Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,764 recruiting studies in this area right now.
By phase
- Not applicable6,413
- Phase 2492
- Phase 1247
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder140
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York254
- Texas209
- Maryland175
- Pennsylvania169
- Florida147
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,764 total
- NCT07326709RecruitingPhase 3
Votoplam for Huntington's disease: a Phase 3 study
This study tests an investigational drug called Votoplam for people with Huntington's disease. It aims to see if the drug can slow progression of symptoms like movement and thinking problems.
Birmingham, AlabamaAges 21–70 - NCT07325279RecruitingPhase 1
Nalmefene Implant Safety Study in Healthy Adults
This trial tests a new implant form of the medicine nalmefene to see if it is safe and well-tolerated in healthy adults. It is an early-phase study that helps researchers understand how the body reacts to the implant before testing it in people with opioid use problems.
Morrisville, North CarolinaAges 18 years+ - NCT07331987Recruiting
Probiotics for mild to moderate anxiety or depression study
This trial tests if probiotics can help reduce symptoms of mild to moderate anxiety or depression. It is for people aged 18–60 who are not currently taking most anxiety or depression medications and who have not used them in the last 2 weeks (except for escitalopram).
Guangzhou, GuangdongAges 18–60 - NCT07326423Enrolling by invitation
Imagery therapy app for autism language skills
This trial tests a computer program that uses mental imagery exercises to help young children with autism improve their language and learning skills. It is designed for children ages 2 to 5.
Foz do Iguaçu, ParanáAges 2–5 - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06865066Recruiting
Online therapy for anxiety during perimenopause
This study tests if an online therapy program (based on cognitive behavioural therapy) can help reduce anxiety in women going through perimenopause. The therapy is done over the internet, so you can participate from home.
Kingston, OntarioAges 40–60 - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT07329283Recruiting
Nighttime nutrition and sleep health study
This study looks at how eating at night affects your sleep and body clock. You will spend two nights in a sleep lab to test the effects of a small meal before bed.
Salt Lake City, UtahAges 18–35 - NCT07332143RecruitingPhase 2
Psilocybin-assisted therapy for PTSD in military members
This study tests whether a drug called psilocybin (the active ingredient in 'magic mushrooms') combined with therapy can help treat PTSD in military personnel and veterans. You'll receive the drug during a supervised session, along with talk therapy, to see if it reduces PTSD symptoms.
Atlanta, GeorgiaAges 18 years+ - NCT07325448Recruiting
Mindfulness study for psychological well-being
This trial tests an 8-week mindfulness program to improve psychological well-being. It requires attending classes in person and undergoing MRI scans in Boston.
Boston, MassachusettsAges 18–50 - NCT07325370Recruiting
Brain training with feedback for anxiety in pregnancy loss
This trial tests if a non-invasive brain training method (neurofeedback) can help women with recurrent pregnancy loss who also have anxiety. It aims to improve heart rate regulation and reduce anxiety using a closed-loop system that gives you real-time feedback.
Shenyang, LiaoningAges 18–45 - NCT07330648RecruitingPhase 2
Crisugabalin for generalized anxiety disorder
This study tests a new investigational drug called crisugabalin for people with generalized anxiety disorder (GAD) who have not found enough relief from at least two other anxiety medications. The trial aims to see if crisugabalin can safely reduce anxiety symptoms.
Hefei, AnhuiAges 18 years+ - NCT07332624Enrolling by invitation
Therapy via text for mild memory problems and mood changes
This study tests if acceptance and commitment therapy (ACT) delivered through instant messaging can help older adults with mild memory issues manage emotional or behavioral symptoms like anxiety, depression, or agitation.
Hong KongAges 50 years+ - NCT07328386Recruiting
Neck surgery for brain lymphatic disorder
This trial tests a neck surgery (lymphaticovenous and lymph node-to-vein anastomosis) to see if it improves symptoms in people with Alzheimer's disease linked to a brain lymphatic circulation disorder. It focuses on those with moderate-stage Alzheimer's and confirmed amyloid buildup.
SeoulAges 19–100 - NCT07330349Recruiting
Trauma and substance use in penetrating abdominal injury
This study looks at alcohol, drug use, and painkiller use in people with a penetrating abdominal injury (like a stab or gunshot wound to the belly). It aims to understand how these substances affect patient outcomes.
Cali, Valle del Cauca DepartmentAges 15 years+ - NCT07325006Recruiting
How Doctors' Behavior Affects Cancer Distress
This study looks at how doctors' behavior affects the distress cancer patients feel. It's for patients who are getting or recently finished radiation at Mayo Clinic in Rochester.
Rochester, MinnesotaAges 18 years+ - NCT07325929Recruiting
Online radical acceptance for social anxiety
This study tests if an online program that teaches radical acceptance skills can help people with social anxiety. You will learn to accept anxious feelings instead of fighting them, which may reduce your social fears.
HaifaAges 18–45 - NCT07333586Recruiting
Insomnia treatment for better insulin sensitivity
This study tests whether treating insomnia can improve how your body uses insulin (a hormone that controls blood sugar). It may help people with excess weight and poor sleep who are at risk for diabetes.
Columbia, MissouriAges 18–50 - NCT07325851Recruiting
Ozone therapy for chronic pain when other options fail
This study is testing ozone therapy as a palliative treatment for people with chronic pain who haven't found relief from other options. It aims to see if adding ozone can improve pain and quality of life.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07333027Recruiting
Loneliness in depression treatment study
This study looks at how loneliness affects people hospitalized for depression. It may help researchers understand how to better support recovery.
Erlangen, BavariaAges 18 years+ - NCT07325474Recruiting
Safety planning for teens after a mental health emergency
This study tests a safety planning program for teens who recently visited an emergency room for suicidal thoughts, self-harm, or a mental health crisis. The program helps teens and their families create a plan to stay safe and get support.
Claremont, New HampshireAges 12 years+ - NCT07333365Recruiting
Mindfulness for young adults
This study tests if an app that uses interactive audio and a ChatGPT-powered mindfulness coach can help improve your overall well-being. It's designed for people aged 18 to 30.
SingaporeAges 18–30 - NCT07332260RecruitingPhase 1
Fecal transplant for Alzheimer's disease
This study tests whether a fecal transplant (transferring healthy bacteria from a donor's stool into your colon) can improve memory and thinking in people with mild to moderate Alzheimer's. You would receive the transplant via colonoscopy and have follow-up brain scans.
Tromsø, TromsAges 18 years+ - NCT07328373Recruiting
Depression Relapse Predictors Study
This trial looks at brain and genetic markers to understand why depression returns. It is for people with major depression who are not currently taking medication.
IstanbulAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,764 recruiting psychiatry studies from the U.S. registry right now, out of 12,350 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.