Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06426303RecruitingPhase 4
Alcohol Use Disorder Treatment in Veterans: Brain and Inflammation
This study is for veterans with alcohol use disorder who have been sober for 5 days to 3 weeks. It looks at how trauma, inflammation, and brain function relate to alcohol problems and how well treatment works. You will be in a group that gets medication or a placebo.
Portland, OregonAges 18–60 - NCT06430333RecruitingPhase 2
Sleep therapy to prevent depression in pregnancy
This study tests whether a sleep-focused therapy can help prevent depression in pregnant people who have insomnia. If you are 14–31 weeks pregnant and have trouble sleeping, this trial offers a program to improve your sleep and lower your risk of depression.
Novi, MichiganAges 18 years+ - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT06429956Recruiting
Combined online therapy for anxiety and depression
This trial tests a new type of therapy that combines different treatment methods for anxiety and depression. It is completely online, so you can join from home, and it aims to help you feel better by tailoring the therapy to your needs.
AarhusAges 18 years+ - NCT06426602Enrolling by invitation
Brain communication trial for disorders of consciousness
This trial tests a new way to help people with disorders of consciousness (like locked-in syndrome) communicate using their brain activity. The goal is to see if a special system can unlock better communication for those who have limited ability to speak or move.
Pittsburgh, PennsylvaniaAges 16–65 - NCT06439992Recruiting
New PET scan tracer to detect Alzheimer's in the brain
This study tests a new PET imaging tracer called Fluselenamyl to see how well it shows amyloid plaques (a protein linked to Alzheimer's) in the brain. It may help improve early diagnosis for people with Alzheimer's or support research in healthy volunteers.
St Louis, MissouriAges 18 years+ - NCT06431659Enrolling by invitation
Palliative care guide study at nursing homes
This study tests a guide to improve palliative care for nursing home residents. It focuses on making sure their wishes are respected and they receive appropriate support.
Stockholm, Region StockholmAges 65–130 - NCT06426953Recruiting
Proteins in blood to predict confusion after surgery in older diabetics
This study looks at proteins in your blood (TGF-β and INS-PI3K-AKT) to see if they can predict confusion after surgery (postoperative delirium) in older adults with diabetes. It may help doctors identify who is at higher risk.
Duyun, GuizhouAges 65 years+ - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06420557Recruiting
Reducing fear of animals with brain feedback
This study uses brain scans to help people with animal phobias reduce their fear without consciously trying. It tests a new method that may make fear responses weaker over time.
Los Angeles, CaliforniaAges 18–65 - NCT06425237Recruiting
Aromatherapy and music for stress during brain scan
This study tests if calming scents (aromatherapy) and relaxing music can help reduce stress during a brain artery scan (cerebral arteriography). If you are scheduled for this scan, the study may offer a way to feel more at ease during the procedure.
RouenAges 18 years+ - NCT06431087Recruiting
mindfulness for stress reduction in a hospital community
This study tests a mindfulness program called 'Healthy Under Stress' to see if it helps reduce stress. It is open to employees, patients, and family members at the Robert-Bosch-Krankenhaus and Bosch Health Campus.
Stuttgart, Baden WürtenbergAges 18 years+ - NCT06437132Enrolling by invitation
Digital Thanotyping for End-of-Life Care in Dementia
This study tests a digital system (called 'thanotyping') to better understand the last stages of life in people with dementia who live in nursing homes. The goal is to improve care and support for both patients and families during this time.
Bergen, VestlandAges 65 years+ - NCT06432465Recruiting
Brain stimulation to help prevent opioid relapse
This study uses a type of brain stimulation called tDCS (transcranial direct current stimulation) to see if it can help people who have recently started medication for opioid dependence (buprenorphine or methadone) stay on track and avoid relapse. The treatment is non-invasive and involves a mild electrical current applied to the scalp.
Providence, Rhode IslandAges 21–60 - NCT06425211Recruiting
Pelvic Floor Therapy for ED & Premature Ejaculation
This trial tests if pelvic floor therapy (exercises) can help men with erectile dysfunction or premature ejaculation. It may be a drug-free option to improve your sexual health.
Bogotá, CundinamarcaAges 18–100 - NCT06153316Recruiting
How school shootings affect students and staff
This study looks at how experiencing a school shooting impacts students, teachers, and principals. It compares schools that had a shooting to those that did not, to understand the effects on wellbeing.
New York, New YorkAges 11–65 - NCT06411158Recruiting
Pelvic floor training for urine leakage after first baby
This study tests whether a pelvic floor training program delivered through a smartphone app can help first-time moms who leak urine after childbirth. The program is designed for women who had a vaginal delivery with certain risk factors for ongoing pelvic floor issues.
San Diego, CaliforniaAges 18 years+ - NCT06404684Recruiting
Psychological treatment for paraphilic disorders
This trial is testing a psychological treatment (cognitive behavioral therapy, or CBT) for people with paraphilic disorders – conditions where someone has intense sexual urges or behaviors that are unusual or cause distress. The goal is to see if this therapy can help reduce risky behaviors and improve well-being.
Stockholm, Stockholm CountyAges 18 years+ - NCT06413433RecruitingPhase 3
Solriamfetol for binge eating disorder
This study tests whether a drug called solriamfetol can help reduce binge eating episodes. It works on brain chemicals involved in mood and appetite control.
Encino, CaliforniaAges 18–55 - NCT06413420Recruiting
Pregnancy registry for narcolepsy or sleep apnea treatments
This study tracks the health of pregnant women who have narcolepsy or sleep apnea, or who have taken certain wake-promoting medications during pregnancy. It helps researchers learn more about the safety of these treatments for mothers and babies.
Morrisville, North CarolinaAges Any age - NCT06419959Recruiting
NightWare app for veterans with PTSD and sleep problems
This study tests a smartwatch app called NightWare that may reduce nightmares and improve sleep in veterans with PTSD. It could also help heart health by improving sleep quality.
Aurora, ColoradoAges 22–88 - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06418178RecruitingPhase 2
Optimizing MDMA therapy dose for PTSD in veterans
This trial tests different doses of MDMA (a drug sometimes called 'ecstasy') combined with therapy to see which dose works best for treating PTSD in veterans. The goal is to find a safer, more effective dose to help reduce PTSD symptoms.
The Bronx, New YorkAges 18 years+ - NCT06399653Recruiting
Nerve stimulation for alcohol use disorder in veterans
This study tests a non-invasive device that gently stimulates a nerve in your neck (the vagus nerve) to see if it can help reduce alcohol cravings and improve daily functioning. It is designed for veterans who struggle with heavy drinking and want to explore a new treatment option.
San Diego, CaliforniaAges 21–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
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- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.