Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,644 recruiting studies in this area right now.
By phase
- Not applicable4,309
- Phase 2852
- Phase 1471
- Phase 3427
- Phase 1/Phase 2310
- Phase 4209
- Phase 2/Phase 366
Top conditions
- Lung Cancer426
- Asthma194
- Non Small Cell Lung Cancer188
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD142
- Breast Cancer111
- COVID-19107
- Pulmonary Hypertension101
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Interstitial Lung Disease79
- Pneumonia79
- Cystic Fibrosis78
- Chronic Obstructive Pulmonary Disease (COPD)73
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama172
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas91
- Pennsylvania81
- Illinois72
Recruiting studies6,644 total
- NCT05589376Enrolling by invitation
Healthy people registry study for you and me
This study sets up a registry of healthy people who can answer surveys and assessments. It helps researchers understand health and how people feel over time, even if you’re not being treated for a specific illness.
Merced, CaliforniaAges 2 years+ - NCT05531630Enrolling by invitation
Xylitol versus saline rinses for sinus symptoms in adults with CF
This study compares two kinds of nasal rinse packets—xylitol versus plain saline—to see which better reduces sinus symptoms. It may help adults with cystic fibrosis and long-term sinus inflammation feel better with routine, at-home nasal care.
LeuvenAges 18 years+ - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+ - NCT05443321Enrolling by invitation
Health information sharing during hospital transfers
This trial studies whether sharing patients’ health information between hospitals during transfers can improve outcomes. You may be included if you are moved from a specific partner hospital to Brigham and Women’s Hospital and admitted to certain hospital units.
Boston, MassachusettsAges 18 years+ - NCT05369611Enrolling by invitation
Share your COVID-19 experiences in a long-term study
This study asks people already enrolled in the NIEHS SELF cohort to answer a questionnaire about their COVID-19 experiences. Your answers can help researchers understand how COVID-19 affected people in this group.
Bethesda, MarylandAges 23–35 - NCT05350774Enrolling by invitationPhase 2
IV immunotherapy for lingering neurologic effects after COVID-19
This Phase 2 trial tests whether intravenous immunotherapy (IVIG) can improve ongoing neurologic symptoms after a mild-to-moderate COVID-19 illness. It targets people with persistent symptoms such as brain fog, fatigue, trouble thinking, dizziness when standing, and balance or other neurologic problems.
Bethesda, MarylandAges 18–100 - NCT05339048Enrolling by invitation
Study of adults from Colombia’s Caribbean coast
This study follows adults who were born or are from Colombia’s Caribbean coast. The goal is to learn about health patterns in this community, but you would not be able to join if you meet certain medical or disability-related criteria.
Cartagena, Departamento de BolívarAges 18–80 - NCT05322785Enrolling by invitation
Breathing sample study to improve exhaled biomarker testing
This study works on better ways to collect and analyze substances from your breath. It may help researchers test how well these “breath markers” reflect lung or whole-body inflammation.
Indianapolis, IndianaAges 4–110 - NCT05285878Enrolling by invitationPhase 2
Fingolimod to protect kidney function after kidney transplant
This trial tests whether fingolimod can reduce kidney scarring and preserve kidney function after a new kidney transplant. It focuses on people who are in the early period after transplant who may be at risk for scarring in the kidney.
Houston, TexasAges 18–65 - NCT05212103Enrolling by invitation
PET scan study for specific cancers using a new tracer
This study uses a PET scan with a special radioactive tracer (68Ga-DOTA-Siglec-9) to look at cancer in certain people. It may help doctors better see cancer-related activity and guide treatment planning for selected cancers.
TurkuAges 18–100 - NCT05131594Enrolling by invitation
Study immune response in Long COVID patients
This trial studies how your immune system responds in people with Long COVID after a past COVID-19 infection. It may help researchers understand why symptoms linger and how the body’s response could be targeted.
Pasadena, CaliforniaAges 18 years+ - NCT05026645Enrolling by invitation
After a chemical, biological, or nuclear disaster exposure
This trial studies how patients are medically managed after being exposed to a chemical, biological, radiological, or nuclear (CBRNE) attack. It may help improve care for people who are treated after these rare disasters, using real medical information recorded by hospital staff.
