Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,346 recruiting studies in this area right now.
By phase
- Not applicable4,049
- Phase 2834
- Phase 1456
- Phase 3421
- Phase 1/Phase 2309
- Phase 4212
- Phase 2/Phase 365
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer184
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1993
- Colorectal Cancer90
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis76
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama178
- Arizona153
- Florida120
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,346 total
- NCT06421805Recruiting
Mediastinal Tumor Patient Database Study
This study is building a database of people with mediastinal tumors. It will collect health information over time to help doctors better understand these tumors and improve care.
Beijing, Beijing MunicipalityAges Any age - NCT06421298RecruitingPhase 2
Tafolecimab and sintilimab plus chemo for advanced lung cancer
This trial is testing a new combination of treatments, including an immune drug (sintilimab) and a cholesterol-lowering drug (tafolecimab), along with chemotherapy, for people with advanced lung cancer that no longer responds to standard immunotherapy.
Beijing, Beijing MunicipalityAges 18–75 - NCT05435794Recruiting
Long-term study of CPAP or a mouth guard for sleep apnea
This trial studies how CPAP (a breathing machine) or a custom mouth guard (MAD) affects sleep over the long term in people with obstructive sleep apnea. It may help confirm which treatment improves sleep and how well it works over time.
AngersAges 18–80 - NCT07852403Recruiting
Sleep problems and outcomes in pulmonary arterial hypertension
This study looks at how sleep-disordered breathing (abnormal breathing during sleep) affects the long-term health of people with pulmonary arterial hypertension (PAH), a type of high blood pressure in the lungs. By participating, you will have a sleep study and be followed over time to see how your breathing during sleep relates to your PAH outcomes.
BeijingAges 18 years+ - NCT07850934Recruiting
Melatonin for high blood pressure in the lungs of newborns
This trial tests whether giving melatonin to full-term newborns with high blood pressure in their lungs (pulmonary hypertension) can help improve their breathing and oxygen levels. It may offer a new treatment option for babies with this condition.
Cairo, AbbassiaAges Any age - NCT07851740Recruiting
Lung surgery breathing settings study
This study tests different breathing settings during lung surgery to see which one helps keep your lungs healthy. It may help you breathe better after surgery.
Barcelona, CataloniaAges 18 years+ - NCT07850908Enrolling by invitation
Ventilation method for newborns with persistent pulmonary hypertension
This study tests a specific type of breathing machine (ventilator) that adjusts air pressure to help newborns with persistent pulmonary hypertension breathe better. It aims to see if this method improves oxygen levels and outcomes for babies needing mechanical ventilation in their first week of life.
Tanta, Gharbia GovernorateAges 1 day–2 months - NCT06423118Recruiting
Sleep apnea and thinking skills in older adults
This study looks at how sleep apnea affects thinking and memory in older adults. If you join, you'll wear comfortable, non-invasive sensors overnight to monitor your sleep and breathing patterns.
Toronto, OntarioAges 55–85 - NCT07851246RecruitingPhase 3
Flu vaccine study for adults 18 to 64
This study tests a new flu vaccine to see how well it protects adults aged 18 to 64. If you join, you'll get the vaccine and have some check-ups to see how your body responds.
Glendale, ArizonaAges 18–64 - NCT07851623RecruitingPhase 1
Inhaled study drug for healthy adults and adults with asthma
This early-phase study tests an inhaled medication (CHF10136) to see if it's safe and how the body handles it. It includes both healthy adults and people with asthma, and participants will be monitored closely throughout.
LeedsAges 18–65 - NCT06425354Recruiting
Can breathing machine energy predict lung inflammation?
This study looks at a new measure called 'mechanical power' (the energy from the breathing machine) to see if it can predict inflammation in the lungs and blood of patients with low oxygen levels. It may help doctors better understand how the breathing machine affects lung damage.
