Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,057 recruiting studies in this area right now.
By phase
- Not applicable1,634
- Phase 2148
- Phase 183
- Phase 381
- Phase 459
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma80
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Oral Cancer35
- Head and Neck Cancer34
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University52
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California39
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,057 total
- NCT06884787Recruiting
New tooth-colored filling for front teeth: how well does it work?
This trial is testing a modern tooth-colored filling material for fixing cavities or gaps in front teeth. It looks at how well the filling performs and how satisfied patients are. You might be eligible if you need fillings in at least two front teeth and have generally healthy teeth and gums.
IrbidAges 18 years+ - NCT06825273Recruiting
3D-printed space maintainer for lost baby molars
This study tests a 3D-printed space maintainer (like a small partial denture) for children who have lost a lower baby molar early. It helps keep space for the permanent tooth to come in properly.
TantaAges 7–9 - NCT06888947Enrolling by invitation
Collagen cone for dental implants placed right after tooth removal
This study tests whether placing a collagen cone around a new dental implant helps it heal better when the implant is put in right after a tooth is pulled. It focuses on front teeth and premolars in the upper jaw.
CairoAges 30–50 - NCT06866431Recruiting
Ultrasound cavitation for faster healing after tooth extraction
This study tests if a special ultrasound tool (called cavitation) can help your gums heal better after having two teeth pulled. It is for people who need two teeth removed from the same jaw.
Trieste, TSAges 18–100 - NCT06819995Recruiting
3D-printed vs milled guides for dental implants
This study compares two types of surgical guides used to place dental implants: one made with a 3D printer and one milled from a solid block. If you're missing one to four teeth and have healthy healed gums and bone, this trial may help determine which guide works best.
MadridAges 21 years+ - NCT06842368Recruiting
Immediate implants with vitamin D or hyaluronic acid bone graft
This study compares two types of bone graft materials mixed with either vitamin D or hyaluronic acid for dental implants placed immediately after a tooth is removed. It aims to see which helps the implant heal better.
CairoAges 18–60 - NCT06757218Recruiting
Preserving jawbone after tooth extraction with dentin and platelet gels
This study tests two types of platelet-rich fibrin gels (one with albumin) mixed with your own tooth dentin to help preserve the jawbone after a tooth is pulled. It may reduce bone loss and improve healing for those needing a future dental implant.
Kafr ash Shaykh, KafrelsheikhAges 18–60 - NCT06762821Recruiting
Single vs multiple visit root canal for immature teeth
This study compares doing root canal treatment in one visit versus multiple visits for children with an immature front tooth that has died (the nerve is damaged). It aims to see which approach helps the tooth heal better over 24 months.
MinyaAges 7–13 - NCT06745232Recruiting
New 3D camera system for full mouth dental impressions
This trial tests a new 3D camera system to capture impressions for dental implants. It may help you if you need full mouth implants and have good bone and gum health.
Roma, RMAges Any age - NCT06709183Enrolling by invitation
Mouth care tool for patients on breathing tubes
This study tests a new mouth care device for patients who are on breathing tubes. It asks nurses to help improve oral care in the ICU.
Bitlis, MerkezAges 18 years+ - NCT07111455Recruiting
Oral bacteria changes with chemoimmunotherapy for mouth cancer
This study is testing whether a combination of chemotherapy and immunotherapy before surgery can help treat advanced oral cancer. Researchers will also look at how the cancer changes the bacteria in your mouth.
Guangzhou, GuangdongAges 18–80 - NCT06760442Recruiting
Dental implant placement: even with the bone vs slightly below
This trial compares two ways of placing a dental implant in the jawbone to see which leads to less bone loss around the implant. It may help if you are missing a back tooth and have enough jawbone after a bone graft.
CairoAges 21–60 - NCT06725979Recruiting
Palatal expansion for sleep disorders in children
This trial tests if a treatment that widens the upper jaw (palatal expansion) can improve sleep problems in children who have a narrow upper jaw.
Rijeka, Primorje-Gorski Kotar CountyAges 2–18 - NCT06665451Recruiting
Erythropoietin gel for better dental implant stability
This trial tests whether applying a special gel containing erythropoietin (a protein that helps healing) around a dental implant can improve how well the implant holds in the bone. It may help people who need a front tooth replaced after extraction.
Asyut, Asyut GovernorateAges 20–50 - NCT06643975Recruiting
Comparing tooth implants for lower jaw overdentures
This study compares patient satisfaction and bone changes around two types of dental implants used to support a removable lower denture. It may help you understand which implant material works best for you.
CairoAges 50–60 - NCT06695208RecruitingPhase 4
Bone graft options to save socket after tooth extraction
This trial tests two materials, Biodentin and a xenograft, to see which one better preserves the bone socket after a single-rooted tooth is pulled. It may help you if you need a tooth extracted and plan to get a dental implant later.
GizaAges 25–50 - NCT06645860Recruiting
Smart treatment for painless cavities in baby teeth
This study tests a special treatment (SMART) for cavities in baby teeth that don’t hurt. It uses different materials to fix the holes, and may help avoid more complex procedures.
Çanakkale, KepezAges 4–9 - NCT06671743RecruitingPhase 3
Medication before root canal to reduce pain
This study tests whether taking a medication before a root canal can reduce pain afterward. It is for people who need a root canal on a lower back tooth that has a painful, inflamed nerve but no infection at the root tip.
AjmanAges 20–50 - NCT06647381Enrolling by invitation
Long-term outcomes of implants with sinus lifts
This study looks at how well dental implants hold up many years after a sinus lift procedure. If you had a sinus lift and implant around 1997–2001 at the University of Bern, you may be asked to come in for an exam to check your implant health.
BernAges 18–100 - NCT06677983Recruiting
How well do Bioflx crowns work for children's back baby teeth?
This study tests how well children and parents like a new type of crown for baby molars. The crowns are placed on back baby teeth that need full coverage, and the study looks at how they perform and how comfortable and satisfied you and your child are.
AlexandriaAges 4–8 - NCT06642415Recruiting
High magnification microscope for tooth root surgery
This trial compares two ways of doing a special tooth surgery (endodontic microsurgery) to see if using a high-magnification microscope helps you feel better after the procedure. If you have a tooth that still hurts or stays infected after a previous root canal, this study might be for you.
Rohtak, HaryanaAges 18–55 - NCT06516263Recruiting
Effect of L-PRF on dental implant stability and bone levels
This trial tests if a special blood concentrate (L-PRF) placed around dental implants can help them heal better and keep bone levels stable. It may be an option if you need one or more dental implants and have enough natural bone without needing a graft.
DublinAges 18 years+ - NCT06543186Recruiting
Virtual world for teen oral health education
This study tests whether a fun virtual world (metaverse) can help teenagers learn how to take care of their teeth and gums better. You would use a computer program during school to see if it makes oral health easier to understand and remember.
Bentong, PahangAges 15–16 - NCT06553300Recruiting
Moving wisdom teeth to replace missing teeth
This study tests if a wisdom tooth that hasn't fully formed can be moved to replace a missing tooth. It might help you avoid a dental implant or bridge.
Cleveland, OhioAges 18–50
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,057 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,953 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.