Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,764 recruiting studies in this area right now.
By phase
- Not applicable6,413
- Phase 2492
- Phase 1247
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder140
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York254
- Texas209
- Maryland175
- Pennsylvania169
- Florida147
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,764 total
- NCT07487818RecruitingPhase 2/Phase 3
Vagus nerve stimulation with nicotine replacement for quitting smoking
This study tests whether adding a gentle nerve stimulation device to nicotine replacement therapy (like patches or gum) can help people quit smoking more effectively. It may be a new option for those who have struggled to quit before.
Rochester, MinnesotaAges 18 years+ - NCT07485725Recruiting
Digital tools study for health decisions
This study tests if digital tools can help older adults make better healthcare decisions. You’ll use a website to search for health information and share your thoughts in interviews.
Tallahassee, FloridaAges 60 years+ - NCT07489443Recruiting
Helping pregnant women reduce tobacco and cannabis use
This study is testing a program to help pregnant women and new mothers cut back on or quit using tobacco and cannabis. It’s designed to see if the program is easy to use and helps improve health for both mom and baby.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06776328Recruiting
Co-creating tools for youth with suicidal thoughts
This study aims to develop tools together with children and teenagers who have had suicidal thoughts. The goal is to create better support options for young people.
GhentAges 10–18 - NCT06777186Recruiting
Motor skills and balance study for autism
This study looks at motor skills, balance, and social adaptation in children with autism. It aims to understand how these areas are connected and could help improve therapies.
Kirikkale, KırıkkaleAges 4–21 - NCT04668560Recruiting
Testing a “5 Ways to Wellbeing” course for health support
This trial studies whether a structured “5 Ways to Wellbeing” course can help people make healthier choices and cope better with health problems or long-term (chronic) illness. It may be especially relevant if you’re currently off work due to health concerns or receiving support payments.
OsloAges 18 years+ - NCT06133231Recruiting
ADHD research with Black and Hispanic families
This study tests if a new approach to ADHD research works well with diverse families. It involves taking supplements and collecting samples at home to see how the body responds.
Portland, OregonAges 6–17 - NCT06636357RecruitingPhase 2
Laughing gas for acute suicidal thoughts
This study tests whether breathing a mixture of nitrous oxide (laughing gas) and oxygen can quickly reduce strong suicidal thoughts. It's for people experiencing a mental health crisis who may need fast relief.
ZurichAges 18–65 - NCT06777563Recruiting
Mood app and check-ins to prevent postpartum depression
This study tests whether using a smartphone program (mHealth) along with emotional support (EMA) can help prevent postpartum depression in pregnant women who are feeling distressed. It is for women in Hong Kong who are at 20–28 weeks of pregnancy and have mild to moderate mood symptoms.
Hong Kong, PokfulamAges 18 years+ - NCT06781203Recruiting
Finding the best sleep treatment for insomnia
This study compares different parts of sleep therapy to see which works best for people with moderate-to-severe insomnia. If you have trouble sleeping and are referred by your doctor, you may be able to join.
AarhusAges 18 years+ - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+ - NCT06179953Recruiting
Emotional skills training with a social robot
This trial tests whether a social robot can help children improve their emotional and communication skills. It is designed for children who can speak in sentences and connect ideas to talk about events.
Messina, ItalyAges 5–10 - NCT07478744RecruitingPhase 2
Study for generalized anxiety disorder with SYT-510
This trial tests a new medicine called SYT-510 for adults with generalized anxiety disorder who are not currently taking medication. It aims to see if the drug reduces anxiety and is safe.
LondonAges 18–55 - NCT07477990RecruitingPhase 3
Testing a digital device for anxiety treatment
This trial is testing a digital device called Aurora that helps treat moderate to severe anxiety. It compares the device to standard anxiety medications, so you may receive either the device or a pill. The goal is to see if the device can work as well as medication without the side effects.
Mexico City, Mexico CityAges 18–65 - NCT07477470Recruiting
Fiber supplement for stress and mood
This study tests whether a daily fiber supplement can improve mood, memory, and gut health in stressed adults. It lasts a few weeks and involves questionnaires and samples.
LondonAges 18–50 - NCT07472998Recruiting
Heart rate changes in people with a specific dizziness condition
This study looks at heart rate differences in people who have brief episodes of spinning dizziness (BPPV) compared to healthy people. It aims to see if the dizziness affects how the heart responds.
Istanbul, KüçükçekmeceAges 18–65 - NCT07477431RecruitingPhase 2
Testing levetiracetam for those at risk of Alzheimer's
This trial tests if a medication called levetiracetam (a drug usually used for seizures) can help protect memory in people who are at higher risk for Alzheimer's but do not yet have memory problems. It involves brain scans and cognitive tests to see if the drug can reduce overactive brain activity linked to memory loss.
Toronto, OntarioAges 55–85 - NCT07477899Enrolling by invitation
Growing up in challenging early life conditions
This study looks at how things like family or environmental challenges affect growing up. The goal is to understand the impact and find ways to support adults.
Bosisio Parini, LCAges 18 years+ - NCT07480590Recruiting
Gender-Affirming Care and Mental Health Study
This study follows adults who are referred to a gender dysphoria assessment clinic in southern Sweden to see how gender-affirming care affects quality of life, work life, and overall health over time.
Malmö, MalmöAges 18 years+ - NCT07477873Enrolling by invitation
Emotions and jaw surgery recovery study
This study looks at how patients feel emotionally and physically before and after jaw surgery. It uses special software and questionnaires to track emotions, and checks the jaw joint and muscles after surgery. The goal is to see how these relate to recovery in patients having planned jaw surgery.
Kaunas, KaunoAges 18 years+ - NCT07478796RecruitingPhase 4
Blood-based dosing of SSRIs for hospitalized depression
This study tests whether adjusting the dose of common antidepressants (SSRIs) based on regular blood tests can help people in the hospital feel better faster. It is for adults and teens age 12 and older with moderate to severe depression who are starting fluoxetine, escitalopram, or sertraline.
Poznan, Greater Poland VoivodeshipAges 12 years+ - NCT07480525Recruiting
Escitalopram for first-time depression
This trial tests whether escitalopram, a common antidepressant, helps people who are experiencing their first episode of depression and have never taken medication for it. It also looks at how the drug works in the brain.
Beijing, Beijing MunicipalityAges 18–65 - NCT07476222Recruiting
Predicting testosterone decline in middle-aged men
This study looks at why testosterone levels drop in men aged 35-59. It may help identify early signs and ways to prevent it.
AndijanAges 35–59 - NCT07474363Recruiting
Depression differences between men and women
This study looks at how depression affects men and women differently, including symptoms, strength to cope (resilience), and feelings of stigma. It aims to understand these differences to improve treatment.
Eskişehir, EskişehirAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,764 recruiting psychiatry studies from the U.S. registry right now, out of 12,350 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.