Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT04430790RecruitingPhase 3
Doxapram for apnea in very preterm babies on breathing support
This trial studies whether the medicine doxapram can better treat breathing pauses (apnea) in very preterm babies who are already on breathing support in the NICU. It aims to reduce the need for extra interventions and improve outcomes in this high-risk group.
Brussels, Avenaue Hippocrate 10Ages 5 months–7 months - NCT06280443Recruiting
Frailty and muscle loss in chronic lung disease
This study looks at people with COPD or ILD who also show signs of frailty. It aims to understand how frailty and muscle loss (sarcopenia) affect their care and use of medical resources over time.
TaichungAges 20 years+ - NCT06223711RecruitingPhase 2
Durvalumab with radiation therapy for limited-spread small cell lung cancer
This trial tests a combination of durvalumab (immunotherapy) plus radiation and chemotherapy for people with extensive-stage small cell lung cancer that has only a few distant spots. The goal is to see if this approach helps control the cancer better.
Augsburg, BavariaAges 18 years+ - NCT04158479Recruiting
Registry for people on ECMO life support
This registry collects information about people who are placed on ECMO, a heart-lung machine used to support breathing and/or circulation. It may help doctors better understand who benefits and how to manage ECMO in the future.
Beijing, Beijing MunicipalityAges Any age - NCT05660460Recruiting
COPD street-level study in Denmark
This study looks at chronic lung disease (COPD) and how it affects people in everyday life. It may help researchers understand what support works best, using follow-up through Denmark’s health records.
CopenhagenAges 18 years+ - NCT05963061Recruiting
CML real-world patient data for people with chronic CML
This trial is a real-life study that collects information from people living with chronic myeloid leukemia (CML). It may help doctors understand how CML treatments are used in practice and how well they work over time.
AnnecyAges Any age - NCT06361459Recruiting
Quit Smoking Before Spine Surgery
This study tests whether a program to help people quit smoking before spine surgery improves recovery. It's for adults having neck or low back surgery, but not for cancer or trauma cases.
Leiden, South HollandAges 18–75 - NCT06360627Recruiting
Low-dose CT with contrast for lung checks
This study tests a special low-radiation CT scan with a contrast dye called Iomeron 400 to see if it works well for checking lung nodules or pneumonia.
ZurichAges 18 years+ - NCT06297005Recruiting
E-cigarette use in pregnancy and child health study
This study looks at how using e-cigarettes during pregnancy might affect children's health. If you are pregnant, smoke or vape, or are a non-smoker, you may be able to join and help us learn more.
DublinAges 18–46 - NCT06362343Recruiting
Personalized dosing study for Xa inhibitor blood thinners
This study looks at how the body processes a certain type of blood thinner (Xa factor inhibitors) to help doctors find the right dose for each person. If you have a blood clot in your lungs and are on long-term treatment, this trial might help improve your care.
Beijing, Beijing MunicipalityAges 18–120 - NCT06361589Recruiting
Lorlatinib for advanced ALK-positive lung cancer
This study is testing a targeted therapy called lorlatinib in people with advanced ALK-positive lung cancer. It aims to see how well this oral medication works in a real-world setting.
Chengdu, SichuanAges 18 years+ - NCT06367946Recruiting
Why ventilators can hurt older lungs
This study looks at how mechanical ventilation affects the lungs of elderly people. Researchers will study lung tissue and blood samples from patients having surgery to find ways to prevent lung injury.
ShanghaiAges Any age - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT06367400Recruiting
Validating a Sleep Questionnaire for Swedish Children
This study tests a sleep questionnaire designed to help diagnose sleep-related breathing problems in children. It aims to see if the questionnaire works well for Swedish children, making it easier for doctors to spot these issues early.
UppsalaAges 1.5 years–15 years - NCT06363734RecruitingPhase 2
Targeted drug combo for EGFR-mutant lung cancer after resistance
This trial tests a combination of two targeted drugs (osimertinib and dalpiciclib) for people with advanced lung cancer whose tumors have a specific EGFR mutation and a change in the CDK4/6 pathway, and whose cancer has stopped responding to a third-generation EGFR targeted therapy. The goal is to see if this combination can help shrink tumors or slow cancer growth.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT02889666RecruitingPhase 1
Chemo plus surgery for recurrent lung cancer
This Phase 1 trial tests whether giving chemotherapy along with surgery is safe and tolerable for people with recurrent non-small cell lung cancer. It may help guide future treatment for cancer that has returned, especially if it has not spread to distant sites.
Changchun, JilinAges 18–75 - NCT06169956Recruiting
Study of nivolumab with chemo before lung cancer surgery
This study looks at how well the immunotherapy drug nivolumab (Opdivo) works when given with standard chemotherapy before surgery for people with a certain type of lung cancer that has not spread. It may help shrink the tumor before surgery.
Kempten (Allgäu), BavariaAges 18 years+ - NCT04706390Recruiting
Study compares immune response after COVID infection vs vaccination
This study looks at how your immune system responds after natural COVID-19 infection compared with after COVID vaccination. It may help researchers understand how well different experiences train the body’s defenses.
BergenAges 20–100 - NCT01600378Recruiting
A study to collect health data in lung disease
This study follows adults who have suspected diffuse lung disease (abnormal changes in multiple areas of the lungs) and collects health information over time. It may help doctors better understand these lung conditions and how they progress.
SingaporeAges 21–90 - NCT04137133Recruiting
Precision medicine study for young children with cystic fibrosis
This study enrolls newly diagnosed infants with cystic fibrosis to follow them during “precision medicine” care. It may help doctors better understand which treatments and monitoring work best, especially before certain infections develop.
RoscoffAges Up to 18 years - NCT06378892RecruitingPhase 2
Study of chemo plus lorlatinib for ALK+ lung cancer
This trial tests combining chemotherapy with lorlatinib for people with ALK-positive lung cancer that has spread outside the brain while on lorlatinib. The goal is to see if adding chemo can help control the cancer when it starts growing again.
AvianoAges 18 years+ - NCT06369181Recruiting
Study on cell changes in lung cancer with RB1/TP53 gene changes
This trial looks at what happens when certain types of non-small cell lung cancer—those with changes in the RB1 and TP53 genes—start to change into another type of lung cancer after treatment. It may help find better ways to treat this specific kind of cancer in the future.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04565483RecruitingPhase 4
Test a blood-test signature to predict benralizumab benefit
This trial studies whether a specific “signature” from asthma tests can predict who will respond to benralizumab (a severe asthma biologic). If you qualify, the researchers will compare your test results to how well benralizumab controls your asthma and prevents flare-ups.
Aix-en-ProvenceAges 18–75 - NCT05110066Recruiting
Compare two procedures for chronic lung blood-clot pressure
This study compares balloon pulmonary angioplasty versus pulmonary endarterectomy for people with chronic thromboembolic pulmonary hypertension (high blood pressure in the lungs due to long-lasting blood clots). It may help find which procedure works better for improving symptoms and lung circulation after treatment.
AarhusAges 18–79
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.