RomaAges 18 years+ - NCT06424899RecruitingPhase 2
Chemoimmunotherapy before and after chemoradiation for stage III lung cancer
This study tests whether combining chemotherapy with immunotherapy before and after chemoradiation helps people with stage III lung cancer that can be removed by surgery. It might improve how well treatment works and reduce the chance of cancer coming back.
Hangzhou, ZhejiangAges 18–75 - NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT05897879Recruiting
Study how pertussis germs and immune response affect severity
This study looks at children with suspected pertussis (who need a PCR test) and compares how the bacteria and the immune response relate to how sick they become. It may help doctors understand why some children have worse symptoms and guide future care.
BordeauxAges Up to 15 years - NCT06429579Recruiting
Potts shunt for severe pulmonary hypertension in children
This trial tests a surgery called a Potts shunt for children with severe pulmonary hypertension (high blood pressure in the lungs). It may help children who are still very sick despite standard medications.
Beijing, Beijing MunicipalityAges 6 months–18 years - NCT05758532RecruitingPhase 4
Modified measles vaccine schedule to help prevent allergies in babies
This study tests whether changing the measles vaccine timing in 6-month-old children can reduce allergy risk and also help protect against unrelated infections. If your child is already up to date with routine vaccines, they may be eligible for a modified measles (MMR) schedule used in the trial.
GenevaAges 6 months–6 months - NCT06256237RecruitingPhase 2
Immunotherapy plus chemo before surgery for limited-stage small cell lung cancer
This trial tests whether adding two immunotherapy drugs (toripalimab and JS004) to standard chemotherapy before surgery can help shrink limited-stage small cell lung cancer. The goal is to find better ways to treat this cancer before surgery.
ShanghaiAges 18 years+ - NCT05630443Recruiting
Prone position after major abdominal cancer surgery
This study looks at whether placing you in a face-down (prone) position after major abdominal cancer surgery can improve recovery. You may be offered this positioning approach after your operation if it’s safe for you.
GothenburgAges Any age - NCT05584267RecruitingPhase 2
Immunotherapy plus targeted brain radiation for lung cancer
This Phase 2 trial studies whether giving immunotherapy along with a precise form of brain radiation can control brain metastases from non-small cell lung cancer. It may help by shrinking or stabilizing spots in the brain while your body’s immune system is also activated.
Changsha, HunanAges 18 years+ - NCT06109558RecruitingPhase 1/Phase 2
LMV-12 plus Osimertinib for advanced lung cancer
This trial tests a new drug called LMV-12 combined with osimertinib for people with advanced non-small cell lung cancer that has certain genetic changes (MET amplification or RET fusion) and has stopped responding to standard EGFR inhibitor treatments.
Changsha, HunanAges 18 years+ - NCT07842510Recruiting
Controlled oxygen for copd flare-ups in the icu
This trial tests whether giving oxygen in a carefully controlled way (using a target range) works better than standard oxygen treatment for people in the ICU with a COPD flare-up. It aims to see if the controlled approach leads to better outcomes, like helping you recover faster.
Mahdia, Mahdia GovernorateAges 40 years+ - NCT07843940RecruitingPhase 1/Phase 2
Two study drugs for extensive-stage small cell lung cancer
This trial tests two new immunotherapy drugs (obrixtamig and pumitamig) given together for people with extensive-stage small cell lung cancer. The goal is to see if the combination is safe and helps shrink or control the cancer.
Miami, FloridaAges 18 years+ - NCT03979170Recruiting
Test lung cancer drug response using patient tumor mini-organs
This trial grows “organoids” (mini tumor models) from your lung cancer tissue to see which drug responses are most likely. It may help match future treatments to how your tumor behaves in the lab.
GenevaAges 18 years+ - NCT06439290Recruiting
Voice Changes After Vocal Cord Surgery
This study looks at how different types of voice surgery affect the voice. Researchers will record and analyze voices before and after surgery to understand the results better.
Ghent, East-FlandersAges 18–70
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,346 recruiting pulmonology studies from the U.S. registry right now, out of 9,900 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.