Clinical trials
Extubation Failure clinical trials
Below are recruiting extubation failure clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07098611Recruiting
New tool to predict readiness for breathing tube removal
This study tests a new scoring tool to help doctors decide when a patient on a breathing machine is ready to have the tube removed safely. It is for patients who are currently in the process of being weaned off the ventilator.
Punta ArenasAges 18–89 - NCT06557941Recruiting
Risk factors for breathing tube removal failure in children
This study looks at why some children in the pediatric ICU have trouble coming off the breathing machine (ventilator). If your child is ready to try stopping the ventilator, this trial will help doctors understand what may make that transition safer.
SohagAges 4 weeks–18 years - NCT07752173Recruiting
Recovery from breathing tube after surgery: day vs night
This study compares how well patients recover from the breathing tube (extubation) after surgery, depending on whether it happens during the day or at night. The goal is to see if there are more breathing complications at night so hospitals can improve care.
Kocaeli, IzmıtAges 18 years+ - NCT06716463Recruiting
Predicting breathing support failure with wearable monitoring
This study tests if a wearable chest monitor can predict when breathing support (like a mask or nasal prongs) might stop working, so doctors can act faster. It is for hospital patients who need help breathing but are not on a breathing tube.
Toronto, OntarioAges 18 years+ - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT06808997Recruiting
Study on breathing support decisions for very early preterm babies
This study looks at how doctors decide when to remove the breathing tube (extubation) from extremely preterm babies born before 28 weeks of pregnancy. It aims to understand what affects breathing outcomes and could help improve care for these tiny infants.
AmiensAges 1 minute–5 months - NCT07019636Recruiting
Direct extubation vs. extubation after a breathing trial
This study compares two ways of removing the breathing tube (extubation) in patients who are ready to breathe on their own: taking the tube out right away, or doing a trial of breathing without the machine first. It is for people who are at low risk of needing the tube put back in.
ParisAges 18–65 - NCT06671015Recruiting
Comparing breathing support methods after a breathing tube is removed in people with heart failure
This study compares two types of breathing support—a high-flow nasal cannula and noninvasive ventilation—to see which one better prevents the need for re-inserting a breathing tube in people with systolic heart failure who are at high risk for breathing problems after the tube is removed.
New Haven, ConnecticutAges 18 years+ - NCT05918575Recruiting
Breathing support after a breathing tube in very obese adults
This trial tests whether giving noninvasive breathing support (using a mask or similar device, without a new breathing tube) right after removing a breathing tube works better for severely obese adults. It mainly looks at people at higher risk of needing help breathing again after extubation.
Chicago, IllinoisAges 18 years+ - NCT06450678Recruiting
Can a physiotherapy test predict breathing tube removal success?
This study checks if a quick physical therapy exam can predict whether a person will need the breathing machine again after it is removed. It is for adults who have been on a ventilator for more than two days and have already shown they can breathe on their own for a short time.
ParisAges 18 years+ - NCT05069441Recruiting
Predicting breathing trouble after removing a breathing tube
This study looks at patients who are ready to have their breathing tube removed and checks how to predict who might struggle after extubation. It’s observational, meaning your care won’t be changed—researchers are gathering information to improve future predictions.
ChongqingAges 18 years+ - NCT07093125Recruiting
Rehabilitation for ICU patients on a breathing machine
This trial is studying rehabilitation practices for people in the ICU who need a breathing machine (ventilator) for at least 48 hours. It aims to improve recovery and care for critically ill patients.
Genova, ItalyAges 16–100 - NCT05446272Recruiting
Helps premature babies breathe during breathing tube removal
This trial tests a breathing-support method (called DIVA) to help premature babies breathe safely when the breathing tube is taken out. It may help more babies transition off the ventilator and avoid breathing problems during extubation.
Little Rock, ArkansasAges birth–2 months - NCT05865977Recruiting
Test a breathing check to prevent breathing tube failure in preemies
This study checks a specific bedside breathing test (called an SBT) to see if it can better predict when a premature baby is likely to fail extubation (having the breathing tube removed). If the test is accurate, it may help doctors time tube removal more safely and reduce complications.
Chongqing, Chongqing MunicipalityAges 2 days–6 months - NCT06469580Recruiting
Lung ultrasound to guide breathing tube removal in newborns
This study tests whether using lung ultrasound helps doctors decide the best time to remove a breathing tube from preterm and full-term newborns. It may reduce the chance of needing to put the tube back in.
Graz, StyriaAges 1 minute–6 months - NCT07467265Recruiting
Testing a breathing test to safely remove ventilators
This study is testing a simple way to measure how well you breathe on your own when coming off a ventilator in the ICU. It helps doctors decide the best time to safely remove the breathing tube.
Cairo, AbbasiaAges 22 years+ - NCT05686850Recruiting
Noninvasive breathing support vs high-flow oxygen after ICU extubation
This study compares two breathing supports used after a breathing tube is removed in the ICU: a noninvasive ventilator (mask-based) versus high-flow nasal oxygen. It aims to see which one works better when patients develop breathing trouble soon after extubation.
BrusselsAges 18 years+ - NCT07007715Recruiting
Finding the best oxygen flow setting after extubation
This trial tests different flow rates for a high-flow nasal cannula (a device that delivers warm, moist oxygen) after a breathing tube is removed. It aims to find the best setting for patients moving from a ventilator to breathing on their own.
TaipeiAges 18 years+ - NCT06591533Recruiting
Music therapy for children during breathing tube removal
This study uses music therapy to help children stay calm and have stable vital signs while their breathing tube is removed. It may help reduce stress during this important step.
Bogotá, Bogota D.C.Ages 1 month–17 years - NCT07114289Recruiting
Breathing test methods for overweight patients on ventilators
This study compares two ways of testing if overweight or obese patients can breathe on their own after being on a ventilator. You will be randomly assigned to one of two breathing trials (pressure support or a T-piece) to see which works better for helping you get off the ventilator.
TaipeiAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06531005Recruiting
Checking breathing to predict when a breathing tube can be removed in the ICU
This study looks at how well current breathing measures predict a patient's readiness to have their breathing tube removed in the intensive care unit (ICU). It aims to make the decision to remove the tube safer and more accurate.
Altindağ, AnkaraAges 18 years+ - NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients
This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.
Tanta, MahalaAges 18–65 - NCT06401083RecruitingPhase 4
Extra caffeine dose before removing breathing tube in preemies
This study tests if giving an extra dose of caffeine (a medicine that helps premature babies breathe) right before removing the breathing tube can make the transition easier. It is for very premature babies who have been on a ventilator for at least two days and are ready for their first try at breathing on their own.
BudapestAges Any age
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Common questions
- Are there clinical trials for extubation failure?
- Yes. Clin2 currently lists 24 recruiting extubation failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a extubation failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a extubation failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.