Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06145763Recruiting
Quit smoking with a digital program for American Indian and Alaska Native adults
This study tests two smartphone apps to help American Indian and Alaska Native adults quit smoking. You will be randomly assigned to one of the apps and complete short surveys to see which works better.
Seattle, WashingtonAges 18 years+ - NCT06142058Recruiting
Targeted therapy for advanced lung cancer
This trial studies how well targeted therapy works for advanced non-small cell lung cancer (NSCLC) that has spread. You may qualify if you have a specific gene change and are starting your first targeted treatment.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06422273Enrolling by invitationPhase 3
TXA vs Saline to Prevent Bleeding After Lung Transplant Biopsy
This trial tests whether a medication called tranexamic acid (TXA) can help prevent bleeding after a lung transplant biopsy. It compares TXA to a saltwater solution (saline) to see if it reduces the need for procedures to stop bleeding.
Grand Rapids, MichiganAges 18 years+ - NCT06897774Recruiting
Testing nerve tap to protect breathing muscle on ventilator
This study tests whether a gentle electrical tap on a nerve near your collarbone (the phrenic nerve) can keep your diaphragm—the main muscle you use to breathe—from getting weak while you're on a ventilator. The goal is to prevent muscle loss and help you breathe better later.
Istanbul, BakirkoyAges 18–80 - NCT04905056RecruitingPhase 2
Ablation treatment for lung ground-glass nodules that don’t go away
This Phase 2 trial studies whether a procedure called “ablation” is safe and effective for certain lung cancers that appear as ground-glass spots on CT scans and do not improve after 3 months. It may help people who cannot fully have surgery for their condition.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06401239Recruiting
Study on recovery from severe breathing problems
This study looks at how recovery goes for people who had severe breathing problems in the hospital. It involves talking with you and a partner who helps care for you, to learn how to improve support for both of you.
Baltimore, MarylandAges 18 years+ - NCT06436638Recruiting
CPAP mask vs. nasal tube for breathing during molar extraction
This trial compares two ways to help you breathe during deep sedation for a molar extraction: a CPAP mask over your nose or a small tube placed in your nostril. The goal is to see which method keeps your oxygen levels more stable.
KayseriAges 18–60 - NCT06123143Recruiting
Finding the best time to stop CPAP in very small babies
This study looks at when to safely take very small babies (born before 30 weeks) off breathing support called CPAP. It aims to find the ideal time to help their lungs grow stronger.
Escondido, CaliforniaAges Up to 7 months - NCT06856525RecruitingPhase 2/Phase 3
MRI scan to study lung health in e-cigarette users
This study tests a new type of MRI scan to see how e-cigarettes affect your lungs. It's for young adults who vape nicotine regularly. The results may help doctors understand vaping-related lung damage.
Durham, North CarolinaAges 18–35 - NCT05416775RecruitingPhase 1/Phase 2
Test drug SHR-8068 for advanced lung cancer
This trial tests SHR-8068 in people with advanced non-small cell lung cancer (NSCLC). It may help by controlling cancer after standard treatments have not worked, and it’s designed to find the right way to give the drug.
Hefei, AnhuiAges 18–75 - NCT07640581Recruiting
RSV Infection Study in Babies Under 2 Years
This study tracks how respiratory syncytial virus (RSV)—a common respiratory infection in babies—affects children under 24 months in Ho Chi Minh City. Researchers want to understand how often RSV happens, how severe it is, and how it impacts families, so they can better prepare healthcare services.
Ho Chi Minh City, Ho Chi MinhAges birth–2 years - NCT06928922RecruitingEarly Phase 1
Inhaled mRNA vaccine for advanced lung cancer and lung metastases
This trial tests an inhaled dry powder vaccine that uses mRNA to help your immune system target cancer cells in the lungs. It is for people with advanced lung cancer or solid tumors that have spread to the lungs, who have already tried standard treatments.
BeijingAges Up to 99 years - NCT06752044Recruiting
Vaccine, immunotherapy, and radiation for advanced lung cancer
This trial tests a combination of a personalized vaccine (made from your tumor's unique markers), a drug that boosts your immune system (PD-1 inhibitor), and targeted radiation for people with advanced lung cancer that has progressed after initial treatment. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Nanchang, JiangxiAges 18–70 - NCT06425406Recruiting
Preventing low oxygen in children during anesthesia with HFNC
This trial tests whether a special oxygen device (HFNC) can prevent low oxygen levels in children during anesthesia. It is for children aged 2-10 who are generally healthy and having surgery.
Zhengzhou, HenanAges 2–10 - NCT07129265Enrolling by invitation
Understanding vape marketing study for youth
This study looks at how young people understand vape marketing. You might join a working group or a focus group to share your thoughts.
Boston, MassachusettsAges 13 years+ - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT06833827Recruiting
Clot removal vs clot-busting drugs for severe lung clots
This study compares two ways to treat a large blood clot in the lungs that is causing life-threatening symptoms. One method uses a device to remove the clot, the other uses medicine to dissolve it.
Leiden, South HollandAges 18 years+ - NCT06221670RecruitingPhase 2
Toripalimab after surgery for high-risk early lung cancer
This trial tests whether giving a drug called Toripalimab after surgery can help prevent early-stage non-squamous non-small cell lung cancer from coming back. It is for people whose tumors have high-risk features and PD-L1 levels of at least 1%.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06436950Recruiting
Diaphragm pacing for weak breathing muscles from the ventilator
This trial tests whether using an electrical device to stimulate the phrenic nerve (which controls the diaphragm) helps patients whose diaphragm has weakened while on a breathing machine in the ICU. It might help restore strength and make it easier to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06816992RecruitingPhase 1
ORIC-114 with amivantamab for EGFR exon 20 insertion lung cancer
This trial tests an experimental pill (ORIC-114) combined with a targeted injection (amivantamab) for a specific type of non-small cell lung cancer that has an EGFR exon 20 insertion mutation. It aims to see if the combination shrinks tumors or delays growth.
New York, New YorkAges 18 years+ - NCT05999214Recruiting
Imaging scan for lung cancer treatment response
This trial uses a special imaging scan (SPECT/CT) with a radioactive tracer to see how well your NSCLC is responding to your first treatment. It may help doctors decide if the treatment is working.
Xi'an, ShaanxiAges 18–80 - NCT06339268Recruiting
Brain and body training to prevent confusion after lung surgery
This study tests whether special physical and brain exercises before and after lung surgery can help older adults (ages 60+) avoid confusion or memory problems. Participants will use a tablet or phone to follow the program.
BelgradeAges 60 years+ - NCT06393179Recruiting
Breathing pattern study for ICU patients on ventilators
This study looks at a specific breathing pattern in very sick patients on a ventilator. Researchers want to find the best way to treat this pattern, which may help you breathe better and recover faster.
Nanjing, JiangsuAges 18 years+ - NCT07089199RecruitingPhase 2
Drug combo before surgery for stage III lung cancer
This trial tests a combination of three drugs (tislelizumab, anlotinib, and nab-paclitaxel) given before surgery for stage III lung cancer that can be removed. The goal is to see if this treatment helps shrink the tumor and improves outcomes.
Jinan, ShandongAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.