Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,644 recruiting studies in this area right now.
By phase
- Not applicable4,309
- Phase 2852
- Phase 1471
- Phase 3427
- Phase 1/Phase 2310
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer426
- Asthma194
- Non Small Cell Lung Cancer188
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama172
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas91
- Pennsylvania81
- Illinois72
Recruiting studies6,644 total
- NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Birmingham, AlabamaAges 6 years+ - NCT06257420Enrolling by invitation
Low-dose rapamycin for ME/CFS and Long-COVID
This trial tests whether a low dose of rapamycin, a drug that may help regulate the immune system, can improve symptoms in people with ME/CFS or Long-COVID.
Palo Alto, CaliforniaAges 18–65 - NCT06250777Enrolling by invitationPhase 2
T-DXd for HER2-mutant lung cancer with brain metastases
This trial tests a drug called T-DXd in people with advanced non-squamous lung cancer that has a specific HER2 gene change (mutation) and has spread to the brain but isn't causing symptoms. The goal is to see if the drug can shrink tumors and help control the cancer.
SeoulAges 20 years+ - NCT06236685Enrolling by invitation
Optimizing ventilation monitoring with advanced techniques
This trial tests a new way to monitor breathing for people on a ventilator during surgery or in intensive care. It aims to improve care by combining advanced monitoring methods.
PragueAges 18 years+ - NCT06164639Enrolling by invitation
Biomarkers and causes of lung injury from reflux
This study looks at why some people on breathing tubes develop lung damage from stomach acid getting into the lungs. It may help find better ways to prevent or treat this injury.
ShanghaiAges 18–99 - NCT06147453Enrolling by invitation
Oscillating positive expiratory pressure therapy for mucus in asthma
This trial tests a device that uses vibrations to help clear mucus from your lungs. It may improve airflow and mucus buildup in people with moderate to severe asthma.
Hamilton, OntarioAges 18 years+ - NCT06133530Enrolling by invitation
Human milk sugars for gut health in Antarctica
This study tests whether natural sugars found in human milk (called HMOs) can improve gut health and the immune system. Researchers are looking for healthy adults who are willing to travel to Antarctica for the study.
ErfurtAges 18–65 - NCT06132048Recruiting
Testing a smartphone app for cystic fibrosis
This study tests a smartphone app called MuCopilot that helps you track your cystic fibrosis symptoms at home. Researchers want to see if the app is easy to use and can give accurate information about your condition.
RouenAges 18 years+ - NCT06106204Enrolling by invitation
Reducing antibiotic use after hospital discharge
This study looks at ways to reduce unnecessary antibiotic use when patients are discharged from the hospital after being treated for a UTI or pneumonia. It aims to help you avoid taking antibiotics longer than needed.
Salt Lake City, UtahAges 18 years+ - NCT06041906Enrolling by invitation
International registry for congenital portosystemic shunt
This registry is gathering information from people who have a rare liver blood vessel problem they were born with (congenital portosystemic shunt). By joining, you help researchers learn more about this condition and improve future care.
New Haven, ConnecticutAges 1 day+ - NCT06028412Enrolling by invitation
Lobectomy vs. Sublobar Resection for Small NSCLC
This trial compares two types of lung surgery for early-stage non-small cell lung cancer. You may qualify if you have a small tumor (2 cm or less) with specific features on a CT scan. The goal is to see which surgery offers better outcomes.
Xi'an, ShannxiAges 18–75 - NCT05952999Enrolling by invitation
Studying Hospital-At-Home care done from home
This trial looks at how well a “Hospital at Home” program works when people start from the emergency department or are already in the hospital and can be cared for at home. It may help teams improve care at home for certain medical conditions and situations.
Peoria, IllinoisAges 18 years+ - NCT05942859Enrolling by invitation
AI study using heart ECGs to spot pulmonary hypertension
This study looks at patterns on a 12-lead ECG (a common heart tracing) to help diagnose pulmonary hypertension, using results from a right heart catheter test. It may help doctors use ECGs better in the future, without changing your current care.
