Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06291675Recruiting
Hormone therapy's effect on heart and organ fat
This study uses MRI scans to see how gender-affirming hormone therapy affects heart muscle, heart function, and fat in the heart, liver, and pancreas. It may help us understand long-term health effects of hormone therapy.
Vienna, State of ViennaAges 18 years+ - NCT06286774Recruiting
Sleep and alcohol treatment study
This study tests whether improving sleep through cognitive behavioral therapy (CBT-I) can help reduce heavy drinking in people with both alcohol use disorder and insomnia. It might be a good fit if you have trouble sleeping and drink heavily.
Columbia, MissouriAges 18–49 - NCT06290258RecruitingPhase 1/Phase 2
Fecal transplant for autism with stomach issues
This study tests if transplanting healthy bacteria into the gut can help children and young adults with autism who also have stomach problems. It aims to improve both digestive and behavioral symptoms.
Taoyuan CityAges 7–30 - NCT06293040RecruitingPhase 1
Cannabis and Alcohol Impairment Study
This study tests how vaporized cannabis and alcohol together affect your ability to drive or perform tasks. It is for healthy adults who have used both substances before.
Baltimore, MarylandAges 21 years+ - NCT06289569Recruiting
Home therapy for recovery after stroke-related dementia
This trial tests a home-based therapy program for people who have had a stroke that led to vascular dementia. The therapy focuses on improving arm and hand movement, and it is done remotely with a caregiver's help.
Houston, TexasAges 18–110 - NCT06278779RecruitingPhase 4
Comparing two types of ketamine for stubborn depression
This study compares two forms of ketamine to see which works better for depression that hasn't improved with at least two other antidepressants. If you've tried multiple antidepressants without success, this trial might help find a more effective treatment.
Camperdown, New South WalesAges 18 years+ - NCT06285448Enrolling by invitation
Lecanemab registry and outcome study
This study looks at how well lecanemab (a new Alzheimer's treatment) works in real-world clinics. It also tracks how patients and their care partners do over time. If you are already getting or eligible for lecanemab, you might join with your care partner.
Saint Paul, MinnesotaAges 18 years+ - NCT06292078Recruiting
School program to prevent opioid misuse and exclusion
This trial tests a school-wide program called ISLA that aims to reduce opioid misuse and keep students in school. It will involve all staff and 7th graders at participating middle schools in Oregon.
Capitola, CaliforniaAges 8–15 - NCT06277661Recruiting
Mom and Infant Outcomes Study
This study tests a program to support pregnant people who have had high blood pressure, diabetes, or depression/anxiety. It aims to improve outcomes for both mothers and babies.
Columbus, OhioAges Any age - NCT06292741Recruiting
Autonomic system test in people with memory loss
This study tests how the body's automatic functions (like heart rate and blood pressure) change in people with mild memory loss. It may help find early signs of nervous system problems.
Rome, LazioAges 50–85 - NCT06289348Recruiting
How is PKU announced to families after newborn screening?
This study talks to parents or doctors about how they first learned their child had PKU through newborn screening. It aims to improve how these rare metabolic diseases are communicated to families.
ParisAges 18 years+ - NCT06284382Recruiting
Early trauma and brain smell test study
This study looks at how early childhood trauma affects brain chemistry, specifically a chemical called dopamine, during smelling tasks. You will have brain scans and smell tests to see if your brain reacts differently.
BronAges 18–30 - NCT06294106Recruiting
Brain stimulation for PTSD in veterans and first responders
This study tests a new type of brain stimulation (eTMS) to help reduce PTSD symptoms in veterans and first responders. It uses an MRI to guide the treatment, and aims to see if it can improve your quality of life.
Roanoke, VirginiaAges 18–65 - NCT05973786RecruitingPhase 3
Six-week medicine boost for bipolar depression after first treatment fails
This trial tests whether a stronger, more active medication plan for six weeks helps people with bipolar depression who did not improve with their first prescribed treatment. It compares the intensified medication plan to usual care to see which approach works better.
InnsbruckAges 18 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT04389437Recruiting
Eye imaging study for people with memory problems
This study uses detailed eye scans to look for changes that might relate to memory problems. You may be able to join if you are being seen for memory concerns and meet the health and eye-scan requirements.
ParisAges 18 years+ - NCT05895344Recruiting
Compare proton vs modern radiation effects on thinking
This study compares two types of radiation—proton therapy versus modern fractionated radiation—to see how they affect long-term thinking (cognitive function) and daily abilities in people with a specific skull-base tumor. It may help clarify which radiation approach best protects brain and nerve function over time.
CaenAges 18–70 - NCT05665491Recruiting
Study links parent anxiety thinking to child anxiety
This study looks at how a parent’s tendency to interpret situations as more threatening or worrying may affect a child’s anxiety. If you and your child fit the requirements, you may complete questionnaires and phone-based check-ins to help researchers understand what patterns matter.
Belmont, MassachusettsAges 7 years+ - NCT05943652Recruiting
Study of how functional overlay affects movement disorders
This study looks at movement disorders that are functional (not caused by damage to the nervous system) or non-functional, and how a “functional overlay” may change symptoms. It is observational, meaning it does not test a new treatment, but it may help researchers better understand these differences and improve care.
Graz, StyriaAges 18–18 - NCT06269627RecruitingPhase 4
Brain activity study for alcohol use treatment
This trial tests how the medication acamprosate affects brain activity in people with moderate to severe alcohol use disorder. It may help researchers understand how this treatment works.
Bethesda, MarylandAges 21–65 - NCT06252883Recruiting
Video calls to reduce stress for NICU parents
This trial tests whether regular video calls from the NICU bedside help lower stress for parents whose babies stay in the NICU for at least a week. If you're a parent of a newborn in the NICU, this study might offer extra support.
Chicago, IllinoisAges 1 week–2 months - NCT06269952Recruiting
Study on violence among people who inject drugs
This study looks at how common intimate partner violence is among people who inject drugs and what risk factors or experiences are involved. It may help understand the challenges you face and improve support.
StockholmAges 18 years+ - NCT06257095Recruiting
Phone Support Program for Older Adults Leaving APS
This study is testing a phone-based support program for older adults who have been helped by Adult Protective Services and are now moving on. College students in health fields will provide friendly, weekly check-in calls to help with social and emotional needs.
Houston, TexasAges 65 years+ - NCT06269510Recruiting
Study to help alcohol-related liver disease patients drink less
This study is testing new ways to help people with alcohol-related liver disease reduce their drinking. Researchers will check if a program offered through your regular liver clinic can help you drink less and stay healthier.
Detroit, MichiganAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.