Clinical trials
Acute Respiratory Failure clinical trials
Below are recruiting acute respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07279831Recruiting
Brain-lung interaction study in acute respiratory failure
This trial looks at how the lung and brain communicate during serious breathing problems. If you are in the ICU with a new breathing issue and need high-flow oxygen therapy, researchers want to study your brain and lung activity together.
ParisAges 18 years+ - NCT06051292Recruiting
Testing balloon size for lung pressure measurement in children
This study tests how much air to put in a small balloon in the esophagus (feeding tube-like device) to measure lung pressure more accurately. It is for children on a breathing machine whose settings are stable for the next 2 hours.
AydinAges 1 month–18 years - NCT06357780Recruiting
Comparing two breath-timing methods for breathing masks in adults
This study compares two ways of timing a breathing mask's support to match your own breaths. If you're in the ICU or ER and need help breathing for at least 2 more hours, this trial may test which method works better.
IzmirAges 18 years+ - NCT07265882Recruiting
Bedside test for breathing tube patients
This trial uses a simple bedside test to evaluate patients who are on a breathing machine and not breathing on their own. It may help doctors better understand and manage acute respiratory failure.
Pavia, PaviaAges 18–90 - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT04912960Recruiting
PEEP breathing support for adults with acute lung failure
This trial studies whether a specific breathing setting called PEEP can help adults whose lungs are failing and who need a breathing machine. Doctors will compare outcomes in patients who fit this critical illness pattern and are safe for the required positioning and ventilator settings.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07189078Recruiting
Comparing intubation methods for patients with low blood oxygen
This study tests two different ways to place a breathing tube in patients who are in intensive care with very low oxygen levels and need help breathing. The goal is to find which method is safer and works better for patients like you.
AngersAges 18 years+ - NCT07188038Recruiting
Comparing low vs high breathing tube pressure on diaphragm health
This trial compares two levels of positive end-expiratory pressure (PEEP) in patients on a breathing machine. It looks at how these pressures affect diaphragm function, how well the lungs work, and how efficiently you breathe.
Gothenburg, Västra Götaland CountyAges 18 years+ - NCT06936618Recruiting
Electrical impedance guided ventilator settings for breathing failure
This trial tests whether using electrical impedance tomography (EIT), a safe and non-invasive monitoring technique, helps doctors set the ventilator better for patients with low oxygen levels. It may improve your breathing support during mechanical ventilation.
BangkokAges 18 years+ - NCT07175194Recruiting
Matching lung scans to ventilator settings in acute breathing failure
This study uses two lung imaging tests—CT scan and EIT (a non-invasive electrical test)—to find the best ventilator pressure for people with sudden breathing failure. The goal is to tailor settings to your lungs and potentially improve breathing support.
Milan, MilanAges 18 years+ - NCT07168213Recruiting
Comparing oxygen monitors during high-flow nasal oxygen
This study tests whether two different oxygen monitors change how much extra oxygen doctors give you during high-flow nasal oxygen therapy. If you are in the ICU and already on this type of oxygen, the researchers want to see if using a different monitor helps keep your oxygen levels stable.
Québec, QuebecAges 18 years+ - NCT07157696Recruiting
Advanced oxygen monitoring for chronic lung or heart disease
This study tests a more advanced way to monitor oxygen levels and deliver oxygen therapy at home for people with chronic lung or heart conditions who have acute breathing problems. It aims to see if this approach improves care and quality of life.
Ferrara, ItalyAges 18–80 - NCT07083973Recruiting
Monitoring lung function with 3D imaging in ARDS
This study is testing a new way to monitor lung function using a 3D electrical imaging device (EIT) while patients with ARDS lie on their stomach to improve breathing. The goal is to see if this imaging helps doctors better understand how the lungs are working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT06716463Recruiting
Predicting breathing support failure with wearable monitoring
This study tests if a wearable chest monitor can predict when breathing support (like a mask or nasal prongs) might stop working, so doctors can act faster. It is for hospital patients who need help breathing but are not on a breathing tube.
Toronto, OntarioAges 18 years+ - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT06989385Recruiting
Studying breathing support failure in respiratory failure
This study looks at why some patients with acute respiratory failure do not improve with non-invasive breathing support like high-flow nasal oxygen (HFNO) or non-invasive ventilation (NIV). It aims to find patterns that might predict when these treatments are not enough.
ModenaAges 18 years+ - NCT06967441Recruiting
Respiratory viruses and acute heart failure study
This trial looks at whether a respiratory virus might be triggering your heart failure. It will test your nasal swab for viruses to help doctors understand and treat your condition better.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06952816Recruiting
Testing EMILY AI for respiratory failure
This study tests a new AI device (EMILY) that helps monitor breathing problems like acute respiratory failure. You may join if you are in a hospital for respiratory care and meet certain health criteria.
MadridAges 18 years+ - NCT06931938Recruiting
Awake Prone Position for Pneumonia and Low Oxygen
This trial tests whether lying on your stomach while awake (called awake prone positioning) can help people with pneumonia who have low oxygen levels in the ICU. It aims to see if this simple position change can improve breathing and avoid the need for a breathing machine.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06912360Recruiting
CPAP support for severe breathing failure in Burkina Faso
This trial tests if CPAP, a breathing machine that keeps airways open, helps adults with severe breathing problems and low oxygen levels. It is for people in Burkina Faso who need extra oxygen to breathe well.
Bobo-Dioulasso, HouetAges 18 years+ - NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT06669312Recruiting
Study on a model for ICU patients on high-flow oxygen
This study is testing an existing model (BREF) to see how well it helps doctors make decisions for patients on high-flow oxygen in the intensive care unit. It may help improve care for people needing extra breathing support.
Rozzano, MilanAges 18 years+
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Common questions
- Are there clinical trials for acute respiratory failure?
- Yes. Clin2 currently lists 172 recruiting acute respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.