Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06661564Recruiting
Testing tears for Alzheimer's disease diagnosis
This study looks at whether tears can help detect Alzheimer's disease. You will have your tears collected and tested for possible biomarkers.
Tours, FranceAges 18 years+ - NCT06664333Recruiting
Siblings' experiences when a brother or sister is in the ICU
This study explores what it's like for children and teenagers when their brother or sister is in the pediatric intensive care unit (PICU). By talking with siblings, researchers hope to better understand their feelings and needs.
ParisAges 9–18 - NCT06669182Recruiting
Cerebellar TMS for Alzheimer's Disease
This trial uses a non-invasive brain stimulation technique (TMS) to target the cerebellum in people with Alzheimer's disease. It aims to see if this treatment can improve symptoms and cognitive function.
Xi'an, ShaanxiAges 50–85 - NCT06665854Enrolling by invitation
Rhythm therapy for first-time mothers
This study tests whether rhythm therapy (like gentle music or movement) during pregnancy helps strengthen the bond between you and your baby, supports your baby's learning, and reduces stress. It is for first-time mothers who are between 20 and 27 weeks pregnant.
Sakarya, SerdivanAges 18 years+ - NCT06661031Enrolling by invitation
Cannabis use help for young adults via phone app
This study tests a new program that combines telehealth coaching and a smartphone app to help young adults who use cannabis a lot to cut back or quit. If you are a patient at certain Boston clinics and use cannabis on most days, this study might be a good fit for you.
Boston, MassachusettsAges 18–26 - NCT06668571RecruitingPhase 2
Ketamine for treatment-resistant depression
This study tests if intravenous ketamine can help people with treatment-resistant depression who haven't found relief from at least two other treatments. If you qualify, you'll receive ketamine infusions to see if it improves your mood.
Rochester, MinnesotaAges 18–65 - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06660888Enrolling by invitation
Study of fatigue, depression, and anxiety in people with low thyroid
This study looks at how common fatigue, depression, and anxiety are in people with hypothyroidism (underactive thyroid). It aims to understand if these symptoms are linked to thyroid hormone levels.
Asyut, AssuitAges 18–60 - NCT06660212Recruiting
Pelvic health rehab study for women with pain
This study tests whether biomodulation therapy combined with pelvic floor rehabilitation can help women with certain types of pelvic pain. It is for premenopausal women who were born female and are experiencing provoked vestibulodynia (pain at the vaginal opening) with or without vaginismus (tightness).
Ottawa, OntarioAges 18 years+ - NCT05731414Recruiting
Testing behavior programs to improve outcomes in schizophrenia
This study looks at how a behavioral program (including remediation and behavior-based techniques) may improve outcomes for adults with schizophrenia-spectrum conditions. You may be eligible if you meet basic age/language needs and haven’t done certain therapies recently.
Scarborough Village, OntarioAges 18–65 - NCT04532424Recruiting
Brain stimulation for repetitive behaviors in autism
This trial tests whether transcranial magnetic stimulation (a non-surgical treatment using magnets on the scalp) can reduce restricted and repetitive behaviors seen in autism. It’s designed for people with autism who have high levels of certain repetitive behaviors, like insistence on sameness or unusual interests.
Stanford, CaliforniaAges 12–45 - NCT06390462Recruiting
Counseling for teens in school-based primary care
This study tests a brief counseling approach called Interpersonal Counseling for Adolescents (IPC-A) in school settings. It aims to help teens with emotional or social challenges before they become more serious, and it's designed for those who aren't already in mental health treatment.
HämeenlinnaAges 13–16 - NCT06656416RecruitingPhase 2
Study of ALTO-100 for bipolar depression
This study tests an investigational drug called ALTO-100 for people with bipolar disorder who are currently experiencing depression. It aims to see if ALTO-100 can help improve depressive symptoms when added to your current mood stabilizer or antipsychotic medication.
Birmingham, AlabamaAges 18–70 - NCT06655883RecruitingPhase 3
Testing suvorexant for insomnia in people with opioid use disorder
This study tests whether the sleep medication suvorexant (Belsomra) can help people with opioid use disorder who also have trouble sleeping. If you are stable on medication for opioid use disorder and have not used opioids in the last month, this trial may be an option for you.
Garden Grove, CaliforniaAges 18–70 - NCT06651567RecruitingPhase 2
Study of a new drug for agitation in Alzheimer's disease
This study tests an experimental medication, ITI-1284, to see if it can safely reduce agitation in people with Alzheimer's disease. Agitation can include restlessness, aggression, or irritability, and this drug aims to help manage those symptoms.
Anaheim, CaliforniaAges 55 years+ - NCT06650267RecruitingPhase 2
Substance use and family violence treatment for fathers
This study tests a treatment program for fathers who have both a substance use disorder and a history of family violence within the last 18 months. The goal is to see if the program helps reduce substance misuse and improve family relationships.
New Haven, ConnecticutAges 18 years+ - NCT06650527Recruiting
Empathy training for dementia caregivers
This study tests a cognitive empathy training program for people caring for a family member with dementia. The training is designed to help caregivers better understand their loved one's perspective and reduce stress. You may benefit if you live with the person you care for and feel burdened by your caregiving role.
Atlanta, GeorgiaAges 50 years+ - NCT06651684Recruiting
Quit smoking help for parents with social needs
This trial tests if health navigators can help parents who smoke and have unmet social needs to quit smoking. If you smoke and face challenges like trouble paying bills or finding childcare, this program may support you.
Montreal, QuebecAges 18 years+ - NCT06651333Recruiting
Brain scans during opioid addiction treatment
This study uses brain scans to understand how methadone or buprenorphine treatment affects the brain, with the goal of helping people stay in treatment and avoid relapse. You would need to be recently started on one of these medications and be able to undergo MRI scans.
Hartford, ConnecticutAges 18–50 - NCT06649084Enrolling by invitation
Language treatment study for primary progressive aphasia
This study tests a multi-component language treatment for people with primary progressive aphasia (a type of dementia that first affects language). It aims to help improve communication skills with support from a study partner.
Austin, TexasAges Any age - NCT06651086Recruiting
Executive functioning help for children in therapy
This study tests a new way to help children with executive functioning challenges (like planning and staying organized) in therapy. It's for kids ages 6-12, with or without autism, who are getting therapy at publicly funded clinics.
San Diego, CaliforniaAges 6–99 - NCT06649916Recruiting
Learning words from parent speech in autistic children
This study looks at how autistic and non-autistic toddlers learn new words when parents talk to them in a special, engaging way. It may help understand how to support language development.
Richardson, TexasAges 1.5 years–4.9 years - NCT06651801Recruiting
Virtual group visits for anxiety or depression
This study tests whether regular online group sessions with a doctor can help adults with anxiety or depression. You would join a small video call group every other week for 6 months.
Winnipeg, ManitobaAges 18 years+ - NCT06656533Recruiting
Timing of brain stimulation to improve insomnia treatment
This study tests whether giving a specific type of brain stimulation (rTMS) at the right time can help make insomnia treatment work better. It may be an option for people ages 25 to 45 who have trouble sleeping and live near Stanford University.
Palo Alto, CaliforniaAges 25–45
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.