Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07201051RecruitingPhase 2
Testing a new drug for people with bronchiectasis
This trial tests if a new drug, GSK3862995B, is safe and effective for adults with bronchiectasis. It might help reduce lung infections and improve symptoms.
Mobile, AlabamaAges 18–85 - NCT01915511Recruiting
Long-term registry for new or worsening lung scarring
This study collects health information over time from people with newly diagnosed idiopathic pulmonary fibrosis (IPF) or other lung scarring diseases that are getting worse. It’s meant to better understand disease patterns and outcomes, which may help doctors plan future care.
Birmingham, AlabamaAges 21 years+ - NCT05890612Recruiting
Study of Paxlovid safety and effectiveness in high-risk COVID-19
This study observes people at higher risk for severe COVID-19 who take Paxlovid, to better understand how well it works and how safe it is in real-world use. It may help doctors confirm the best way to use Paxlovid and spot any side effects.
SeoulAges 19 years+ - NCT07566611Recruiting
Ciliary Function in Adults with Bronchiectasis
This study looks for signs of ciliary dyskinesia (a condition affecting tiny hair-like structures in the lungs) in adults who have bronchiectasis (damaged airways). Understanding this connection may help doctors better treat and manage your lung disease.
Indianapolis, IndianaAges 18 years+ - NCT07743996Recruiting
Emotional and social experiences with fibrosis medications
This study looks at how people with pulmonary fibrosis feel emotionally and socially while taking antifibrotic medications like nintedanib or pirfenidone. It aims to understand the real-world impact of these treatments on daily life.
TokyoAges 40 years+ - NCT07455396RecruitingPhase 2
Dexamethasone vs methylprednisolone for children with severe asthma
This trial compares two steroids, dexamethasone and methylprednisolone, to see which works better for children in the intensive care unit with severe asthma. The goal is to find the best treatment with fewer side effects.
St. Petersburg, FloridaAges 3–17 - NCT07730034Recruiting
Early physical therapy after heart surgery to prevent breathing problems
This trial tests whether starting physical therapy soon after planned heart surgery can help prevent breathing complications. It is for adults who are having a first-time coronary artery bypass grafting (CABG) and meet specific health criteria.
ZagrebAges 18–80 - NCT05552846Recruiting
Radiation to the chest after chemo-immunotherapy for small cell lung cancer
This trial looks at whether giving additional targeted radiation to the chest can help people with extensive-stage small cell lung cancer after they finish standard chemo-immunotherapy. It may help control the cancer in the lung area and prevent it from coming back there.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07490860Recruiting
Supporting Black adults to decide about lung cancer screening
This study tests a program called RESTORE that helps Black adults who smoke make informed decisions about lung cancer screening. The program uses restorative justice principles to support you in talking with your doctor.
Seattle, WashingtonAges 50–77 - NCT06357533RecruitingPhase 3
New drug combo for advanced lung cancer with high PD-L1
This trial tests a new two-drug combination (Dato-DXd and an immunotherapy called rilvegostomig) as the first treatment for people with advanced non-squamous lung cancer who have high PD-L1 levels. The goal is to see if this combination works better than current standard options.
Anchorage, AlaskaAges 18 years+ - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT07146568Recruiting
Pink and Pearl Lung Cancer Screening Study
This trial is testing a program called the Pink and Pearl Campaign to help more people get screened for lung cancer. If you're getting a mammogram at Christian Hospital and are between 50 and 80, you might be able to join.
St Louis, MissouriAges 20 years+ - NCT07610395RecruitingPhase 2
Testing an oral drug for cold virus in COPD patients
This trial tests an oral medication (VPV) to see if it can safely treat rhinovirus (a common cold virus) in people with COPD. The goal is to help you recover faster and prevent serious COPD flare-ups.
Mobile, AlabamaAges 40–85 - NCT05145244Recruiting
Copenhagen observational study for lung or breast cancer data
This is an observational study that collects real-world information from adults with lung cancer or breast cancer. It may help doctors better understand how people do over time and how treatments and outcomes relate to details from your medical record and tests.
CopenhagenAges 18 years+ - NCT05099172RecruitingPhase 1/Phase 2
Study drug for EGFR or HER2-mutated advanced lung cancer
This early-phase study tests a new investigational medicine (BAY2927088) in people with advanced non-small cell lung cancer (NSCLC) that has EGFR and/or HER2 mutations. It’s designed to see how the drug works and what side effects it causes, when standard options have not helped or aren’t suitable.
Gilbert, ArizonaAges 18 years+ - NCT07535008Recruiting
Dental Cleaning to Prevent Graft-Versus-Host Disease
This study tests whether professional dental cleaning after a stem cell transplant can help prevent chronic graft-versus-host disease (GVHD), a condition where transplanted immune cells attack your body. You'll receive dental cleanings and be followed for one year to see if this simple preventive step reduces GVHD complications.
Seattle, WashingtonAges 18 years+ - NCT06526819RecruitingPhase 1/Phase 2
New drug SMP-3124LP for advanced solid tumors
This trial tests a new drug called SMP-3124LP for people with advanced solid tumors that no longer respond to standard treatments. It is given in two phases: first to find the best dose (dose escalation) and then to see how well it works in specific cancer types (dose expansion).
Los Angeles, CaliforniaAges 18 years+ - NCT07697586RecruitingPhase 2
Two new drugs for advanced lung cancer without EGFR or ALK
This trial tests a combination of two new drugs, SKB264 and SKB118, for people with advanced non-small cell lung cancer. It may be an option if your cancer does not have the EGFR or ALK gene changes and you are in relatively good health.
Jilin CityAges 18–75 - NCT05847894Recruiting
AI eye scans to help diagnose lung breathing problems
This trial tests an artificial intelligence (AI) tool that uses eye images to help doctors diagnose breathing or lung-related conditions. If you have a lung/breathing problem and can do both eye and lung checkups, it may support faster or more accurate diagnosis.
Guangzhou, GuangdongAges Any age - NCT06476132RecruitingPhase 2
Belumosudil for lung transplant patients at risk of chronic rejection
This trial tests whether the drug Belumosudil can help prevent chronic lung rejection in people who recently had a lung transplant and showed signs of early rejection. It may improve long-term lung health.
Los Angeles, CaliforniaAges 12 years+ - NCT06475781RecruitingPhase 2
Study of mirivadelgat for pulmonary hypertension with interstitial lung disease
This study tests a new medication called mirivadelgat for people with pulmonary hypertension associated with interstitial lung disease (PH-ILD). The goal is to see if it can help improve symptoms and slow the progression of the disease.
Hualien City, TaiwanAges 18–85 - NCT06807632RecruitingPhase 1
Study of two drugs for extensive-stage small cell lung cancer
This trial tests a new combination of two drugs (valemetostat and atezolizumab) for people with extensive-stage small cell lung cancer who have already responded to initial chemo-immunotherapy. The goal is to see if adding valemetostat can keep the cancer from growing longer.
Basking Ridge, New JerseyAges 18 years+ - NCT07757542RecruitingPhase 2
Hydrogen gas for mild cognitive impairment
This trial tests whether breathing in a small amount of hydrogen gas is safe and might help people with mild cognitive impairment. It aims to see if this simple approach could support brain health.
Ostrava, Moravian-Silesian RegionAges 50–80 - NCT06477952RecruitingPhase 1/Phase 2
Dronabinol for sleep apnea
This study tests whether dronabinol, a cannabis-like medicine, can help people with moderate sleep apnea breathe better at night. It may be an option for those who haven't found other treatments helpful.
Chicago, IllinoisAges Up to 65 years
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.