Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07039656RecruitingPhase 2
Toripalimab plus chemo after NSCLC surgery
This trial tests adding the immunotherapy drug toripalimab to chemotherapy after surgery for non-small cell lung cancer (NSCLC). It is for patients who either had no treatment before surgery or had chemo-immunotherapy before surgery and still have signs of cancer in their lymph nodes. The goal is to see if this combination helps prevent cancer from coming back.
Guangzhou, GuangdongAges 18–75 - NCT06444971Recruiting
Muscle relaxation for better lung function in smokers
This study tests a simple muscle relaxation technique to see if it improves how well your lungs work and how easily you breathe. If you are a smoker, this may help you understand more about your lung health.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06243146Recruiting
Oxygen adjustment to prevent lung problems after surgery
This study is testing whether adjusting the amount of oxygen given during and after surgery can help reduce lung complications in people having lung surgery with a special breathing tube. The goal is to find a safer oxygen level that might keep your lungs healthier.
Chengdu, SichuanAges 18–80 - NCT03564236Recruiting
Nasal high-flow oxygen for COPD flare-ups in hospital
This trial tests whether a special type of oxygen delivered through the nose (high-flow nasal oxygen) helps people hospitalized for a COPD flare-up. It is likely meant for people with significant breathing problems and recent repeat flare-ups.
ArnhemAges Any age - NCT06881056Recruiting
Aerosol interferon for RSV pneumonia in toddlers
This study tests an inhaled form of peginterferon alpha-2b for children aged 1 to 3 years who have pneumonia caused by RSV. The goal is to see if this treatment helps them recover faster.
Chengdu, SichuanAges 1–3 - NCT05821933RecruitingPhase 1/Phase 2
Study adds RC108 to targeted EGFR drugs for lung cancer
This Phase 1/2 study tests a new drug (RC108) combined with furmonertinib, with or without an immune drug (toripalimab), in people with EGFR-mutated lung cancer that has gotten worse after prior EGFR treatment. It aims to see how safe the treatment is and whether it can shrink tumors or help control the disease.
Beijing, Beijing MunicipalityAges 18–75 - NCT06378892RecruitingPhase 2
Study of chemo plus lorlatinib for ALK+ lung cancer
This trial tests combining chemotherapy with lorlatinib for people with ALK-positive lung cancer that has spread outside the brain while on lorlatinib. The goal is to see if adding chemo can help control the cancer when it starts growing again.
AvianoAges 18 years+ - NCT06249568Recruiting
Testing fluid response during heart bypass surgery
This study tests a method to see if your body needs more fluids during heart bypass surgery. After the surgeon opens your chest, they will use a special breathing maneuver to check how well your heart responds to extra fluid, which may help guide your care.
AnkaraAges 18–80 - NCT07414472Recruiting
Can breathing tube leak predict stridor in children?
This study monitors air leaks around a child's breathing tube to see if it can help predict stridor (noisy breathing) after the tube is removed. If you have a child aged 0–16 who has been on a breathing tube for at least 6 hours, they may be eligible.
Antwerp, AntwerpAges Up to 16 years - NCT07697183Enrolling by invitationPhase 1
PET scan study for pulmonary arterial hypertension
This study uses a special PET scan tracer (XBD173) to look at inflammation in the lungs of people with pulmonary arterial hypertension (PAH). It aims to understand the role of a protein called TSPO in PAH and may help guide future treatments.
LondonAges 18–75 - NCT07004946Recruiting
New microscope probe for lung lesion diagnosis
This study tests a new microscope probe called CelTouch that doctors can use during a lung biopsy to see cells in real time, which may help diagnose lung lesions more accurately.
Guangzhou, GuangdongAges 18–80 - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT06282718Recruiting
Observational study of respiratory infections in primary care
This study tracks how patients with respiratory infections (like bronchitis, sore throats, or COVID-19) are treated in family doctor offices across Europe. The goal is to learn more about these infections and improve care. You may be able to join if you have a cough, sore throat, or other symptoms that suggest a respiratory infection, and you go to a participating clinic.
AntwerpAges Any age - NCT07295938RecruitingPhase 2
Traditional Chinese medicine as an add-on treatment for mycobacterium abscessus in the lungs
This study tests if adding traditional Chinese medicine to standard treatment helps people with a lung infection called Mycobacterium abscessus. It may improve recovery and reduce side effects.
BeijingAges 18–75 - NCT06262620Recruiting
Comparing biopsy methods for chest lymph nodes
This study compares three different ways to take a tissue sample from swollen lymph nodes in the chest during a bronchoscopy. The goal is to find which method is best at diagnosing the cause of the swelling.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06084117Recruiting
High-flow nasal oxygen for COPD flare-ups
This study tests whether high-flow nasal oxygen (a gentle breathing support through the nose) can help people with a severe COPD flare-up. If you have high carbon dioxide and slightly acidic blood, this treatment might improve your breathing and avoid the need for a breathing tube.
DelftAges 40 years+ - NCT05630443Recruiting
Prone position after major abdominal cancer surgery
This study looks at whether placing you in a face-down (prone) position after major abdominal cancer surgery can improve recovery. You may be offered this positioning approach after your operation if it’s safe for you.
GothenburgAges Any age - NCT06090838Recruiting
Balloon angioplasty for blood clots in the lungs after pulmonary embolism
This trial tests whether balloon angioplasty can improve breathing and exercise ability in people who still have symptoms and blood flow problems 3 months or more after a pulmonary embolism. It is for those who have completed a pulmonary rehabilitation program.
Amsterdam, North HollandAges 18–80 - NCT07631624Recruiting
Blood test for lung cancer screening in smokers and former smokers
This study tests whether a simple blood test that detects smoking-related changes in DNA can help identify who should get lung cancer screening. Researchers want to see if this test is better at finding people at risk than current methods.
Antwerp, AntwerpenAges 50 years+ - NCT07626489Recruiting
Numbing injection to reduce pain after lung surgery
This trial tests whether injecting a numbing medication (ropivacaine) mixed with a steroid (Diprospan) into the surgical area before chest surgery can reduce pain after the procedure. If it works, patients may need fewer pain pills and feel more comfortable during recovery.
Beijing, Beijing MunicipalityAges 18–64 - NCT03681275RecruitingPhase 2
Prevent diaphragm weakness after esophagus surgery
This trial studies a medicine that blocks Janus kinase (JAK) signals, to help prevent breathing muscle weakness in the diaphragm after esophagus removal surgery. It may help patients who need a ventilator during recovery avoid “ventilator-induced” diaphragm dysfunction.
Stanford, CaliforniaAges 18 years+ - NCT06239844Recruiting
Asthma guidance for non-English speaking families
This study helps families who speak a language other than English manage their child's asthma better. It connects you with a guide who supports your family in navigating asthma care and improving your child's breathing.
Aurora, ColoradoAges 4–89 - NCT05311072Recruiting
Update a CTEPH patient database in China
This study helps doctors update and improve how they understand chronic thromboembolic pulmonary hypertension (CTEPH) in patients in China. It likely involves sharing your medical information (not a new drug) and confirming your diagnosis details to support future research.
BeijingAges 14 years+ - NCT07402551RecruitingPhase 2
Testing RC1416 injection for COPD flare-ups
This trial tests an injection called RC1416 for people with moderate-to-severe COPD who still have flare-ups despite using triple inhaler therapy. It may help reduce those flare-ups and improve breathing.
Hefei, AnhuiAges 40–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.