Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,644 recruiting studies in this area right now.
By phase
- Not applicable4,309
- Phase 2852
- Phase 1471
- Phase 3427
- Phase 1/Phase 2310
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer426
- Asthma194
- Non Small Cell Lung Cancer188
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama172
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas91
- Pennsylvania81
- Illinois72
Recruiting studies6,644 total
- NCT07009535Enrolling by invitation
Sleep apnea risk and orthodontic issues in children
This study looks at how narrow upper jaws (maxillary constriction) relate to sleep apnea in children with mixed teeth. It aims to understand if dental problems affect breathing during sleep and guide future treatments.
Pavia, LombardyAges 6–12 - NCT06997458Enrolling by invitation
Liquid biopsy study for advanced lung or colon cancer
This study is testing a simple blood draw (liquid biopsy) to track advanced lung or colon cancer. It may help doctors understand the cancer better without needing repeated tissue biopsies.
Granada, AndalusiaAges 18 years+ - NCT06986343Enrolling by invitation
Palatal expansion and activator device for sleep in children
This trial tests if a palatal expander combined with an Up-Locker activator can improve sleep and open up the airway in children with sleep-disordered breathing. It may help kids who snore and have a narrow upper jaw.
Medellín, AntioquiaAges 6–8 - NCT06976762Enrolling by invitation
Light-based muscle oxygen measurements in COPD with kidney disease
This study uses a special light-based device (near-infrared spectroscopy) to measure muscle oxygen levels in people who have both COPD and chronic kidney disease. Researchers want to see if these measurements can help predict how the disease progresses, which could lead to better monitoring and treatment.
Tokat ProvinceAges 18–80 - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06966817Enrolling by invitation
Mouth care solutions for ventilator patients in the ICU
This study tests two different mouth-care solutions for patients on breathing machines, to see if they can prevent pneumonia and improve mouth health in intensive care.
AnkaraAges 18–90 - NCT06963190Enrolling by invitation
Breathing Muscle Training After Lung Transplant
This study tests two types of breathing muscle training exercises in people who have had a lung transplant. The goal is to see which type helps you breathe better and improves your daily living.
Santander, CantabriaAges 18 years+ - NCT06962449Enrolling by invitation
Study of Tislelizumab as First Treatment for Advanced Lung Cancer
This study looks at how well Tislelizumab works as the first treatment for advanced non-small cell lung cancer that has spread. It aims to understand which treatment strategies after Tislelizumab lead to the best survival outcomes for patients.
Shanghai, Shanghai MunicipalityAges Any age - NCT06958042Enrolling by invitation
Lung and bladder health study for COPD patients
This study looks at how common bladder problems are in people with stable COPD. It aims to help doctors better understand and manage these symptoms.
Kütahya, CenterAges 40–65 - NCT06943989Enrolling by invitation
Breathing ozone vs. clean air at rest
This study tests how resting healthy adults respond to breathing low levels of ozone (a common air pollutant) compared to clean air. Researchers will measure lung function and signs of inflammation in your blood or breath.
Chapel Hill, North CarolinaAges 18–35 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06931886Enrolling by invitation
Breathing training for pulmonary hypertension
This trial tests if special breathing exercises can help people with pulmonary hypertension. You may join if your condition is stable and you haven't smoked in the last 10 years.
Tucson, ArizonaAges 18 years+ - NCT06931782Enrolling by invitation
AI for respiratory disease screening study
This trial tests whether an artificial intelligence (AI) tool can help prevent, diagnose, and triage respiratory diseases. It is open to adults without medical training who can follow a survey.
Guangzhou, GuangdongAges 18–75 - NCT06920407Enrolling by invitation
BreatheWell: Breathing and relaxation for health
This research study tests a simple breathing and relaxation program called BreatheWell. If you are a generally healthy adult who isn't taking certain medications or using fitness trackers, you may be able to join and learn techniques to calm your body and mind.
Los Angeles, CaliforniaAges 18 years+ - NCT06916598Enrolling by invitation
Defining lung complications after surgery
This study aims to create a clear, agreed-upon definition for lung problems after surgery. It's not a treatment trial but a way to help doctors and patients better identify and grade these complications.
Wolverhampton, WolverhamptonAges 18 years+ - NCT06916104Enrolling by invitation
Allergies and biotherapy in severe asthma
This study looks at whether having a respiratory allergy affects how well biotherapy works for people with severe asthma. It includes adults already on biotherapy and followed at Poitiers University Hospital.
PoitiersAges 18 years+ - NCT06915077Enrolling by invitation
Personalized treatment for sleep apnea
This study tests alternative treatments for people with moderate to severe sleep apnea who cannot use CPAP. It aims to find more tolerable options.
Wilrijk, AntwerpenAges 18 years+ - NCT06912945Enrolling by invitation
Laser vs. standard tools for benign voice box growths
This study compares using two types of diode laser (980 nm and 450 nm) to traditional cold instruments for removing non-cancerous growths on the voice box. The goal is to see which approach works better based on the type of growth, patient factors, and laser settings.
Sohag, Sohag GovernorateAges Any age - NCT06910800Enrolling by invitation
Self-management for patients with a chest tube
This study gathers feedback from patients and caregivers about living with an indwelling pleural catheter (a tube that drains fluid from the chest). Your input will help design a 'self-management' program so patients can feel more in control at home.
Norwich, NorfolkAges 18 years+ - NCT06902792Enrolling by invitationPhase 1
Adebrelimab and trametinib for children with hard-to-treat LCH
This trial tests a combination of two drugs for children and teens with Langerhans cell histiocytosis (LCH) that has not responded to standard treatments or has come back after treatment. The goal is to see if the drugs can shrink lesions and improve symptoms.
Wenzhou, ZhejiangAges Up to 18 years - NCT06892236Enrolling by invitation
Creating gene-corrected stem cells for Alpha-1 Antitrypsin Deficiency
This trial uses your own cells to create stem cells (iPSCs) that can be genetically corrected to treat severe Alpha-1 Antitrypsin Deficiency. It is an early study exploring a potential cure.
Pavia, PaviaAges 18 years+ - NCT06885515Enrolling by invitation
Telomere length in Israeli patients with fibrotic ILD
This study looks at the length of telomeres (a part of your DNA) in people with fibrotic interstitial lung disease (ILD) in Israel. It aims to understand how telomere length relates to this condition and may help guide future care.
AshkelonAges 18 years+ - NCT06885424Enrolling by invitation
Long-term follow-up for A2 Bio gene therapy patients
This study follows up with people who previously received a gene therapy product from A2 Biotherapeutics in an earlier trial. The goal is to monitor their health over time and check for any long-term effects.
Gilbert, ArizonaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,644 recruiting pulmonology studies from the U.S. registry right now, out of 10,689 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.