BathAges 18 years+ - NCT05925075Enrolling by invitation
Lung ultrasound check for breathing problems in very premature babies
This trial tests whether doing a bedside lung ultrasound can help doctors assess and manage breathing problems in very premature infants. It may help guide care decisions for infants who are struggling to breathe, especially those needing breathing support.
Phoenix, ArizonaAges birth+ - NCT05851755Enrolling by invitation
Italian lung cancer study observing care and outcomes
This is an observational study of people with lung cancer. The goal is to better understand care patterns and outcomes; joining would involve giving consent and answering study questions.
L’AquilaAges 18 years+ - NCT05844449Enrolling by invitationPhase 3
Check long-term safety and effectiveness of CF medicines
This Phase 3 study looks at how well and how safely Vanzacaftor/Tezacaftor/Deutivacaftor works over the long term in people with cystic fibrosis who already took the study medicine before. It may help confirm the best long-term plan and spot important safety issues.
Orange, CaliforniaAges 1 year+ - NCT05831839Enrolling by invitation
Computer training for attention and memory after COVID
This study tests whether computer-based exercises can improve attention and working memory in adults who still have cognitive (thinking) complaints after COVID. It may help if your focus and memory issues have lasted for a while.
Rotterdam, South HollandAges 18 years+ - NCT05787418Enrolling by invitationPhase 3
Nasal spray to prevent COVID-19 after a close exposure
This Phase 3 trial tests whether a medicated nasal spray can stop COVID-19 from starting after you’ve been exposed to someone who recently tested positive. You must start very soon after the person became symptomatic, and you’ll be checked for eligibility based on timing and your health history.
BeijingAges 12–85 - NCT05769023Enrolling by invitation
Pilot test targeting HIV prevention for people who inject drugs
This pilot program studies where HIV risk is highest and uses that information to decide how prevention efforts should be delivered. If you’ve used opioids recently and you inject drugs, you may be invited to participate to help reduce HIV risk.
Baltimore, MarylandAges 18 years+ - NCT05727852Enrolling by invitation
Breath and heart tests to study lung disease stiffness
This study uses breath analysis and heart/electrical heart testing to look at how stiff the arteries are in people with long-term lung conditions. It may help researchers better understand lung disease effects on the cardiovascular system.
MoscowAges 18 years+ - NCT05686837Enrolling by invitation
Study of how lung bacteria spreads in people with cystic fibrosis
This trial follows people with cystic fibrosis to better understand how “nontuberculous mycobacteria” (a type of lung germ) spreads between healthcare visits and care settings. It may help improve future prevention and monitoring strategies for CF patients who have had these bacteria.
Denver, ColoradoAges 1 month–99 years - NCT05632120Enrolling by invitation
Testing how COPD affects daily movement and participation
This study looks at how chronic obstructive pulmonary disease (COPD) may affect your body function, walking, and ability to take part in everyday life. It may help researchers understand what support or therapies could improve daily activities.
Istanbul, Fatih/İstanbulAges 35–80 - NCT05606991Enrolling by invitation
Testing how CPAP affects brain waste clearance during sleep
This study looks at how stopping CPAP for 14 nights affects “brain waste clearance,” a process your brain uses to clear byproducts during sleep. It is testing whether using CPAP versus stopping it changes this brain cleanup in adults with severe obstructive sleep apnea (OSA).
Macquarie Park, New South WalesAges 35–65 - NCT05600933Enrolling by invitation
Providing tumor samples to find new treatment targets
This study collects tumor tissue and related blood tests from people who already need a biopsy or surgery as part of their usual care. Researchers use the samples to learn what drives the tumor and how the tumor environment may affect treatment, which could help develop future therapies.
Bethesda, MarylandAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,644 recruiting pulmonology studies from the U.S. registry right now, out of 10,689 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.