treatments for sleep apnea (CPAP and a custom mouthpiece) to see which is better for patients who also have mild memory or thinking problems. Sleep apnea is a condition where breathing stops and starts during sleep. You may qualify if you have moderate-to-severe sleep apnea and mild cognitive impairment.
Kent Ridge, Please SelectAges 45 years+ - NCT06867354Recruiting
Breathing difficulty in obese patients during weaning from ventilator
This study looks at how often obese patients have trouble breathing when doctors try to remove the breathing tube (weaning) in the ICU. The goal is to understand what causes this and how it affects recovery.
Paris, ParisAges 18 years+ - NCT06724315Recruiting
Studying severe COPD in Brazil
This study follows people with severe or very severe COPD to learn more about their health over time. You may qualify if your COPD causes many symptoms or frequent flare-ups.
São Paulo, São PauloAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.