Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,764 recruiting studies in this area right now.
By phase
- Not applicable6,413
- Phase 2492
- Phase 1247
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder140
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York254
- Texas209
- Maryland175
- Pennsylvania169
- Florida147
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,764 total
- NCT07497698Recruiting
Saffron supplement for better sleep in adults
This study tests whether taking a saffron extract supplement can help improve sleep in middle-aged adults with mild to moderate sleep troubles. You would take a daily supplement for a few weeks and report how well you sleep.
Granada, GranadaAges 18–65 - NCT07490717Enrolling by invitation
Treating PTSD and opioid use in jails
This study tests new ways to screen and treat people in jail who have both post-traumatic stress disorder (PTSD) and opioid use disorder. It aims to help participants with therapy while incarcerated and after release.
Little Rock, ArkansasAges 18 years+ - NCT07494110Recruiting
Aurora: AI storytelling for emotional wellbeing
This study tests a guided, AI-based storytelling tool to help people process their experiences and feel better emotionally. Depending on who you are, the session lasts 1 to 4 hours.
Barcelona, BarcelonaAges 18 years+ - NCT07496918RecruitingPhase 2
Brain effects of light and sound stimulation at 40 Hz
This study tests whether special lights and sounds (at a specific 'gamma' frequency) can safely affect brain activity. It is an early trial looking at how the brain responds to these gentle sensory stimulations.
Cambridge, MassachusettsAges 18–100 - NCT07493317RecruitingPhase 2
Tocilizumab for depression with inflammation
This trial tests a medication called tocilizumab, which targets inflammation, to see if it can improve symptoms of major depression in people with signs of inflammation. You may be eligible if you have depression with a high monocyte count and significant loss of interest or pleasure.
New York, New YorkAges 18–70 - NCT07497347Recruiting
Amino acids and lifestyle for brain aging in older adults
This study tests whether taking a specific amino acid supplement, along with lifestyle changes, can help slow or improve brain aging in older adults who have mild depression. It aims to see if these nutrients can support brain health and mood.
BresciaAges 65–85 - NCT07492472Recruiting
Low-intensity music for anxiety in young adults
This trial tests whether listening to low-intensity music can help ease anxiety in young adults. If you join, you will answer some questions about your symptoms while the study also measures things like your voice, heart rate, and brain activity.
Haikou, HainanAges 18–25 - NCT07494786Recruiting
Parenting chatbot for Palestinian refugees in Jordan
This study tests a parenting chatbot designed to support parents in stressful situations like war and displacement. If you join, you may receive the chatbot right away or after a waiting period.
JerashAges 18 years+ - NCT07490379Recruiting
Home vs. Hospital Brain Stimulation for Depression
This trial compares doing transcranial direct current stimulation (tDCS) at home versus in the hospital to see if it works as well for depression. tDCS uses a mild electrical current on the scalp to help improve mood.
AngletAges 18 years+ - NCT07491627Enrolling by invitation
Nicotine's effect on gum disease treatment in smokers and non-smokers
This study looks at how smoking and nicotine affect the success of gum disease treatment. It compares results between smokers and non-smokers who have gum disease.
Liège, LiegeAges 18 years+ - NCT07497763Recruiting
Support program to help prevent return hospital stays
This study tests a short support program for people who were recently admitted to a psychiatric hospital against their will. The program helps them recover personally and aims to reduce the chance of being admitted again involuntarily.
Lausanne, Canton of VaudAges 18–64 - NCT07495189Enrolling by invitation
Mood, sleep, and brain study
This trial looks at how mood problems and sleep issues affect each other. It compares people with and without these conditions to understand the connection.
Jinan, ShandongAges 18–80 - NCT07495761Recruiting
Central sensitization signs in adults with autism
This study looks at whether adults with autism (without intellectual disability) experience central sensitization, a condition where the nervous system becomes overly sensitive to stimuli. It aims to understand how common this is and why it matters for treatment.
Grenoble, IsereAges 18 years+ - NCT07495917Recruiting
Tetris game for reducing intrusive memories
This study tests whether playing Tetris after a brief memory reminder can help reduce the number of intrusive memories you experience after a traumatic event. It might help your brain process the memory in a way that makes it less intrusive.
Xi'an, ShaanxiAges 18–50 - NCT07498283Recruiting
Peer mentor support for atrial fibrillation
This study tests if having a peer mentor—someone who has been through similar health experiences—can help people with atrial fibrillation who have lower income or education levels. You would talk with a mentor and fill out surveys to see if this support improves your well-being.
Herlev, Capital RegionAges 18 years+ - NCT07494955Recruiting
Mindful breathing before spinal for C-section
This trial tests if a short breathing exercise before spinal anesthesia can help keep your blood pressure steady during a planned C-section. You will practice the technique briefly before the procedure.
ErzurumAges 18–45 - NCT07491549Recruiting
Pain education group therapy for chronic pain
This trial tests if group education about pain can help people with chronic pain move more, feel better, and have less fear of movement. It's looking for adults whose pain has lasted more than 3 months and affects their daily life.
Tartu, TartuAges 16–65 - NCT07498452Recruiting
Sleep behavior study for patients and their partners
This study looks at the needs of people with isolated REM sleep behavior disorder (iRBD) and the people close to them. It aims to understand how this condition affects daily life and relationships.
Bologna, Emilia-RomagnaAges Any age - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT07494929Recruiting
A prevention program for pre-teens and families
This study tests a program called Mentalization-Based Prevention that helps pre-teens (ages 8–11) and their families build emotional understanding and coping skills. The goal is to strengthen well-being and prevent mental-health challenges before they start.
HeidelbergAges 8 years+ - NCT07496021Recruiting
Probiotic for early Alzheimer's: safety and memory benefits
This trial tests a new probiotic (Lactococcus lactis CKDB001) to see if it can slow memory loss in people with early Alzheimer's. It’s a 12-week study that requires a positive amyloid PET scan and allows mild to moderate symptoms.
Gyeonggi-doAges 55–85 - NCT07489651RecruitingPhase 2
New treatment for generalized anxiety disorder
This trial tests a new medication called RE104 for people with generalized anxiety disorder (GAD). The goal is to see if it helps reduce anxiety symptoms safely.
Birmingham, AlabamaAges 18–74 - NCT07494305RecruitingPhase 2
Testing a new drug for bipolar depression
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
Bentonville, ArkansasAges 18–65 - NCT07493265RecruitingPhase 2
Study of E2086 for adults with narcolepsy
This study tests a new drug called E2086 to see if it can help reduce daytime sleepiness and sudden muscle weakness in adults with narcolepsy. It involves two groups: people with cataplexy (type 1) and those without (type 2).
Santa Ana, CaliforniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,764 recruiting psychiatry studies from the U.S. registry right now, out of 12,350 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.