Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT04322617RecruitingPhase 2/Phase 3
Anlotinib plus immunotherapy for lung cancer after first treatment
This trial studies an oral targeted medicine (anlotinib) combined with an immunotherapy (checkpoint inhibitor) for lung cancer that did not respond to first-line chemo-immunotherapy. It may help shrink tumors and improve disease control after standard treatment has failed.
Changsha, HunanAges 18 years+ - NCT05059951Recruiting
Chemotherapy With or Without Immunotherapy for Lung Cancer
This trial looks at whether adding an immunotherapy drug (an immune checkpoint inhibitor) to chemotherapy helps people with lung cancer live better or respond better. You might be considered if your cancer is confirmed, you can tolerate treatment, and imaging shows measurable spots.
Changsha, HunanAges 18 years+ - NCT06440954RecruitingPhase 2
Pemetrexed injected into spinal fluid for lung cancer that spread to brain lining
This study tests a treatment called intrathecal pemetrexed, which is chemotherapy given directly into the fluid around your brain and spine. It's for people with a specific type of lung cancer that has spread to the lining of the brain or spinal cord after targeted therapy stopped working.
Changsha, HunanAges 18 years+ - NCT07848815Recruiting
Lung cancer checks for COPD patients
This study looks at people with COPD to find lung cancer earlier using risk-based checks. It may help catch cancer sooner and guide better care.
Vejle, Region SyddanmarkAges 50 years+ - NCT07844590Recruiting
Early breathing problem detection in ALS
This study tests new ways to find breathing problems early in people with ALS. It uses MRI scans and other checks to see how the disease affects breathing muscles, which could help doctors treat symptoms sooner.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07849491Enrolling by invitation
Pharmacist-led antibiotic review for respiratory infections
This study tests whether a pharmacist-led deprescribing strategy—carefully reviewing and possibly reducing or stopping antibiotics that may not be needed—can improve safety and outcomes in patients with respiratory infections taking azithromycin.
Islamabad, IslamabadAges 18–65 - NCT07843381Recruiting
Testing a new drug for Sjögren's syndrome with lung disease
This clinical trial tests a new drug called telitacicept for people who have both Sjögren's syndrome and interstitial lung disease. The drug aims to reduce the immune system's attack on your body and may help improve lung symptoms.
BeijingAges 18–70 - NCT07846423Recruiting
Rapid flu testing for fever and respiratory illness
This study tests a fast, point-of-care test to detect the flu in adults who have fever and respiratory symptoms. The goal is to see if this quick test can help doctors diagnose and treat flu more effectively.
TaichungAges 20 years+ - NCT07845747Enrolling by invitationPhase 4
Comparing inhaled versus intravenous tranexamic acid for coughing up blood
This study compares two ways of giving tranexamic acid, a medicine that helps blood clot, to stop bleeding in the lungs. One way is through a breathing mist (inhaled), and the other is through a vein (IV). The goal is to see which method works better and is safer for people who are coughing up blood.
Karachi, SindhAges 18–60 - NCT07848243RecruitingPhase 2
A new imaging test to find returning cancer
This trial tests a new imaging agent that helps find cancer cells that have come back. It is given as an injection and then a scan is done to see if it helps doctors locate the cancer.
BeijingAges 18 years+ - NCT07848165Recruiting
Probiotics to prevent pneumonia in children on breathing machines
This trial tests whether giving probiotics (good bacteria) can help prevent pneumonia in children who are on a breathing machine in the intensive care unit. If your child is on a ventilator, these friendly bacteria might help keep their lungs healthy.
Tanta, Al GharbiaAges 1 month–18 years - NCT07845305Enrolling by invitation
Breathing tube placement with sedation only to preserve breathing
This study tests whether giving only sedation (not a paralytic drug) during emergency breathing tube placement can help you keep breathing on your own. It aims to see if this approach is safer and helps recovery.
Nashville, TennesseeAges 18 years+ - NCT06446232Recruiting
Flu vaccine effectiveness in young children
This trial studies how well the flu vaccine works in young children in Taiwan. To join, your child must have a positive flu test and a known vaccination record.
TaipeiAges 6 months–18 years - NCT06445881RecruitingPhase 2
Herbal medicine for lung cancer before and after surgery
This trial is testing whether adding a traditional Chinese herbal formula (Modified Si Jun Zi Tang) to standard treatment before and after surgery can help people with early-stage non-small cell lung cancer. It aims to see if the herbs improve outcomes and reduce side effects.
Hangzhou, ZhejiangAges 18–75 - NCT05284539RecruitingPhase 2
Chemo plus immunotherapy for mutated advanced lung cancer
This trial studies whether combining platinum chemotherapy with immune “checkpoint” medicine works better for people with stage IV lung cancer that has EGFR, ALK, or ROS1 mutations. It focuses on tumors that have grown again after first-line treatment.
Changsha, HunanAges 18 years+ - NCT06362122Recruiting
Severe nasal polyps: links between symptoms, tissue, and blood
This study looks at people with severe nasal polyps that need surgery (ethmoidectomy) for the first time. Researchers want to understand the connection between your symptoms, nasal tissue, and blood tests.
PoitiersAges 18 years+ - NCT06452966Recruiting
Traditional Chinese medicine for organ failure in ICU
This trial is studying whether adding traditional Chinese medicine (TCM) to standard care can help patients in the surgical ICU recover from organ failure. It looks at how TCM might support your body's organs during critical illness.
TaichungAges 20 years+ - NCT04005508Recruiting
Study sleep apnea and heart outcomes in high-risk atrial fibrillation
This trial looks at how obstructive sleep apnea (OSA, a breathing problem during sleep) relates to heart outcomes in people with atrial fibrillation (AF). It may help doctors better predict risk and choose safer care for people who are high cardiovascular risk.
SingaporeAges 22–99 - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT06284577Recruiting
Quality of life and gut health in children with cystic fibrosis
This study looks at how a drug called ETI (a combination of three medicines) affects the quality of life and gut health of children with cystic fibrosis. If you or your child has the right type of CF and is between 2 and 18 years old, this trial may help us understand how treatment improves daily life and digestion.
OsloAges 2–18 - NCT02815683Recruiting
Bronchoscopy treatment with one-way lung valves
This study looks at outcomes from placing one-way valves in the lungs using a camera procedure through the airways (bronchoscopy). If you’re already planned for this type of valve treatment, you may be able to join to help researchers learn how it works.
GroningenAges Any age - NCT04214587Recruiting
Study of removed lung valves after treatment
This study looks at lung tissue taken out after a treatment that places a one-way lung valve to help breathing. They want to learn how the valve affects the airway and lung over time.
GroningenAges Any age - NCT07838519Enrolling by invitation
Personalized lung cancer screening for veterans
This study tests a personalized approach to help veterans decide if lung cancer screening is right for them. It aims to improve early detection by considering each person's unique risk factors, such as smoking history, military exposures, and lung health.
Aurora, ColoradoAges 50–80 - NCT07839949Recruiting
Monitoring breathing effort during ventilator weaning
This study tests a new, non-invasive way to monitor how hard your breathing muscles are working while the ventilator support is being reduced. It aims to help doctors wean you off the ventilator more smoothly and safely.
Palma de Mallorca, Balearic IslandsAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.