Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT06765057RecruitingPhase 2/Phase 3
Probiotics for Depression and Metabolic Health
This trial tests whether taking a probiotic supplement can improve both depression symptoms and metabolic health (like waist size, blood sugar, and cholesterol) in people with major depression. It may be a good fit if you are already on an antidepressant and have signs of metabolic syndrome.
Riyadh, Riyadh RegionAges 18–65 - NCT06508710RecruitingPhase 3
Ketamine plus venlafaxine for severe depression
This trial tests whether adding ketamine to the antidepressant venlafaxine helps relieve severe depression faster than venlafaxine alone. If you are hospitalized for a serious depression and you meet safety criteria, you may be eligible.
Le Kremlin-Bicêtre, FranceAges 18–65 - NCT06716034Recruiting
Mood and diet pilot trial for teens with depression
This study tests whether a special diet can help improve mood in teens with depression. You and your parent will work together online with the study team.
Toronto, OntarioAges 11–17 - NCT07689526Recruiting
BabaCare: Testing a Care Copilot
This study tests a smartphone app called Baba that helps people who live alone and feel exhausted. It aims to see if the app can make daily life easier and reduce feelings of burnout.
Baltimore, MarylandAges 65 years+ - NCT07494929Recruiting
A prevention program for pre-teens and families
This study tests a program called Mentalization-Based Prevention that helps pre-teens (ages 8–11) and their families build emotional understanding and coping skills. The goal is to strengthen well-being and prevent mental-health challenges before they start.
HeidelbergAges 8 years+ - NCT06707363Recruiting
Psychological factors and pain after orthopedic surgery
This study looks at how your thoughts and feelings affect your pain after orthopedic surgery. Researchers want to understand these factors to improve care for future patients.
Krakow, MalopolskaAges 18–65 - NCT06707935Recruiting
Mental health help-seeking for older adults
This study tests a program to help older adults find support for their mental health. It uses a smartphone app to provide information and encouragement, so you can learn how to get the help you might need.
Hong KongAges 60 years+ - NCT05699226Recruiting
Testing whether adjusting ECT treatment helps depression outcomes
This study tests a way of adjusting (titrating) ECT treatment to improve outcomes in people with major depression or bipolar II. It’s mainly for those who already need ECT with right-side electrode placement.
Albuquerque, New MexicoAges 50 years+ - NCT06986993RecruitingPhase 4
Semaglutide for smoking and weight in people with obesity
This study tests whether the medication semaglutide (similar to Ozempic/Wegovy) can help people who smoke and have obesity cut down on cigarettes, even if they aren't ready to quit. Participants will receive the drug and be monitored for changes in smoking habits and health.
Oklahoma City, OklahomaAges 18–65 - NCT06468111Recruiting
Can therapy dogs help kids during blood draws or dental work?
This study tests if having a gentle therapy dog nearby can help children ages 3 to 12 feel calmer and more comfortable during a blood draw or dental procedure. If your child likes dogs and needs one of these procedures, this might be a good fit.
LleidaAges 3–12 - NCT07681492Recruiting
Depression, aging, and antidepressants: a belief study
This trial studies how depression and antidepressants affect belief updating in older adults. You may join if you are over 65, have major depression, and are starting a new antidepressant. The goal is to learn more about how your brain adjusts beliefs over time.
RennesAges 65 years+ - NCT05671133Recruiting
Decision support to help clinicians prevent suicide risk
This study looks at whether a computer tool helps clinicians respond in a way that reduces suicidal thoughts or behaviors. If you’re attending the APS and can consent, the study may involve your information being used to improve clinician decision-making.
Boston, MassachusettsAges 18 years+ - NCT06963086Recruiting
Eating disorder prevention program for teens in Nova Scotia
This study tests a program to help prevent eating disorders in teen girls and young women in Nova Scotia. It offers both in-person groups at schools and virtual groups you can join from home.
Halifax, Nova ScotiaAges 15–22 - NCT05541926Recruiting
Scaling up e-Connect in Juvenile Probation
This trial tests a program called e-Connect that helps connect youth on probation to mental health services. It aims to see if expanding this program improves outcomes for teens and the staff who work with them.
New York, New YorkAges 10 years+ - NCT07475039Recruiting
Friendly phone calls to support older adults
This study tests whether a program of friendly phone calls from trained volunteers can help older adults feel more connected and supported. If you are 65 or older and already receive home-delivered meals or other services, you may be able to join.
Gainesville, FloridaAges 55 years+ - NCT06420544Recruiting
Japi: Brain and Social Skills Program for Preschoolers
This trial tests a program called Japi that helps preschool children improve their thinking, feelings, and social skills. It's for schools in Santiago, Chile, that serve many students with economic challenges.
Santiago, Santiago MetropolitanAges 3–5 - NCT07490600Recruiting
Testing brain stimulation and rewards for quitting cocaine
This trial combines deep transcranial magnetic stimulation (TMS) with a reward program (contingency management) to help people stop using cocaine. It may help if you are struggling with moderate to severe cocaine use and want a non-drug treatment.
Houston, TexasAges 18–65 - NCT07663812Recruiting
Motivational program for stress in pregnant couples
This study tests whether motivational techniques can help pregnant women and their partners feel less stressed and better able to express emotions. It is for couples who are in the second trimester of a low-risk pregnancy.
Yozgat, CenterAges 18 years+ - NCT07188597Recruiting
Therapy to help prevent first episode of psychosis
This trial tests a culturally adapted talking therapy to help young people who are at risk of having their first episode of psychosis. If you are between 16 and 35, have some early warning signs but no history of psychosis, this study might be a good fit.
Karachi, SindhAges 16–35 - NCT07513220Recruiting
Mindful Self-Compassion Training for Teenagers
This study tests whether learning self-compassion through mindfulness helps teenagers feel better emotionally. You'd join online group sessions for 4 weeks and answer questions about how you're feeling.
Malden, MassachusettsAges 14–19 - NCT07189104Recruiting
SAGA program for toddlers' language and social growth
This study looks at whether a program called SAGA can help toddlers in Swedish-speaking childcare in Finland with their language and social-emotional skills. It's designed for children aged 11 to 36 months.
Helsinki, UusimaaAges 11 months–3 years - NCT05880719Recruiting
Music-based computer program for memory after first psychosis
This study tests whether using a computer-based music program can help improve memory and thinking in young people who have had their first episode of psychosis. Participants will work in small groups with the program to see if it helps their cognitive skills.
CaenAges 18–30 - NCT07005817Enrolling by invitation
Social media study for young adults' health
This study looks at how social media use affects health in young adults. If you use social media, have a smartphone, and belong to certain groups with higher health risks, you may be able to join.
Chapel Hill, North CarolinaAges 18–29 - NCT07658326Recruiting
Stress and rotator cuff surgery study
This study looks at how stress before surgery might affect recovery in people having rotator cuff surgery. You may be able to join if this is your first surgery for a torn rotator cuff and you don't have certain other health problems.
CornebarrieuAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Blood & lymphatic
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.