Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT07464886RecruitingPhase 3
NAC and mindfulness therapy for depression in youth
This study tests whether a supplement called N-acetylcysteine (NAC) combined with a type of therapy called Mindfulness-Based Cognitive Therapy (MBCT) can help improve depression in teenagers and young adults. It looks at how these treatments affect brain chemicals and may reduce symptoms.
Cincinnati, OhioAges 15–24 - NCT06368726Enrolling by invitationPhase 1
Brain stimulation for kids with autism and genetic changes
This trial tests a gentle brain stimulation treatment called tDCS for children with autism or related conditions who also have certain genetic changes. It may help improve symptoms if your child meets the specific health and birth history requirements.
Albuquerque, New MexicoAges 6–11 - NCT06997549Recruiting
Review of mental health treatment outcomes
This study looks back at information from a large database of people who received mental health treatments. It aims to understand how well treatments worked and what factors influenced outcomes.
Malvern, PennsylvaniaAges 5–100 - NCT07511088Recruiting
Study of a supplement for mild stress in healthy adults
This study tests a dietary supplement for people who experience mild stress or anxiety at least once a week. You will fill out surveys on your phone or computer to see if the supplement helps you feel calmer.
San Francisco, CaliforniaAges 18–60 - NCT07655232Recruiting
Behavioral program for depression in nursing homes
This study tests a behavioral program designed to help skilled nursing facility residents with depression. The program aims to improve mood and quality of life.
Boston, MassachusettsAges 18 years+ - NCT07044752Enrolling by invitation
Anxiety prevention program for Paterson residents
This study tests a program to help prevent anxiety. It is for people who live in Paterson and can read and speak English.
Paterson, New JerseyAges 13–21 - NCT06660199Recruiting
Text Support for Parents of Teens After a Suicidal Crisis
This study tests a text-message program to support parents of teens who come to the ER after suicidal thoughts or attempts. The goal is to see if the program helps parents and teens after they go home.
Ann Arbor, MichiganAges 13 years+ - NCT07653022Enrolling by invitation
Turkish symptom questionnaire for Turkish speakers with language barriers
This study tests a Turkish version of a questionnaire for Turkish-speaking patients who have psychological complaints but face language barriers. It aims to help doctors better understand their symptoms.
Jette, Brussels CapitalAges 18 years+ - NCT06264154Recruiting
Can e-cigarette flavor help you quit smoking?
This study looks at whether the flavor of an e-cigarette can help people who keep smoking switch completely away from regular cigarettes. Participants will use e-cigarettes with different flavors for 6 weeks.
Philadelphia, PennsylvaniaAges 21 years+ - NCT07546604Enrolling by invitation
Game-like app to prevent alcohol and mental health risks in women
This trial tests a smartphone app designed to help women prevent alcohol misuse and mental health problems. You play games in the app to build healthy habits.
Los Angeles, CaliforniaAges 18–69 - NCT05655754RecruitingPhase 4
Tests anesthesia options for ECT in severe depression
This trial compares two anesthesia medicines—esketamine plus propofol versus methohexital—for people receiving ECT (electroconvulsive therapy) for severe depression. The goal is to see which anesthesia approach works better and is safer for patients during ECT.
ViennaAges 18 years+ - NCT07494305RecruitingPhase 2
Testing a new drug for bipolar depression
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
Bentonville, ArkansasAges 18–65 - NCT07506421Recruiting
Hope groups for parenting and mental health
This study tests a program called Hope Groups that helps refugee parents and caregivers with parenting and mental health. You would attend group sessions with other parents to learn and share experiences.
JerashAges 18 years+ - NCT06479499Recruiting
Pilates vs aerobic exercise for breathing and anxiety in COPD
This trial compares Pilates exercises with aerobic exercises to see which is better at reducing shortness of breath, improving daily function, and lowering anxiety in people with moderate COPD.
Lahore, Punjab ProvinceAges 45–65 - NCT07481513Recruiting
Intermittent fasting for perimenopausal women's mental health
This study tests whether intermittent fasting can improve mental health in women going through perimenopause (the years around menopause). If you're a woman aged 45-55 in this stage and not on certain treatments, this trial may help you understand how diet affects your mood.
BeirutAges 45–55 - NCT06474221Recruiting
Testing a therapy to reduce suicide risk in teens
This study tests a therapy called EBPSI for teenagers who have attempted suicide within the past month. The goal is to see if the therapy can help lower the risk of future suicide attempts.
Bengaluru, KarnatakaAges 12–18 - NCT07486804Recruiting
Brain stimulation to help teens who self-injure
This study tests if a gentle, non-invasive brain stimulation technique (like wearing a special cap) can help teenagers who hurt themselves on purpose. It compares two types of stimulation to see which one reduces the urge to self-injure.
Hefei, AnhuiAges 12–22 - NCT07496879Enrolling by invitation
Virtual tour app for first-time mothers
This trial tests whether a QR-code-based virtual tour of the delivery room can help first-time pregnant women feel more prepared and have better childbirth experiences. You would use your smartphone to take a virtual tour before giving birth.
Erzurum, YakutiyeAges 18–45 - NCT07017023RecruitingEarly Phase 1
Blood pressure meds and activity scheduling for low mood
This study tests if taking a blood pressure medication (losartan) combined with a simple scheduling of pleasant activities can help improve low mood. It aims to see if these treatments work better together.
Oxford, OxfordshireAges 18–65 - NCT07040462Recruiting
Parent-child therapy after the 2023 Turkish earthquake
This study tests a therapy for young children (ages 3–6) and their parents who lived through the 2023 Kahramanmaraş earthquake. It aims to help kids heal from trauma by improving the parent-child bond through weekly sessions.
Istanbul, IstanbulAges 3–65 - NCT07494110Recruiting
Aurora: AI storytelling for emotional wellbeing
This study tests a guided, AI-based storytelling tool to help people process their experiences and feel better emotionally. Depending on who you are, the session lasts 1 to 4 hours.
Barcelona, BarcelonaAges 18 years+ - NCT07123194Recruiting
Art program to help teens build healthy digital habits
This study tests whether a nursing program that uses art activities can help 6th graders build healthier digital habits, reduce cyberbullying, and feel more confident in themselves. You would attend group sessions and do creative projects to learn about using technology wisely.
Konya, KaratayAges 11–15 - NCT07528261Recruiting
Support Group for Family Caregivers of Stroke Survivors
This study tests whether a support group using acceptance and commitment therapy (a type of counseling that helps people cope with stress) can reduce caregiver burden and distress. You would meet online with other people caring for stroke survivors.
Alameda, CaliforniaAges 40 years+ - NCT06484088RecruitingEarly Phase 1
Brain scanning study of frustration in healthy adults
This study looks at how the brain handles frustration in healthy adults using a special brain scanner called magnetoencephalography (MEG). It may help researchers understand normal brain responses to frustration.
Bethesda, MarylandAges 18–55
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.