Clinical trials
Extubation clinical trials
Below are recruiting extubation clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06975553Enrolling by invitation
Using a carbon dioxide monitor to guide safe breathing-tube removal
This study tests a special carbon dioxide monitor to help decide when it's safe to remove your breathing tube after abdominal surgery. If you are having a planned abdominal procedure lasting 1–4 hours, you may be able to join.
Beijing, Beijing MunicipalityAges 18–80 - NCT05069441Recruiting
Predicting breathing trouble after removing a breathing tube
This study looks at patients who are ready to have their breathing tube removed and checks how to predict who might struggle after extubation. It’s observational, meaning your care won’t be changed—researchers are gathering information to improve future predictions.
ChongqingAges 18 years+ - NCT07110129Recruiting
Testing a new tool to see if you're ready to come off the breathing machine
This study tests a new way to check if your breathing muscles are strong enough to safely remove the breathing tube. It uses a special patch to measure how well your diaphragm works, which may help doctors make better decisions about when to take the tube out.
CardiffAges 18 years+ - NCT07093125Recruiting
Rehabilitation for ICU patients on a breathing machine
This trial is studying rehabilitation practices for people in the ICU who need a breathing machine (ventilator) for at least 48 hours. It aims to improve recovery and care for critically ill patients.
Genova, ItalyAges 16–100 - NCT07519512Recruiting
Early Switch to Assisted Breathing in ICU Patients
This study tests whether moving ICU patients from fully machine-controlled breathing to partially assisted breathing earlier helps them get off ventilators successfully. The goal is to see if this approach reduces the time patients need mechanical ventilation.
Nanjing, JiangsuAges 18 years+ - NCT07007715Recruiting
Finding the best oxygen flow setting after extubation
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
TaipeiAges 18 years+ - NCT06878703RecruitingPhase 3
Dexmedetomidine vs midazolam for preterm babies on a ventilator
This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.
ParisAges Up to 7 months - NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients
This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.
Tanta, MahalaAges 18–65 - NCT07383051Recruiting
Helping children breathe on their own after ventilator support
This trial tests whether a special type of high-flow nasal therapy can help children come off a breathing machine (ventilator) more successfully. It compares standard care with this extra support to find what works best for kids ages 2 months to 13 years.
Cairo, Cairo GovernorateAges 2 months–13 years - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT07734298Recruiting
Ultrasound vs. scope for swallowing problems after ICU breathing tube
This study compares two ways to check swallowing after a breathing tube is removed in the ICU: one uses an ultrasound machine, the other uses a small camera through the nose. If you qualify, you may help doctors find the best method to spot swallowing issues early.
Querétaro City, QuerétaroAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT05446272Recruiting
Helps premature babies breathe during breathing tube removal
This trial tests a breathing-support method (called DIVA) to help premature babies breathe safely when the breathing tube is taken out. It may help more babies transition off the ventilator and avoid breathing problems during extubation.
Little Rock, ArkansasAges birth–2 months - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT05837936Recruiting
IV anesthesia approach for young children during surgery
This study compares two ways of giving anesthesia to children under 10 during surgery, with a focus on how the child wakes up and breathes when the breathing tube is removed. It may help doctors choose safer, smoother anesthesia for pediatric surgeries.
Winston-Salem, North CarolinaAges Up to 9 years - NCT05839756Recruiting
Predicting throat swelling after jaw surgery removal of a breathing tube
This trial studies how to predict who is most likely to develop a noisy, tight throat (stridor) after doctors remove the breathing tube following a jaw-stabilizing surgery. It may help clinicians spot higher-risk patients earlier so they can take preventive steps.
Al Mansurah, MansouraAges 18 years+ - NCT05865977Recruiting
Test a breathing check to prevent breathing tube failure in preemies
This study checks a specific bedside breathing test (called an SBT) to see if it can better predict when a premature baby is likely to fail extubation (having the breathing tube removed). If the test is accurate, it may help doctors time tube removal more safely and reduce complications.
Chongqing, Chongqing MunicipalityAges 2 days–6 months - NCT06037083Recruiting
Checking stability after breathing tube removal in tiny preemies
This study looks at how stable extremely premature, very low-weight babies are after their breathing tube is removed for the first time. It aims to understand what helps these tiny infants breathe well on their own.
Montreal, QuebecAges Up to 6 months - NCT06401083RecruitingPhase 4
Extra caffeine dose before removing breathing tube in preemies
This study tests if giving an extra dose of caffeine (a medicine that helps premature babies breathe) right before removing the breathing tube can make the transition easier. It is for very premature babies who have been on a ventilator for at least two days and are ready for their first try at breathing on their own.
BudapestAges Any age - NCT06469580Recruiting
Lung ultrasound to guide breathing tube removal in newborns
This study tests whether using lung ultrasound helps doctors decide the best time to remove a breathing tube from preterm and full-term newborns. It may reduce the chance of needing to put the tube back in.
Graz, StyriaAges 1 minute–6 months - NCT06511284Recruiting
Nutrition therapy for swallowing problems after breathing tube removal
This study tests whether specialized nutrition therapy can help patients who have trouble swallowing after a breathing tube is removed. The goal is to improve recovery and quality of life for people who need a feeding tube after leaving the hospital.
Mexico CityAges 18 years+ - NCT06531005Recruiting
Checking breathing to predict when a breathing tube can be removed in the ICU
This study looks at how well current breathing measures predict a patient's readiness to have their breathing tube removed in the intensive care unit (ICU). It aims to make the decision to remove the tube safer and more accurate.
Altindağ, AnkaraAges 18 years+ - NCT06591533Recruiting
Music therapy for children during breathing tube removal
This study uses music therapy to help children stay calm and have stable vital signs while their breathing tube is removed. It may help reduce stress during this important step.
Bogotá, Bogota D.C.Ages 1 month–17 years
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Common questions
- Are there clinical trials for extubation?
- Yes. Clin2 currently lists 65 recruiting extubation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extubation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extubation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.