Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05389787Recruiting
Brain stimulation to improve thinking in schizophrenia
This pilot study tests whether stimulating the cerebellum (a part of the brain) using TMS can improve brain function and thinking in people with schizophrenia. If you qualify, you may receive TMS and undergo brain/cognitive assessments to see whether it helps.
New York, New YorkAges 18–60 - NCT05587127Recruiting
CBT therapy for eating anxiety in functional stomach pain
This trial tests an “exposure-based” type of cognitive behavioral therapy (CBT) to help people with functional dyspepsia (stomach discomfort after eating) who avoid or restrict food. The goal is to reduce food fear and improve eating and weight, after other medical causes have been ruled out.
Boston, MassachusettsAges 18 years+ - NCT06268080Recruiting
Sedation depth and mental recovery after surgery for older adults
This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
Grafton, AucklandAges 55 years+ - NCT06215235Recruiting
Bright light therapy for depression in intellectual disability
This trial studies how bright light therapy (using a special lamp) is being used to help people with intellectual disabilities who have depression. It involves staff, family members, and patients to see how the therapy works in real life.
RotterdamAges 18 years+ - NCT06291870Recruiting
Predicting long-term effects after COVID-19
This study looks at what happens to your thinking and daily health after COVID-19, especially if you have sleep apnea. It aims to find out who is more likely to have ongoing problems.
Detroit, MichiganAges 18 years+ - NCT05973851RecruitingPhase 3
Six-week medicine boost for depression after first treatment failure
This study tests a more intensive antidepressant medicine approach for people whose first tried treatment didn’t work well enough. It compares the intensified treatment with usual care, aiming to improve depression symptoms and daily functioning.
InnsbruckAges 18–65 - NCT05958875RecruitingPhase 4
Six-week medicine switch for schizophrenia after first treatment failure
This trial tests whether a more intensive medication approach for schizophrenia (or related conditions) helps people who didn’t improve on their first tried medicine. Participants will usually switch medicines and be compared against “treatment as usual.”
InnsbruckAges 18–70 - NCT06291233Enrolling by invitation
Interview training for autistic adults seeking jobs
This study helps autistic adults who are in job training programs find and keep jobs. You'll learn interview skills and get support to build your career.
Oceanside, CaliforniaAges 16–26 - NCT06290778Enrolling by invitation
Mental health prevention training for fire fighter trainees
This study tests a program where peers teach emotion regulation skills to help prevent mental health issues in new fire fighters. You would be asked to complete surveys and attend training sessions.
Waco, TexasAges 21 years+ - NCT06284382Recruiting
Early trauma and brain smell test study
This study looks at how early childhood trauma affects brain chemistry, specifically a chemical called dopamine, during smelling tasks. You will have brain scans and smell tests to see if your brain reacts differently.
BronAges 18–30 - NCT06278922Recruiting
A therapy toolkit for Deaf people with alcohol and trauma issues
This study tests a therapy toolkit designed for Deaf or hard-of-hearing people who struggle with alcohol use and have experienced trauma. The therapy is provided in ASL via video sessions, and the goal is to see if it helps reduce drinking and PTSD symptoms.
Worcester, MassachusettsAges 18 years+ - NCT06289010Recruiting
Family therapy for childhood depression: brain study
This study tests whether a family-focused therapy can help children ages 7 to 12 with depression. It looks at how the brain changes during treatment using an MRI scan.
Boston, MassachusettsAges 7–12 - NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06276400Recruiting
Brain activity study of emotion and time perception
This study uses brain imaging and mild magnetic stimulation to understand how the brain processes emotions and estimates time. It may help if you are a right-handed English speaker between 18 and 45 with normal vision.
Santa Barbara, CaliforniaAges 18–45 - NCT06293040RecruitingPhase 1
Cannabis and Alcohol Impairment Study
This study tests how vaporized cannabis and alcohol together affect your ability to drive or perform tasks. It is for healthy adults who have used both substances before.
Baltimore, MarylandAges 21 years+ - NCT06284655Recruiting
A short education program for adults with ADHD
This trial tests whether a brief educational program helps adults with ADHD better understand their condition and manage it. If you have an ADHD diagnosis and speak a Scandinavian language, you may be able to join.
TrondheimAges 18–65 - NCT06285708Recruiting
Making PTSD therapy safer for people with suicidal thoughts
This study tests whether a type of therapy called Prolonged Exposure can be more effective and safe for people who have both PTSD and suicidal thoughts. The goal is to help reduce trauma symptoms while addressing suicide risk.
Columbus, OhioAges 18 years+ - NCT06286202Recruiting
Cognitive skills program for schizophrenia recovery
This trial tests a community-based program called INSPIRE that uses mental exercises and social coaching to help people with schizophrenia or schizoaffective disorder improve their thinking skills and daily functioning. It is conducted in English and requires at least 10 years of English-language education.
SingaporeAges 21–60 - NCT06278779RecruitingPhase 4
Comparing two types of ketamine for stubborn depression
This study compares two forms of ketamine to see which works better for depression that hasn't improved with at least two other antidepressants. If you've tried multiple antidepressants without success, this trial might help find a more effective treatment.
Camperdown, New South WalesAges 18 years+ - NCT06285448Enrolling by invitation
Lecanemab registry and outcome study
This study looks at how well lecanemab (a new Alzheimer's treatment) works in real-world clinics. It also tracks how patients and their care partners do over time. If you are already getting or eligible for lecanemab, you might join with your care partner.
Saint Paul, MinnesotaAges 18 years+ - NCT06279247Recruiting
Body fluid markers in people with narcolepsy
This study looks at the proteins and other chemicals in body fluids (like blood or spinal fluid) of people with narcolepsy. The goal is to find markers that could help doctors better understand and diagnose narcolepsy.
Jinan, ShandongAges 5–100 - NCT06287216Recruiting
A mental health program comparison study
This trial compares a new mental health program to standard care for adults. It studies if the program helps improve well-being.
Ottawa, OntarioAges 18 years+ - NCT06289348Recruiting
How is PKU announced to families after newborn screening?
This study talks to parents or doctors about how they first learned their child had PKU through newborn screening. It aims to improve how these rare metabolic diseases are communicated to families.
ParisAges 18 years+ - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.