Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06515990RecruitingPhase 1/Phase 2
DM005 for Advanced Solid Tumors
This study tests a new drug called DM005 for people with advanced solid tumors (like lung, stomach, colon, liver, pancreas, or head and neck cancer) that have not responded to or can't tolerate standard treatments. The goal is to see if DM005 is safe and how well it works.
Detroit, MichiganAges 18 years+ - NCT07638735Enrolling by invitation
Greener asthma inhaler prescribing tool
This study tests a tool that helps doctors choose asthma inhalers that are better for the environment. It may help your clinic reduce its carbon footprint while keeping your patients' asthma well managed.
Toronto, OntarioAges 16 years+ - NCT07730450RecruitingPhase 4
COVID-19 vaccine study for healthy adults aged 18 to 64
This trial tests a COVID-19 vaccine in healthy adults to see how well it works. It may be an option if you are not at higher risk for severe COVID-19 and have not had COVID-19 in the past 6 months.
Walnut Creek, CaliforniaAges 18–64 - NCT07575763Recruiting
CT scan vs standard sizing for breathing tubes in chest surgery
This study compares two methods for choosing the right size breathing tube for lung surgery: one uses a CT scan beforehand, the other uses standard sizing. The goal is to see which method works better and causes fewer complications.
AmmanAges 18 years+ - NCT06471257RecruitingPhase 3
Study of PT027 vs PT007 in Chinese Adults with Asthma
This study tests a new combination inhaler (budesonide/albuterol) against another asthma inhaler in adults whose asthma is not well controlled on their current medications. It aims to see if the new inhaler can reduce serious asthma attacks and improve symptoms.
BaotouAges 18 years+ - NCT07684820RecruitingPhase 2
A study of ExPD-101 for COPD with chronic bronchitis and frequent flare-ups
This study tests an experimental drug (ExPD-101) given daily as a pill for 52 weeks for people with COPD who have chronic bronchitis and frequent flare-ups. It compares the drug to a placebo (inactive pill) to see if it reduces flare-ups and improves symptoms.
Phoenix, ArizonaAges 40–85 - NCT06638073Recruiting
Continuous vitals monitoring after non-cardiac surgery
This study tests a new device that tracks your vital signs (like heart rate and oxygen levels) continuously after surgery, even when you go home. It may help doctors catch problems early and improve your recovery.
Vancouver, British ColumbiaAges 19 years+ - NCT06637280Recruiting
High-flow oxygen vs standard oxygen during lung ultrasound
This trial compares two ways of delivering oxygen during a procedure called endobronchial ultrasound (EBUS), which helps doctors look at your lungs and take samples. The goal is to see if high-flow oxygen through a mask works better than the standard low-flow nasal prongs for keeping your oxygen levels stable.
Zagreb, City of ZagrebAges 18 years+ - NCT06636890Enrolling by invitation
Testing a new method for detecting certain bacteria in lung infections
This study checks if a special test (Xpert Carba-R) can find a type of drug-resistant bacteria, called CRE, in fluid from the lungs and in rectal swabs. It might help doctors treat lower respiratory tract infections more effectively.
Nanjing, JiangsuAges 18–90 - NCT06619626Recruiting
Lung opening technique in obese women having gynecologic cancer surgery
This trial tests a lung opening technique (alveolar recruitment) during surgery to improve breathing in obese patients. It may help women with a moderate risk of breathing problems after gynecologic cancer surgery.
IstanbulAges 18 years+ - NCT06601036Recruiting
Sevoflurane sedation for difficult airway patients
This study is testing a sedative medicine (sevoflurane) to help people with a difficult airway breathe more easily during a procedure. It may be an alternative to being awake while a tube is placed in your windpipe.
Tanta, El-GharbiaAges 18–50 - NCT06566703Recruiting
Testing a program to help quit smoking in tribal communities
This study tests a program called ANSOS to help people who smoke and are American Indian quit. You'd take part in Zoom sessions and be in the study for one year to see how well the program works.
Bethlehem, PennsylvaniaAges 18 years+ - NCT06558630Recruiting
Emergency room airway management in the Netherlands
This study looks at how breathing tubes and other airway care are done in emergency rooms across the Netherlands. It will include anyone who needs help breathing while in the ER, so doctors can learn from their experience.
LeeuwardenAges Any age - NCT06534385Recruiting
Clean Air Study: HEPA Purifiers for Health
This study tests whether HEPA air purifiers can improve indoor air quality and health in rural Alaska homes that use woodstoves or have a smoker. If you join, you'll receive a purifier and help researchers see if cleaner air makes a difference.
Bethel, AlaskaAges Up to 5 years - NCT06514690Recruiting
Memories after sedation for difficult airway intubation
This study looks at whether people remember anything during sedation for a breathing tube placement when they have a difficult airway. It uses a special camera scope to help guide the tube.
Barcelona, CataloniaAges 18 years+ - NCT06500117Recruiting
Mindfulness app for quitting smoking
This trial tests a digital mindfulness program on your smartphone to help you quit smoking and stay smoke-free. It's for adults who have a smoking-related health problem and are motivated to stop.
DijonAges 18 years+ - NCT06491290Recruiting
Florence ER visits and local air quality study
This study looks at how air quality and weather in Florence affect how many people come to the emergency room. By joining, you help researchers understand if outdoor conditions like pollution or temperature might be linked to health problems.
FlorenceAges 14 years+ - NCT06483529Recruiting
Measuring lung function in ventilated patients
This trial is testing a new way to measure how your lungs are working while you are on a ventilator. It uses a gentle, low-frequency wave to check your lung function without any extra stress.
Jette, Brussel Hoofstedelijk GewestAges 18 years+ - NCT06479655RecruitingPhase 4
Comparing fentanyl and morphine for ICU sedation
This study compares two different pain and sedation medicines (fentanyl and morphine) given continuously through an IV to help patients who are on a breathing machine (ventilator) in the ICU. The goal is to see which medicine works better and is safer for keeping you comfortable and calm.
Kota Bharu, KelantanAges 18 years+ - NCT06457789Recruiting
PET scans to track immune response in lung cancer treatment
This study uses special PET scans to see how well your immune cells respond to immunotherapy given before surgery for non-small cell lung cancer. The goal is to learn which patients benefit most from this treatment approach.
Amsterdam, North HollandAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT06372899Recruiting
Switching to E-cigarettes or Nicotine Pouches for Smokers
This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.
Philadelphia, PennsylvaniaAges 21 years+ - NCT06372106Recruiting
Oxygen sensor accuracy in ICU patients
This trial checks how well a standard pulse oximeter (SpO2) on the skin matches oxygen levels measured directly from an artery (SaO2). It may help determine if the sensor is accurate for patients in intensive care.
Phoenix, ArizonaAges Any age - NCT06359652Recruiting
Get Fit for Function: Exercise before lung surgery
This study tests a program to help you get stronger before lung surgery. It may improve your recovery after the operation.
Chicago, IllinoisAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.