Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06673966Recruiting
Schizophrenia brain and immune health study
This study looks at how immune system health relates to brain changes in people with schizophrenia. It uses brain imaging and electrical activity tests to understand these connections.
Changsha, HunanAges Any age - NCT06678100Recruiting
Swallowing study for adults with Alzheimer's
This study looks at swallowing problems in people with Alzheimer's disease compared to healthy older adults. If you have Alzheimer's, you'll have a swallowing test and your caregiver will answer questions about your daily life.
Nashville, TennesseeAges 60 years+ - NCT06678880Recruiting
Sleep and light for mood during menopause
This study tests a program that combines better sleep habits with timed bright light exposure to help improve mood in women going through menopause. It may help reduce the sad or hopeless feelings that often come with this transition.
San Diego, CaliforniaAges 45–75 - NCT06677268Recruiting
Sleep and breathing rehab study for COPD patients
This study tests whether a respiratory rehabilitation program improves sleep quality in people with COPD. It may help you breathe better and sleep more restfully.
AmiensAges 50 years+ - NCT06678789Recruiting
Testing low vs high nicotine pouches for smokers
This study compares how low and high nicotine pouches affect adult smokers who want to try a tobacco-free option. You'll attend two visits in Charleston to check health markers.
Charleston, South CarolinaAges 21 years+ - NCT02097706RecruitingPhase 2
Drug study for borderline personality disorder
This Phase 2 study tests a new medicine for people with borderline personality disorder (BPD) to see if it can improve symptoms. You may qualify if you have a confirmed BPD diagnosis and meet safety and medication rules.
Melbourne, VictoriaAges 18–65 - NCT03909477Recruiting
Study of MRI brain scans in cannabis smokers over time
This study follows people who currently or used to smoke cannabis to see how cannabis use may change certain MRI scan signals in the brain over time. You may help researchers understand the effects of cannabis smoking and how brain imaging changes can be measured safely.
London, OntarioAges 18–85 - NCT06436209Recruiting
Brain study on thinking and attention
This study uses brain scans to see how the front part of the brain controls attention and thinking. If you are right-handed and healthy, you may help researchers learn more about how the brain works.
Providence, Rhode IslandAges 18–35 - NCT06559267Recruiting
Training for school staff to support kids at recess
This trial tests a training program for school staff (like paraeducators and teachers) to help them support autistic children and those with other neurodevelopmental disorders during recess. The goal is to make recess more engaging and positive for elementary-aged students.
Los Angeles, CaliforniaAges 5 years+ - NCT06660901Recruiting
Study on cannabis use and vomiting in emergency rooms
This study looks at patients who come to the ER with belly pain or vomiting and uses cannabis, to better understand a condition called cannabinoid hyperemesis syndrome (severe nausea and vomiting caused by long-term cannabis use). If you're eligible, you'll answer a few questions to help doctors learn more.
AngersAges 18–65 - NCT06657768RecruitingPhase 1
Study of LY4006895 for healthy people and those with early Alzheimer's
This trial tests a new medicine called LY4006895 in two groups: healthy volunteers and people with early symptomatic Alzheimer's disease. It aims to see how the drug works in the body and if it might help memory and thinking.
Los Alamitos, CaliforniaAges 45–85 - NCT05840198Recruiting
Dog-assisted therapy for youth in residential care
This study tests whether a structured therapy program with a canine (dog) can improve outcomes for youth receiving residential inpatient services. If you qualify, you would be asked to complete baseline tasks and, if assigned, attend at least one of the dog-therapy sessions over about 6 weeks.
Chicago, IllinoisAges 8–18 - NCT06660212Recruiting
Pelvic health rehab study for women with pain
This study tests whether biomodulation therapy combined with pelvic floor rehabilitation can help women with certain types of pelvic pain. It is for premenopausal women who were born female and are experiencing provoked vestibulodynia (pain at the vaginal opening) with or without vaginismus (tightness).
Ottawa, OntarioAges 18 years+ - NCT06660225Recruiting
Deep brain stimulation for severe OCD
This trial tests if deep brain stimulation (a surgical treatment that uses electrical pulses to adjust brain activity) can help people with severe obsessive-compulsive disorder (OCD) that has not improved with other treatments. It is for adults aged 22 to 75 who have had OCD symptoms for over 5 years.
Dallas, TexasAges 22–75 - NCT06668571RecruitingPhase 2
Ketamine for treatment-resistant depression
This study tests if intravenous ketamine can help people with treatment-resistant depression who haven't found relief from at least two other treatments. If you qualify, you'll receive ketamine infusions to see if it improves your mood.
Rochester, MinnesotaAges 18–65 - NCT06660381RecruitingPhase 1
Psilocybin therapy for cannabis use disorder
This study tests if psilocybin (a substance that can change how you think and feel) can help people reduce or stop using cannabis. You will receive support and be monitored closely throughout the trial.
Baltimore, MarylandAges 18 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06660888Enrolling by invitation
Study of fatigue, depression, and anxiety in people with low thyroid
This study looks at how common fatigue, depression, and anxiety are in people with hypothyroidism (underactive thyroid). It aims to understand if these symptoms are linked to thyroid hormone levels.
Asyut, AssuitAges 18–60 - NCT06666777Recruiting
Speech therapy and parenting for early communication skills
This study tests a program that combines speech therapy with parenting support to help young children with developmental delays improve their communication and social skills. It is designed for children aged 6 months to 5 years who have developmental challenges, and their parents.
Como, ComoAges 6 months–4.9 years - NCT06665074RecruitingPhase 2
Inflammation and aggression study
This trial tests how inflammation affects aggression by giving a small amount of a substance that briefly triggers your immune system. You may qualify if you have a diagnosis of Intermittent Explosive Disorder (IED), or if you are a healthy control without current anger issues.
Columbus, OhioAges 21–55 - NCT06665984Recruiting
Greater Houston pediatric bipolar registry study
This study is creating a registry to learn more about bipolar disorder in children and teens. It includes youth who have bipolar disorder and those who have a parent with bipolar disorder, as well as healthy youth for comparison.
Houston, TexasAges 6–17 - NCT06661460Recruiting
Online therapy for youths with anxiety disorders
This study tests an online cognitive behavioral therapy program for children and teens (8 to 17 years old) who have specific anxiety disorders. It aims to help reduce anxiety symptoms by providing therapy through a smartphone, tablet, or computer, with support from a caregiver.
Kalmar, Region Kalmar LänAges 8–17 - NCT06661031Enrolling by invitation
Cannabis use help for young adults via phone app
This study tests a new program that combines telehealth coaching and a smartphone app to help young adults who use cannabis a lot to cut back or quit. If you are a patient at certain Boston clinics and use cannabis on most days, this study might be a good fit for you.
Boston, MassachusettsAges 18–26 - NCT06662409Recruiting
Reflexology support for grieving cancer caregivers
This study offers support to people who are caring for a loved one with cancer and have experienced the loss of that person. You will learn and perform reflexology (a type of foot/hand massage) as a way to help yourself and others cope with grief.
East Lansing, MichiganAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.