Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT02156401Recruiting
Study of tests and care to improve clot diagnosis
This study follows adults who may have a blood clot in the lung (pulmonary embolism) or leg (deep vein thrombosis), or who were found to have a clot by chance. It aims to improve how doctors diagnose, manage, and estimate risk, which may lead to better, more tailored care for you.
Mainz, Rhineland-PalatinateAges 18 years+ - NCT06371482RecruitingPhase 2
Durvalumab plus chemoradiation for limited-stage small cell lung cancer
This trial tests adding the immunotherapy drug durvalumab to standard chemotherapy and radiation for limited-stage small cell lung cancer. The goal is to see if this combination helps control the cancer better than standard treatment alone.
Shijiazhuang, HebeiAges 18–75 - NCT07841288Recruiting
Klebsiella pneumoniae infections in the respiratory ICU
This study looks at how common Klebsiella pneumoniae bacteria are in patients in the respiratory ICU. If you have this infection, the study may help doctors understand how many people get it and how it affects them.
SohagAges 18 years+ - NCT07834346RecruitingPhase 3
Clarithromycin to prevent new infections in sepsis after pneumonia
This study tests whether an antibiotic called clarithromycin can help prevent additional infections in people who have sepsis from pneumonia. The goal is to see if it helps you recover faster and avoid complications.
Pátrai, AchaeaAges 18 years+ - NCT07841691Recruiting
Improving antibiotic use for chest infections in young children
This study looks at how to use antibiotics more effectively for young children with chest infections. It aims to improve treatment and reduce unnecessary antibiotics.
Johannesburg, GautengAges 2 months–2 years - NCT07837375Recruiting
Physical activity support app for COPD patients
This study tests a mobile app that helps people with COPD exercise more safely, possibly by giving them better tips and reminders. It aims to see if the app can improve their daily activity and overall wellbeing.
MontivilliersAges 18 years+ - NCT07841249Recruiting
Recovery of heart and lung fitness after lung surgery
This study compares how well patients recover their heart and lung fitness after two types of lung surgery: removing a whole lobe versus removing a smaller part of the lung. It may help doctors understand which surgery leads to better recovery.
Wuhan, HubeiAges 18 years+ - NCT07835945Recruiting
Testing blood gas from artery vs fingertip in breathing distress
This trial compares blood drawn from an artery (arterial blood gas) with blood from a fingertip (capillary blood gas) to see if the fingertip test gives accurate enough results for patients in the emergency room with breathing problems caused by COPD or heart failure. It might help reduce the pain and discomfort of repeated artery tests.
NiceAges 18 years+ - NCT07837830RecruitingEarly Phase 1
Early treatment for exercise-related lung pressure
This trial tests an inhaled medicine that may help people with lung scarring or connective tissue disease who have high blood pressure in the lungs only during exercise. It aims to improve their ability to be active and reduce symptoms.
Paramus, New JerseyAges 18 years+ - NCT07838298RecruitingPhase 4
Flu vaccine response in older adults who get it yearly
This study checks how well the seasonal flu vaccine works in people 65 and older who have had flu shots regularly. It compares their immune response to that of younger adults to see if repeated vaccination still protects them.
SeoulAges 19 years+ - NCT07837128Recruiting
Gentle breathing support in intensive care
This trial tests two ways of using a breathing machine (ventilator) in the ICU. One method is more gentle on the lungs, and the goal is to see if it helps patients recover faster.
Amsterdam, NLAges 18 years+ - NCT07842133Recruiting
Relaxation exercises for fatigue and breathing in scleroderma
This study tests whether progressive muscle relaxation exercises can help reduce fatigue and shortness of breath while improving lung function in people with scleroderma. Participants will learn and practice these exercises as part of the study.
Gaziantep, ŞehitkamilAges 18–65 - NCT07838025Recruiting
Breathing monitor during lung surgery
This study tests a new monitor (AirGo™) that tracks breathing during surgery to remove part of the lung. It may help doctors watch your breathing more closely and could lead to safer procedures.
Pavia, LombardyAges 21–80 - NCT07841223Recruiting
Nasal oxygen therapy for mouth breathers after surgery
This trial tests a special oxygen mask that fits inside the nose for people who breathe through their mouth after surgery. It may help you get enough oxygen while you recover in the post-anesthesia care unit.
Nanjing, JaingsuAges 18 years+ - NCT07839234Enrolling by invitation
Personalized breathing support for lung injury patients
This trial tests a new way to adjust breathing machine settings for people with a lung condition called ARDS. The adjustments are based on detailed monitoring of the heart and lungs, aiming to improve recovery.
Xiamen, FujianAges 18 years+ - NCT07838051Recruiting
Muscle relaxants for sore throat after breathing tube
This study tests whether giving muscle relaxants during surgery can reduce sore throat after using a special breathing tube called a video laryngeal mask airway. It may help people who are having longer surgeries and have a higher body mass index.
Samsun, SamsunAges 18–70 - NCT07837739Recruiting
EGFR-targeted pill after surgery for early lung cancer
This trial tests whether taking an EGFR-targeted pill after lung cancer surgery can lower the chance of the cancer coming back. It is for people with early-stage non-small cell lung cancer that has a specific EGFR mutation.
Wuhan, HubeiAges 18–75 - NCT05865782Recruiting
Green schoolyard changes to help kids move more
This study looks at whether rebuilding schoolyards with more greenery can increase physical activity for children. It also aims to help with climate-related goals by changing the school environment.
StockholmAges 8–13 - NCT04814407Recruiting
Test blood and other markers to detect early lung cancer
This study looks for new “epigenetic” signals in blood (signals about how genes are turned on/off) to help detect lung cancer early. You might be able to join if you are being evaluated for possible lung cancer or have small, unclear spots on a lung CT scan.
TaipeiAges 20 years+ - NCT04893785RecruitingPhase 2
Cabozantinib plus temozolomide for advanced neuroendocrine lung tumors
This Phase 2 study tests whether combining cabozantinib with temozolomide can control advanced lung or gastrointestinal neuroendocrine tumors that have grown after prior treatments. It also closely monitors safety, including blood counts, organ function, and other side effects.
Naples, CampaniaAges 18 years+ - NCT06464757Recruiting
Laryngomalacia and breathing in children: before and after treatment study
This trial is for children with laryngomalacia (a floppy voice box) who have noisy breathing and trouble breathing. It will check how they are doing before and after treatment, and follow up for one year to see how their quality of life improves.
OsloAges 1 week–12 months - NCT03890224Recruiting
Testing breathing support needs in COPD with high CO2
This trial studies how different breathing support strategies affect people with COPD who have high carbon dioxide (CO2) in their blood. It may help care teams choose safer respiratory support after a breathing machine is stopped.
Paris, Île-de-France RegionAges 18 years+ - NCT06110572RecruitingPhase 1/Phase 2
Total body irradiation with immunotherapy for extensive SCLC
This trial adds total body irradiation (a low dose of radiation to the whole body) to standard atezolizumab (immunotherapy) plus chemotherapy for people with extensive-stage small cell lung cancer. The goal is to see if the radiation helps the immunotherapy work better.
Nashville, TennesseeAges 18 years+ - NCT06467786RecruitingPhase 4
Irinotecan liposomes for advanced small cell lung cancer
This trial is testing a new form of chemotherapy called irinotecan liposomes for people with advanced small cell lung cancer that has worsened after initial treatment. It aims to see if this drug can shrink tumors and improve survival.
Xi'an, ShannxiAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.