Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT06870955Recruiting
Study of biomimetic abutments for dental implants
This trial tests a new type of abutment (the connector piece between an implant and a crown) that is designed to look and function more like a natural tooth root. It may help people who have a single missing tooth and need a second surgery to uncover their implant.
Fuzhou, FujianAges 25–65 - NCT06870435Recruiting
Screening for nasopharyngeal cancer with blood tests
This study compares three different blood tests to see which works best for spotting nasopharyngeal cancer early in people at higher risk. If you live in certain areas of China, you may be able to join.
Zhuhai, GuangdongAges 30–69 - NCT07318298Recruiting
Hyaluronic acid injection for wisdom tooth socket healing
This trial tests if injecting hyaluronic acid into the sockets after wisdom tooth removal helps bone heal faster. It may be an option if you need both lower wisdom teeth removed and are generally healthy.
IrbidAges 18–35 - NCT07317570Recruiting
Body awareness therapy for jaw pain and function
This study tests whether body awareness therapy (gentle exercises that help you notice how your body moves and feels) can reduce jaw pain, improve function, and help with related emotional stress. It is for people with long-term jaw joint problems.
RizeAges 18 years+ - NCT07316582Enrolling by invitationPhase 4
Melatonin gel for gum disease treatment
This trial tests a new gel made with melatonin and platelet-rich fibrin to treat gum disease. It may help reduce pocket depth and improve gum health without surgery.
New CairoAges 20–60 - NCT07320417Recruiting
Preserving sinus lining during maxillary surgery
This study tests a modified surgery technique that keeps the sinus membrane intact while removing part of the upper jaw. It aims to reduce complications and help bone healing for patients with growths in the upper jaw that haven't spread to the sinus cavity.
ShanxiAges 18–75 - NCT07315620Recruiting
Dental implant bridge fit using digital methods
This study tests if a fully digital workflow can make dental implant-supported bridges fit better and more comfortably. It may help people who need a full set of implant teeth on the upper or lower jaw.
Madrid, MadridAges 18 years+ - NCT07320924Recruiting
Custom Plate for Lower Jaw Bone Defects
This trial tests a custom-made metal plate designed to replace a missing piece of your lower jaw bone. It may be a good option if you have a gap in your jaw from a tumor, infection, or injury, as long as the joint near your ear is not involved.
Alexandria, Alexandria GovernorateAges Any age - NCT07317596Enrolling by invitationPhase 3
Comparing two treatments to reduce pain after wisdom tooth surgery
This trial compares two treatments, methylprednisolone and hyaluronic acid, given during wisdom tooth removal to see which one helps reduce pain and swelling afterward. You may participate if you need a special type of impacted wisdom tooth removed and are generally healthy.
SanaaAges 18–40 - NCT07324525Recruiting
Oral health study for people in palliative care
This survey study explores oral health in people receiving palliative care. By answering a questionnaire, you can help improve care and comfort for patients with serious illness.
Göttingen, GermanyAges 18 years+ - NCT07321483Recruiting
Reflex therapy for jaw pain
This trial tests if a special reflex therapy can help people with jaw muscle pain that isn't caused by joint damage. It might be a new way to reduce discomfort and improve function.
OlomoucAges 18 years+ - NCT07316023RecruitingPhase 2
Light therapy for gum disease treatment
This trial tests a new light treatment for gum disease using a special dye that targets and kills harmful bacteria. It may help if you have advanced gum disease and haven't had treatment recently.
CairoAges 36–50 - NCT05927688Recruiting
Using patient reports to adjust treatment for autoimmune diseases
This study looks at whether doctors consider patient “electronic reports” (completed online/phone) when deciding how often to change treatment. It may help improve how well treatment plans match how patients feel over time.
StrasbourgAges 18 years+ - NCT06514677Recruiting
Nonsurgical treatment for implant infection with ultrasonic carbon tip
This study tests whether using a special ultrasonic carbon tip (a gentle cleaning tool) can treat infection around a dental implant without surgery. It is for people with a single problem implant who are otherwise healthy and have good oral hygiene.
KütahyaAges 18–99 - NCT05825170Recruiting
Hyaluronic acid lip filler for lip deformity after cleft surgery
This trial tests a hyaluronic acid filler (placed in the lips) to improve lip shape in people who had cleft lip and palate surgery. It looks at how well the filler works and how safe it is for your lips and surrounding skin.
Lille, NordAges 18 years+ - NCT06030947Recruiting
Micro graft for treating multiple gum recessions
This trial tests a new micro connective tissue graft to cover multiple areas where your gums have pulled away from your teeth (recession). It may help if you have healthy gums but several receding spots on your upper or lower jaw.
DubaiAges 18–60 - NCT06186830Recruiting
Questionnaire for jaw and face pain
This study tests a special questionnaire (BETY-BQ) to see how well it measures the impact of jaw and face pain in people with temporomandibular disorders. It helps doctors better understand your symptoms and guide treatment.
Karabük, Karabük ProvinceAges 18–64 - NCT07314580Recruiting
Transplanting premolars to replace lost front teeth in teens
This trial tests whether moving a back tooth (premolar) to replace a lost or damaged front tooth works well in young people aged 7–15. It aims to help avoid bridges or implants by using the patient's own tooth.
Barcelona, BarcelonsAges 7–15 - NCT07309653Recruiting
A new single-shade filling for broken front teeth in kids
This study is testing a new single-shade filling material for broken front teeth in children. We want to see if the color matches well, stays strong, and makes kids and parents happy with the look.
BangkokAges 6–15 - NCT07309588Enrolling by invitationPhase 1/Phase 2
Hyaluronic acid gel for dry mouth
This trial tests if a gel made from hyaluronic acid (a natural substance that holds moisture) can help people with long-term dry mouth. It aims to make eating, speaking, and sleeping easier.
Poznan, Greater Poland VoivodeshipAges 38–78 - NCT07311772RecruitingPhase 3
Testing houyanqing liquid for mouth sores during radiation
This trial tests a liquid medicine (houyanqing) to prevent or treat mouth sores caused by radiation therapy for nasopharyngeal cancer. You swish it in your mouth during radiation to see if it helps reduce pain and healing time.
Beijing, Beijing MunicipalityAges 18–75 - NCT07312045Recruiting
Gum health and healing after non-surgical treatment
This study looks at how certain blood and saliva measurements relate to gum disease and healing after a deep cleaning. It may help find better ways to track gum health.
Merkez, ErzincanAges 18–65 - NCT07306533Recruiting
Menstrual phase and dental pain relief study
This trial tests whether the phase of your menstrual cycle affects how well local anesthesia works for a root canal. It may help dentists give you better pain control based on your cycle.
New Delhi, Delhi(दिल्ली)Ages 18–45 - NCT07315607Recruiting
Study of same-day implant crowns made with digital planning
This trial tests a new digital planning and guided surgery method for placing and placing a temporary crown on a dental implant right after tooth removal. It aims to see how accurate these same-day, screw-retained crowns are, which could mean fewer visits and faster results for you.
Madrid, MadridAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.