Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07326345Recruiting
Study comparing ways to widen the upper jaw
This trial tests different methods to widen a narrow upper jaw and see how they affect the nose and face bones. It is for people 15 and older who have a crossbite (when upper teeth sit inside lower teeth).
Istanbul, FatihAges 15 years+ - NCT07330089Recruiting
Sealant study: pit and fissure sealing for kids
This trial will see if dental sealants work better on healthy teeth versus those with early signs of decay. If you have a child between 7 and 18 with fully grown back molars that have no fillings, they may be able to join.
Islamabad, FederalAges 7–18 - NCT07325747Recruiting
Immediate vs. delayed surgery for infected dental implants
This study compares getting surgery right away versus waiting for infected dental implants. If you have a failing implant with bone loss around it, this trial may help decide the best time to fix it.
Ann Arbor, MichiganAges 18 years+ - NCT07325604Recruiting
Electrical stimulation for facial weakness after stroke
This trial tests whether a gentle electrical stimulation (called NMES) can help people with facial weakness after a first stroke. You would do facial exercises during the stimulation to see if it helps you regain movement.
HammelAges 18 years+ - NCT07331207Recruiting
3D-printed expander for narrow upper jaw in young adults
This study tests a new 3D-printed expander that attaches to bone to widen a narrow upper jaw in young adults. It may help if you have a crossbite or need more room in your upper jaw.
Al MansurahAges 18–30 - NCT07325643Recruiting
Toothpaste and mouthwash to prevent white spots during braces
This study tests if a special toothpaste and mouthwash can stop white spots from forming on teeth while you have braces. It is for people starting orthodontic treatment who have healthy teeth and gums.
BaghdadAges Any age - NCT07331935Recruiting
Topical Coenzyme Q10 and Curcumin for Oral Leukoplakia
This study tests whether a cream containing coenzyme Q10 and curcumin can help treat a common mouth condition called oral leukoplakia (a white patch that can sometimes turn into cancer). It is for people with a specific type of white patch that is not severe and can be easily reached with a cream.
AlexandriaAges 40 years+ - NCT07326358Recruiting
AI help for doctors finding problems in nose and throat exams
This study uses artificial intelligence to help doctors better see and find issues during nose and throat camera exams. If you are getting this exam and agree to participate, your images may be checked by the AI system to see if it can improve detection.
ShanghaiAges 18 years+ - NCT07325539RecruitingPhase 2
Radiation and immunotherapy with chemo for nose and throat cancer
This trial tests combining low-dose radiation with an immunotherapy drug (toripalimab) and chemotherapy for people whose nose and throat cancer has come back or spread. The goal is to see if this combination works better than standard treatments.
Guangzhou, GuangdongAges 18–65 - NCT07327658Recruiting
Periodontal treatment and pocket depth changes
This trial looks at how much gum pocket depth decreases after standard gum disease treatment. It is for people with advanced periodontitis who are otherwise healthy.
Konya, KonyaAges 18–65 - NCT07328269Recruiting
Mulligan vs Maitland technique for jaw pain relief
This trial compares two manual therapy methods (Mulligan and Maitland) to improve jaw movement and reduce pain in people with temporomandibular joint (TMJ) dysfunction. If you have limited jaw opening or jaw pain, you may be able to join.
Islamabad, Punjab ProvinceAges 19–44 - NCT07332247RecruitingPhase 2
Immunotherapy plus chemo then immediate vs selective re-radiation for advanced recurrent NPC
This trial is for people with nasopharyngeal cancer that has come back in the same area. It tests whether giving additional radiation right after chemo plus immunotherapy works better than waiting to see if more radiation is needed later.
Guangzhou, GuangdongAges 18–70 - NCT07327060Recruiting
Camera-Assisted Parent Training for Children's Teeth
This study tests whether teaching parents with a small intraoral camera can help improve their child's toothbrushing habits. It focuses on children ages 5–7 who have a new permanent molar coming in.
AydinAges 5–7 - NCT07330609Recruiting
Gum and bone graft study for dental implants
This trial tests whether using a small piece of tissue from your own body can improve the gum around dental implants. It might help if you have thin or narrow gum tissue.
Kütahya, MerkezAges 1.5 years+ - NCT07327216RecruitingPhase 3
Comparing two inhalations for mouth sores from cancer treatment
This trial tests if an inhaled medication called Sapylin can prevent or reduce severe mouth sores caused by chemoradiation, compared to a standard steroid inhalation. It is for people with advanced nasopharyngeal cancer who have not yet started treatment.
Zhanjiang, GuangdongAges 18–75 - NCT07330570Recruiting
Caries risk after dental surgery under general anesthesia
This study looks at how likely children are to get new cavities after they have had dental treatment under general anesthesia for early childhood cavities. It aims to help dentists better understand and prevent future decay.
Aydin, AydınAges 6–16 - NCT07327333Enrolling by invitation
AR education for nurses on oral mucositis care
This trial tests if an augmented reality (AR) learning tool helps nurses better care for patients with oral mucositis, a painful side effect of cancer treatment. It is designed for cancer nurses at a hospital in northern Taiwan.
TaipeiAges 20 years+ - NCT07328854RecruitingPhase 3
Lower versus standard radiation in stage II nasopharyngeal cancer
This trial compares a lower dose of radiation (40.2 Gy) to the standard dose (49.2 Gy) for patients with stage II nasopharyngeal carcinoma that has shrunk after initial chemoimmunotherapy. The goal is to see if the lower dose works just as well while potentially causing fewer side effects.
Hefei, AnhuiAges 18–75 - NCT07330154Recruiting
Gel for Faster Healing After Gum Graft Surgery
This trial tests a new gel (Nano Bio Fusion Gingival Gel) to see if it helps the roof of your mouth heal faster after a gum graft. It compares the gel to a placebo (inactive gel). The study is for people who need gum graft surgery for receding gums.
Irbid, Irbid GovernorateAges 18 years+ - NCT07333534Recruiting
Bone graft with or without gum graft for front tooth implants
This study compares two ways to rebuild bone and gum around a dental implant placed immediately after removing a failing front tooth. It may help patients who need a tooth replaced in the smile zone and have enough healthy bone to support the implant.
Baghdad, RusafaAges 18–65 - NCT07328841RecruitingPhase 3
Lower radiation dose study for advanced nasopharyngeal cancer
This trial compares a lower dose of radiation to the standard dose for people with advanced nasopharyngeal cancer that shrank after chemotherapy and immunotherapy. The goal is to see if a lower dose works just as well with fewer side effects.
Guangzhou, GuangdongAges 18–70 - NCT05604391Recruiting
Free gum graft to help cover exposed tooth roots
This trial studies a procedure called a free gingival graft to cover exposed (receding) tooth roots and improve comfort and appearance. You might benefit if you have gum recession in the front lower teeth and meet the specific dental and health requirements.
KütahyaAges 18–99 - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT06692244Recruiting
Custom 3D-printed mesh for jawbone regrowth
This trial is testing a custom-made titanium mesh (built with a 3D printer) to help regrow bone in your jaw where teeth are missing. It may be an option if you have moderate to severe bone loss and need a strong foundation for dental implants.
Guangzhou, GuangdongAges 18–60
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Genetic & congenital
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.