Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,643 recruiting studies in this area right now.
By phase
- Not applicable4,313
- Phase 2851
- Phase 1471
- Phase 3424
- Phase 1/Phase 2309
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas91
- Pennsylvania82
- Illinois72
Recruiting studies6,643 total
- NCT07362940RecruitingPhase 1/Phase 2
Study of GEN-725 plus Dositinib for advanced EGFR-positive lung cancer
This trial tests a new combination of two drugs (GEN-725 and Dositinib) for people with advanced non-small cell lung cancer that has a specific genetic change called an EGFR mutation. It aims to see if this combination can help when standard treatments stop working or as a first treatment.
BeijingAges 18–75 - NCT07363304Recruiting
How ETI therapy affects body and gut in cystic fibrosis
This study looks at how the triple combination therapy (elexacaftor/tezacaftor/ivacaftor, or ETI) affects your body's metabolism, epigenetics, and gut bacteria in people with cystic fibrosis. It aims to understand the broader health benefits of this treatment.
Bari, BariAges 2 years+ - NCT07363811Recruiting
Nivolumab and immune cells in advanced lung cancer
This trial looks at the level of a specific type of immune cell (large granular lymphocytes) in people with advanced non-small cell lung cancer that has spread. It aims to see if these cells affect how well the drug nivolumab works. This could help doctors understand which patients benefit most from treatment.
Konya, MeramAges 18–90 - NCT07364318Recruiting
Thinking and memory in sleep apnea
This study looks at how thinking and memory are affected in people with newly diagnosed obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to understand the impact of sleep apnea on brain function.
BratislavaAges 18–65 - NCT07365137Recruiting
Study of choking rescue methods in Alberta
This study watches people who choked on something (like food) and got help while they were awake. It aims to learn which first aid methods work best for adults and children over age 2.
Calgary, AlbertaAges 3 years+ - NCT07366593Recruiting
Immune & respiratory health in Down syndrome kids with pneumonia
This study looks at how the immune system and breathing are affected in children with Down syndrome who have pneumonia. It aims to find patterns that could lead to better treatments.
CairoAges 1–6 - NCT07366879Recruiting
Exercise program for newly diagnosed pulmonary hypertension
This study tests whether a home-based exercise program, added to your regular medications, can help people who are newly diagnosed with pulmonary arterial hypertension feel better and improve their daily function.
GlasgowAges 18 years+ - NCT07367022Recruiting
Sleep monitors for children with autism
This study tests whether a portable sleep monitor works well for children with autism who are having their first sleep study. It aims to find easier ways to track sleep patterns at home.
Vancouver, British ColumbiaAges 6–18 - NCT07367581Recruiting
Comparing two nerve blocks for lung surgery pain
This study compares two types of numbing blocks to manage pain after lung cancer surgery. If you qualify, you'll receive one of these blocks to see which provides better pain relief.
CairoAges 18–65 - NCT07369752Recruiting
Breathing exercises for teens with depression or anxiety
This study looks at whether breathing exercises can help improve brain health and mental well-being in teens with depression or anxiety. It is designed for adolescents who are already receiving care at a Mayo Clinic psychiatry clinic.
Albert Lea, MinnesotaAges 12–17 - NCT07370077Recruiting
Early screening for lung nodules with breath, blood, and CT scans
This trial uses a new, non-invasive way to screen for lung cancer by combining your breath, blood, and CT scan images. The goal is to figure out whether a nodule found on a CT scan is cancerous or not, which could help patients avoid unnecessary procedures.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07370350Recruiting
Ultrasound study of tongue in children with obesity
This study uses ultrasound (a safe, painless scan) to look at the tongue and how it moves in children and teenagers with obesity. Researchers want to learn more about tongue features that might affect breathing or weight, and the results could help improve care.
BrusselsAges 6–18 - NCT07371182Recruiting
Luvometinib for children with LCH in certain bone sites
This trial tests the drug luvometinib for children with a specific type of bone disease called Langerhans cell histiocytosis (LCH). It may help kids who have not been treated before and whose LCH is in certain bones, including the head, face, or spine.
Hefei, AnhuiAges birth–18 years - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07372794Recruiting
Lung imaging-guided breathing therapy for patients on ventilators for weeks
This study tests whether using a special lung imaging technique called EIT can help guide breathing exercises and physical therapy for people who have been on a breathing machine for 21 days or more. The goal is to see if this approach helps your lungs work better and speeds up recovery.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07372989RecruitingPhase 1
Inhaled amniotic fluid for lung scarring
This trial tests whether breathing in a mist of human amniotic fluid can help people with interstitial lung disease, a condition where lung tissue becomes scarred and stiff. It aims to see if this treatment is safe and might improve your breathing.
Venice, FloridaAges 18 years+ - NCT07373288Recruiting
HOXB7 and lung markers in pulmonary fibrosis
This study looks at a protein called HOXB7 and other markers in lung tissue and blood to better understand pulmonary fibrosis. It may help researchers find new ways to diagnose or treat the disease.
ModenaAges 18–80 - NCT07373964RecruitingPhase 2
Study of new drug combo for extensive-stage small-cell lung cancer
This trial tests a new combination of drugs (chidamide, a PD-L1 inhibitor, carboplatin, and etoposide) as the first treatment for people with extensive-stage small-cell lung cancer. The goal is to see if this combination works better than standard treatments.
Shenyang, LiaoningAges 18–75 - NCT07374562Recruiting
Nerve block for Long COVID symptoms
This study tests a nerve block injection (called a stellate ganglion block) to see if it can help relieve ongoing symptoms of Long COVID, especially breathing problems. It is for people who have had COVID-19 symptoms for at least 3 months.
Trois-Rivières, QuebecAges 18 years+ - NCT07374614Recruiting
Study of iruplinalkib after lorlatinib for ALK-positive lung cancer
This trial is for people with advanced lung cancer whose tumors have an ALK gene change and who have already taken a medicine called lorlatinib. It tests a new drug, iruplinalkib, to see how well it works for those who stopped responding to or couldn't tolerate lorlatinib.
Shenzhen, GuangdongAges 18 years+ - NCT07375316RecruitingPhase 2
Combination therapy for EGFR-mutated lung cancer with lingering ctDNA
This trial tests if adding sacituzumab tirumotecan to osimertinib works better than osimertinib alone for advanced lung cancer that still shows cancer DNA (ctDNA) in the blood after initial osimertinib treatment.
Guangzhou, GuangdongAges 18 years+ - NCT07375433Recruiting
Heart failure and COPD study for patients aged 50 to 70
This trial looks at how heart failure with preserved pumping function affects people who also have COPD. It aims to understand the course of the disease and long-term outlook.
Kazan'Ages 50–70 - NCT07375667Recruiting
Airway suction guidance in ventilated patients
This trial uses dynamic airway resistance and machine learning to guide when sputum suction is needed in ventilated patients with ARDS, AECOPD, or severe pneumonia.
Bengbu, AnhuiAges 18–90 - NCT07376343Recruiting
Comparing CPAP pressure formulas vs lab titration for sleep apnea
This study compares two ways to set CPAP machine pressure for Thai people with obstructive sleep apnea: using a quick formula versus a full overnight lab test. It helps find the best pressure more easily.
Pathum ThaniAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,643 recruiting pulmonology studies from the U.S. registry right now, out of 10,656 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.