Clinical trials
Heart Failure NYHA Class II clinical trials
Below are recruiting heart failure nyha class ii clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06561932Recruiting
Leadless pacemaker for heart failure resynchronization
This trial tests a completely leadless pacemaker (WiSE® CRT) for heart failure patients who need cardiac resynchronization therapy (CRT). It aims to avoid the long-term risks of traditional wires (leads) in the heart.
Birtinya, QueenslandAges 22 years+ - NCT06793371RecruitingPhase 2
Study of CK-4021586 for heart failure with preserved ejection fraction
This trial tests an investigational drug called CK-4021586 for people with heart failure with preserved ejection fraction (HFpEF). It aims to see if the drug is safe and well-tolerated. You may qualify if you are 40 to 85, have heart failure symptoms, and have a heart that pumps well but shows signs of strain.
Fairhope, AlabamaAges 40–85 - NCT06876441Recruiting
Home Tai Chi Program for Heart Failure Patients and Caregivers
This study tests if a home-based Tai Chi program using a smartphone app can improve the health and well-being of people with chronic heart failure who are mostly sedentary. It also looks at how this program affects their caregivers, who will practice Tai Chi alongside them.
Qingdao, ShandongAges 18–75 - NCT07084142Recruiting
Digital aid for ICD decisions
This study is developing a digital tool to help people 70 and older with heart failure decide whether an ICD (a device that prevents dangerous heart rhythms) is right for them. Participants will help test and improve this tool.
San Francisco, CaliforniaAges 60 years+ - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07281014RecruitingPhase 4
Testing a different approach to heart failure medication
This trial is for people with stable, mild heart failure. It tests a new way of using a standard medicine (spironolactone) to see if it works better at a different dose. The study lasts 8 weeks.
New Haven, ConnecticutAges 18 years+ - NCT06299514Recruiting
Pacemaker and ablation for heart failure with atrial fibrillation
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Victoria, British ColumbiaAges 18 years+ - NCT07643818Enrolling by invitationPhase 2
Iron Infusions for Heart Failure and Iron Deficiency
This trial tests whether intravenous iron infusions can help people with heart failure (preserved ejection fraction) who also have low iron levels. The goal is to improve symptoms, quality of life, and how far you can walk.
Saint HelierAges 18 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT06241430Recruiting
CardioClip study: testing a new valve repair for leaky heart valve
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
New York, New YorkAges 18–90 - NCT07489547RecruitingPhase 2/Phase 3
Can stable heart failure patients stop some medications?
This trial is testing whether people whose heart failure has improved (with better pumping strength) can safely stop taking some of their heart medications. It is for stable patients who have had significant improvement in their heart function from a low point.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06930495Enrolling by invitation
Weight loss and heart failure with normal pumping strength
This study tests whether weight loss treatments can improve muscle and blood vessel function in people with a specific type of heart failure (HFpEF) who also have obesity. It may help if you have heart failure with a normal ejection fraction and a high BMI.
Dallas, TexasAges 18 years+ - NCT05279742Enrolling by invitationPhase 1/Phase 2
Study drug to boost a hormone system in HFpEF
This early-phase trial tests a treatment that aims to improve the “natriuretic peptide” hormone system in people with HFpEF (heart failure with preserved pumping strength). It may help reduce symptoms and improve heart and fluid pressure behavior, especially in certain related conditions like kidney disease.
Rochester, MinnesotaAges 18 years+ - NCT07284836RecruitingPhase 2
Chemo directly to liver for breast cancer
This trial tests a new way to give chemotherapy directly to the liver for breast cancer that has spread only there. It's for people who have already tried two or more standard treatments.
Hangzhou, ZhejiangAges 18–70
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Common questions
- Are there clinical trials for heart failure nyha class ii?
- Yes. Clin2 currently lists 158 recruiting heart failure nyha class ii studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a heart failure nyha class ii trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a heart failure nyha class ii trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.