Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06825403Recruiting
Olfactory training for mild cognitive impairment
This trial tests whether daily scent training can help improve memory and thinking in people with mild cognitive impairment (MCI), a condition that is more than normal aging but not dementia. You would smell different odors at home and track your progress.
New York, New YorkAges 55–89 - NCT06821295RecruitingPhase 2/Phase 3
Smartphone app to help reduce drinking at shelters
This trial tests a smartphone app that gives you personal tips to help you drink less alcohol, especially if you are staying at or getting services from a shelter. The app sends you messages at the right times to help you cut back on drinking.
Oklahoma City, OklahomaAges 18 years+ - NCT06817837Enrolling by invitation
Can hypnosis help adults with brain injury?
This study tests if hypnosis can help adults with stroke or traumatic brain injury who have symptoms like anxiety, trouble sleeping, pain, or behavior issues. Researchers want to see if it's a feasible and useful addition to usual care.
Tinlot, LiègeAges 18 years+ - NCT06817876Recruiting
Care Buddy: Helping dementia caregivers find support
This study tests a new app called Care Buddy that connects family caregivers of people with dementia to community resources. You'll use the app and share your feedback, which could help make caregiving easier.
Singapore, SingaporeAges 21–80 - NCT06823453Recruiting
Training friends and family to support people who use opioids
This study trains friends and family members of people who use opioids, so they can provide better support and reduce stigma. It also includes people who use opioids to see if this training improves their relationship and well-being.
Chicago, IllinoisAges 18 years+ - NCT06817395Recruiting
Thinking and memory in chronic ITP
This study looks at whether chronic or persistent immune thrombocytopenia (ITP) affects thinking and memory. If you have had low platelet counts for 3 months or more and have been treated for ITP, you may help researchers understand how the condition can impact the brain.
Boston, MassachusettsAges 18 years+ - NCT06824415Recruiting
Sleep TMS for depression
This trial tests whether a type of brain stimulation called TMS (transcranial magnetic stimulation), given during sleep, can improve depression. It's for adults who have not gotten enough relief from antidepressant medication.
Stanford, CaliforniaAges 18–65 - NCT05244564Recruiting
PTSD app treatment comparison: monitor vs AR 3MDR
This trial tests whether two different ways of delivering an “AR 3MDR” PTSD therapy work better than a standard computer monitor approach. You may be eligible if you have PTSD and can do the required walking session on a treadmill safely.
Bethesda, MarylandAges 18 years+ - NCT05708001Recruiting
Testing brain stimulation to improve memory in mild impairment
This study tests whether a noninvasive brain stimulation method (tACS) can improve memory in people with mild cognitive impairment (MCI). A caregiver also helps with the stimulation during the study, and success is measured through study visits and memory-related evaluations.
GenevaAges 55–85 - NCT06457841Recruiting
Stress and Resilience in Afro-Descent Adults
This study looks at how stress and resilience affect people who use alcohol or cannabis to cope. It's for adults of Afro-descent who have used alcohol or cannabis at least a few times recently and are not in treatment for substance use.
Dallas, TexasAges 18–30 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT06002763Recruiting
Patient-reported health survey for new mothers
This trial tests whether a simple questionnaire (PROMIS-29) can help measure physical and mental health in women who have recently given birth. It aims to improve follow-up care for all mothers, including those with healthy babies admitted to the NICU.
Toronto, OntarioAges 18–55 - NCT05802446Recruiting
Neurofeedback program for bipolar depression symptoms
This study tests whether “neurofeedback” can reduce leftover (residual) depressive symptoms in people with bipolar I or II. It may help calm mood by training brain activity, alongside stable medication.
Créteil, val-de-marneAges 18–65 - NCT06559826RecruitingPhase 2
Ketamine therapy with or without talk for depression
This study compares ketamine alone to ketamine combined with psychotherapy for treating depression. It may help if you have moderate to severe depression and want to see if adding talk therapy improves results.
New York, New YorkAges 18–90 - NCT06092125Recruiting
Brain disease imaging study with PET/MR scans
This trial uses advanced PET and MR scans to better understand and diagnose brain diseases like Alzheimer's, Parkinson's, epilepsy, and brain tumors. It may help identify new ways to track these conditions.
Beijing, Beijing MunicipalityAges 18–60 - NCT03638583Recruiting
Online testing study to prevent or spot Alzheimer’s early
This study invites people age 50+ who do not have dementia to do ongoing thinking tests online. If an online risk screen suggests you may be at higher risk, you may be referred for in-person body tests (biomarker assessment).
San Diego, CaliforniaAges 50–85 - NCT05946083RecruitingPhase 2
Study links binge drinking, gut bacteria, and brain function
This Phase 2 study looks at how binge drinking may change gut bacteria and how your brain works. You may qualify if you’re a Portuguese-speaking student and your drinking pattern and health history match the study rules.
Braga, Gualtar, BragaAges 18–23 - NCT06194344Recruiting
Personalized imagery for sleep and psychosis in inpatients
This study tests whether personalized guided imagery (a relaxation technique) can help improve sleep, reduce psychosis symptoms, and lower suicidal thoughts in people with schizophrenia or mood disorders with psychotic features who are currently in the hospital.
Houston, TexasAges 18 years+ - NCT06807892Recruiting
Comparing exercise games for thinking and movement in Huntington's disease
This study tests two different types of video game-based exercises to see which one better helps thinking skills, movement, and mood in people with Huntington's disease. You would play these games as part of your care, and the results may guide future therapy choices.
AngersAges 18 years+ - NCT06803823RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's
This study tests an experimental drug, ONO-2020, to see if it can help reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, pacing, or verbal outbursts, and this trial aims to find a new treatment option.
AichiAges 55–90 - NCT06810960Recruiting
Leqembi use in South Korean Alzheimer's patients
This study follows people with Alzheimer's who are already taking Leqembi (lecanemab) after being in the JOY-ALZ study. It collects medical information to check how the treatment works in real-world use.
Nutley, New JerseyAges 19 years+ - NCT06808984RecruitingPhase 2
Testing a new drug for agitation in Alzheimer's disease
This trial tests an investigational drug called BMS-986368 to see if it can safely reduce agitation in people with Alzheimer's disease. You may be able to join if you have Alzheimer's with confirmed biomarkers and experience agitation that has been going on for at least 4 weeks.
Homewood, AlabamaAges 55–90 - NCT06809179RecruitingPhase 2
Nasal spray for social anxiety
This study tests if a new nasal spray called fasedienol helps quickly reduce anxiety in adults with social anxiety disorder. The spray is used as needed in a repeat-dose design, meaning you might use it more than once.
Sherman Oaks, CaliforniaAges 18–65 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.