College Park, MarylandAges Any age - NCT05011071Enrolling by invitation
Alberta BLOOM study for very premature newborns
This study follows babies born very early and their parents to learn about early health and development. It may help doctors better understand what babies need after a premature birth.
Calgary, AlbertaAges birth+ - NCT05001009Enrolling by invitation
Goals of care conversation support for certain serious illnesses
This study helps primary care clinicians and their patients have structured “goals of care” conversations (about what matters most and care preferences). It may help you get clearer, earlier planning—especially if you have a serious illness and higher risk of hospitalization or death.
Palo Alto, CaliforniaAges 18 years+ - NCT04987840Enrolling by invitation
Hospital program to reduce unnecessary lung culture tests in kids
This trial studies a hospital quality-improvement program that aims to use fewer “respiratory culture” tests in pediatric intensive care units (PICUs). It may help reduce unnecessary testing while maintaining good care for critically ill children.
Baltimore, MarylandAges Any age - NCT04954625Enrolling by invitation
Blood patch treatment for leaking air after lung surgery
This study looks at whether an “autologous blood patch” (using your own blood) can help stop an air leak after certain lung operations. It’s designed for adults who still have an air leak on the morning of the third day after surgery.
Chicago, IllinoisAges 18 years+ - NCT04945317Enrolling by invitation
ROSE to improve lung cancer marker testing with a breathing scope
This trial studies a quick scan method (called ROSE) during bronchoscopy to help doctors get the right lung cancer tissue and test cancer markers more accurately. If you are being evaluated for non-small cell lung cancer, the study may improve how well and how fast your samples can be tested.
Chicago, IllinoisAges 18 years+ - NCT04930289Enrolling by invitation
Lung transplant registry for better donor lung preservation
This study builds a worldwide database to track and improve how donor lungs are preserved before transplant. Your information may help doctors choose and manage donor lungs more effectively.
Phoenix, ArizonaAges Any age - NCT04905238Enrolling by invitation
Sleep apnea study linking breathing markers to memory changes
This trial looks at how severe sleep apnea breathing patterns relate to body “biomarkers” linked to Alzheimer’s disease, using blood or other measures. It may help researchers understand whether sleep apnea is connected to memory and brain health—and who might benefit most from better sleep care.
Palma, Balearic IslandsAges 18–65 - NCT04896138Enrolling by invitation
Natural history study for lung scarring patients
This study follows people who are being seen for lung scarring (also called ILD) and compares them with family members without lung scarring. It helps researchers better understand how this condition changes over time and what to look for in the future.
Charlottesville, VirginiaAges 18 years+ - NCT04762459Enrolling by invitationPhase 3
Almonertinib after lung tumor surgery, with or without chemo
This study tests whether almonertinib taken after complete surgery can improve outcomes for people with stage II–IIIA non-small cell lung cancer (NSCLC) that has certain EGFR gene changes. It also compares almonertinib plus chemotherapy versus almonertinib alone to see which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–130 - NCT04579211Enrolling by invitation
Urine testing to skip repeated NTM sputum checks in cystic fibrosis
This study looks at whether a urine test (instead of repeated sputum—mucus—from the lungs testing) can help determine who with cystic fibrosis does not have certain lung germs called NTM. If the urine test works, it could reduce the need for lung sample testing while still keeping people safe.
Denver, ColoradoAges 18 years+ - NCT04534413Enrolling by invitation
Test lung cancer samples outside the body during surgery
This study looks at lung cancer tissue after surgery, using lab testing done outside the body. It may help researchers better observe and study lung tumors using samples taken during lobectomy or segment removal.
Toronto, OntarioAges 18 years+ - NCT04444778Enrolling by invitation
Study intermittent low oxygen in sleep apnea
This study looks at how repeated episodes of low oxygen during sleep affect the body in people with severe sleep apnea. It may help researchers understand what causes symptoms and long-term risks, which could guide better treatment decisions.
Palma, Balearic IslandsAges 18–65
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,644 recruiting pulmonology studies from the U.S. registry right now, out of 10,689 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.