Clinical trials
Degenerative Disc Disease Lumbar clinical trials
Below are recruiting degenerative disc disease lumbar clinical trials, each written for real people, not researchers. We’re tracking 42 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07085247Recruiting
Role of bacteria in lower back disc disease
This trial looks at whether a specific bacteria, Cutibacterium acnes, is linked to disc problems in the lower back. If you're having surgery for a herniated disc, your tissue sample may help researchers understand the cause.
BrnoAges 18 years+ - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07168603RecruitingPhase 1/Phase 2
Testing own disc cells for low back pain from a herniated disc
This trial tests whether your own disc cells (nucleus pulposus cells) can help heal a herniated disc and reduce pain. It is for people who have had low back pain for more than six weeks and are scheduled for disc surgery.
TaipeiAges 20 years+ - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT07615491Recruiting
Safety and effectiveness study of spinal implants and bone materials
This study tracks how well spinal implants (Titania systems) and bone-filling materials (BONEGRAFT) work after surgery and whether patients experience any problems. Researchers will follow patients after cervical or lower spine surgery to confirm these devices are safe and effective in real-world use.
IzmirAges 18 years+ - NCT07001969Enrolling by invitation
Percutaneous facet spine fixation for instability
This study tests a minimally invasive procedure to fix unstable vertebrae in the neck or lower back using a small incision. It may help people with spinal instability causing nerve symptoms or pressure on the spinal cord.
Cairo, ShoroukAges Any age - NCT06686017Enrolling by invitation
New bone graft for lower back fusion surgery
This trial studies a new bone graft material called Virtuos for use in lower back spinal fusion surgery. It may help patients needing a one or two-level lumbar fusion by providing a safe and effective option for bone healing.
South Bend, IndianaAges 18 years+ - NCT06000319Enrolling by invitation
NMP fibers for spine fusion surgery
This study tests a new material called NMP fibers used during spine fusion surgery to treat conditions like degenerative disc disease, spinal stenosis, or spondylolisthesis. The goal is to see how well it works for patients having fusion in the neck or lower back.
Jasper, AlabamaAges 18 years+ - NCT04418830Enrolling by invitation
Study of a spine cage implant for degenerative back problems
This trial studies how well specific lumbar (lower back) implant “cages” help fuse vertebrae in people with degenerative disc disease, spinal slippage, narrowing, curvature, or forward-bending deformity. It may help by testing an approach to improve stability and reduce symptoms after surgery.
La Jolla, CaliforniaAges 18 years+ - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT07587775Enrolling by invitationPhase 2
Osteoporosis Medication Effects on Spine Bone Quality
This study tests how a bone-strengthening medication called Abaloparatide affects the quality of bones in your lower spine. Researchers will use imaging scans to see if the medication helps improve bone strength in people with osteoporosis who also have spine wear-and-tear.
Buffalo, New YorkAges 50 years+ - NCT06971835Enrolling by invitation
NanoParticle Matrix spine surgery registry
This study follows people who receive a special bone graft material called NanoParticle Matrix (NPM) during spine surgery. Researchers want to track outcomes over two years to see how well it works.
Baton Rouge, LouisianaAges 18 years+ - NCT03649490Enrolling by invitation
Testing new spinal implant materials for XLIF fusion
This study compares different advanced materials used in a specific spinal fusion surgery (XLIF). It aims to see which implant material helps the bone fuse well and safely over time.
Hartford, ConnecticutAges 18–80 - NCT04407338Recruiting
B-DYN device versus standard fusion for lumbar stenosis
This trial compares a specific spinal fusion approach (B-DYN) with the standard fusion surgery for people with lumbar spinal stenosis. It aims to improve function after surgery and check whether the newer approach is well tolerated.
BordeauxAges 40 years+ - NCT07217964Enrolling by invitation
Study of natural protein for spinal fusion surgery
This trial is testing a natural protein material used during spinal fusion surgery to treat lower back pain caused by worn-out discs. It may help patients who haven't gotten better with other treatments and need surgery on up to four levels of the lower spine.
New York, New YorkAges 18 years+ - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05066334RecruitingPhase 2
Back pain trial using your own stem cells in discs
This Phase 2 trial tests whether injecting your own stem cells into a few back discs can reduce chronic low back pain that has not improved with standard treatments. It may help by targeting disc-related (degenerative) wear seen on MRI, but it requires detailed MRI and blood test screening.
Roma, ItalyAges 18–65
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Common questions
- Are there clinical trials for degenerative disc disease lumbar?
- Yes. Clin2 currently lists 42 recruiting degenerative disc disease lumbar studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a degenerative disc disease lumbar trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a degenerative disc disease lumbar trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.