Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07314034Recruiting
Digital full-mouth dental restoration trial
This trial tests a fully digital, face-guided approach to replace missing teeth and fix bite or cosmetic issues. It may help if you need a complete mouth rebuild and are open to a modern digital treatment process.
Shibīn al Kawm, MenoufiaAges 20–45 - NCT07312552Recruiting
Gum health, smoking, and saliva markers study
This study looks at how gum health and smoking affect certain proteins in your saliva. It may help researchers understand more about gum disease and inflammation.
IstanbulAges 18–65 - NCT07315607Recruiting
Study of same-day implant crowns made with digital planning
This trial tests a new digital planning and guided surgery method for placing and placing a temporary crown on a dental implant right after tooth removal. It aims to see how accurate these same-day, screw-retained crowns are, which could mean fewer visits and faster results for you.
Madrid, MadridAges 18 years+ - NCT07314580Recruiting
Transplanting premolars to replace lost front teeth in teens
This trial tests whether moving a back tooth (premolar) to replace a lost or damaged front tooth works well in young people aged 7–15. It aims to help avoid bridges or implants by using the patient's own tooth.
Barcelona, BarcelonsAges 7–15 - NCT07306533Recruiting
Menstrual phase and dental pain relief study
This trial tests whether the phase of your menstrual cycle affects how well local anesthesia works for a root canal. It may help dentists give you better pain control based on your cycle.
New Delhi, Delhi(दिल्ली)Ages 18–45 - NCT07310979Enrolling by invitation
Study of a special dental implant design
This trial tests a new shape for a dental implant that holds three teeth. It may help people who need a strong, stable replacement for missing teeth.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07306117Enrolling by invitation
Digital oral health study for teens with gingivitis
This study tests a new digital tool to help teenagers with gum inflammation improve their oral health. It focuses on 16-17 year olds who have plaque on at least half of their teeth.
GothenburgAges 16–17 - NCT07302581Recruiting
Study of dental implants with natural ligament for single tooth replacement
This trial tests a new type of dental implant that includes a ligament (like a natural tooth's shock absorber). It's for people who need to have a single front or side tooth pulled and have healthy gum and bone around the area. The goal is to see if this implant works well and stays healthy over time.
Kōriyama, FukushimaAges 18 years+ - NCT06457737Recruiting
Comparing two bonding methods for back tooth crowns
This study compares two different ways of bonding tooth-colored crowns on back teeth to see which one lasts better. If you need a back tooth restored, you may be able to join.
IrbidAges 18 years+ - NCT07301918Recruiting
Comparing two expanders for crossbite in children
This trial compares two types of expanders (Leaf Expander vs. Hyrax Expander) to fix crossbites in children who still have some baby teeth. The goal is to see which device works better and is more comfortable.
CairoAges 6–12 - NCT07301892Recruiting
AI help for rheumatoid arthritis diagnosis
This trial tests whether artificial intelligence (AI) can improve how doctors spot complications in people newly diagnosed with rheumatoid arthritis (RA), a condition that causes joint pain and swelling. The goal is to see if AI can make diagnosis faster and more accurate in real-world hospital settings.
Beijing, Beijing MunicipalityAges Any age - NCT07303023RecruitingPhase 3
Personalized neck radiation to prevent cancer spread
This trial tests whether a personalized radiation plan for the neck can prevent cancer from spreading in people with nasopharyngeal carcinoma. It's for those whose cancer hasn't spread beyond the head and neck area.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+ - NCT07303530Recruiting
Effect of printing layer thickness on fungus growth in 3D-printed dentures
This trial tests how the thickness of printing layers in 3D-printed dentures affects the growth of Candida albicans, a type of fungus that can cause infections. It aims to find the best design to keep your mouth healthier.
Cairo, Cairo GovernorateAges Any age - NCT07304752Recruiting
Probe Material Effect on Implant Gums Measurement
This study compares how different materials used for probing around dental implants affect accuracy. It is for people with a single implant (with a screw-retained crown, no abutment) that has been in use for at least a year and is either healthy or has only mild gum inflammation.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07301164RecruitingEarly Phase 1
BCT301 cell therapy for hard-to-treat autoimmune diseases
This trial tests a new cell treatment called BCT301 for people with certain autoimmune diseases like lupus or scleroderma that haven't gotten better with standard medicines. It aims to see if this treatment can help control the disease.
BeijingAges 18–80 - NCT07306026Recruiting
Testing a toothbrush's bristles on plaque and gums
This trial compares how well different toothbrush bristles remove plaque and affect gum health. It may help find the best toothbrush design for everyday oral care.
Buffalo, New YorkAges 18–70 - NCT07298057RecruitingEarly Phase 1
Dental implant study for people with diabetes
This study tests if adding an antibiotic (Arestin) to standard gum cleaning can improve gum health and blood sugar control in people with type 2 diabetes.
Cleveland, OhioAges 18 years+ - NCT07304596Recruiting
Oral health impact questionnaire for periodontitis patients
This study evaluates a Hindi questionnaire that measures how periodontitis affects your daily life. It is designed for patients with periodontitis who can fill out forms on their own.
Rohtak, HaryanaAges 18 years+ - NCT07297836Recruiting
Dentist practices for treating baby teeth in France
This study surveys dentists in France about how they treat non-vital (nerve-damaged) baby teeth. It aims to understand current professional practices.
StrasbourgAges 18 years+ - NCT06238076Recruiting
Universal surgical device for jaw reconstruction
This trial tests a universal surgical device for rebuilding the lower jaw using a bone flap from the leg. It aims to make the procedure more reliable and easier for patients needing reconstruction of the front part of the jaw.
ToulouseAges 18 years+ - NCT07295197Recruiting
Oral signs for early eating disorder screening
This study looks at signs in your mouth that might help detect eating disorders early. Dentists will examine your teeth, gums, and oral tissues to see if they can spot clues that could lead to faster diagnosis and care.
BolognaAges 18–40 - NCT07296250Recruiting
Tracking cancer cells after chemoradiation for oral cancer
This trial studies whether detecting circulating tumor cells in the blood after chemoradiation can help predict outcomes for people with oral cancer that has spread to lymph nodes. It may help doctors better monitor the disease.
Taoyuan CityAges 1.5 years–90 years - NCT07290621RecruitingPhase 2
Toripalimab with standard treatment for HPV-positive throat cancer
This study tests adding a new immunotherapy drug (toripalimab) to standard chemo for HPV-positive throat cancer. It aims to see if this combination works better than chemo alone for patients whose cancer has spread to nodes but not to other parts of the body.
Chicago, IllinoisAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.